The WHO continues to issue regular updates on both A/(H1N1) and A/(H5N1) posted on the WHO main page, as well as other advisories linked from that page. Here are the current updates:

– Pandemic (H1N1) 2009 – update 58

6 July 2009 – The title of this update has now evolved to “Pandemic (H1N1) 2009.” WHO notes 94,512 officially reported cases of influenza A(H1N1) infection (up from 59,814 a week ago and 44,287 a week earlier), including 429 deaths (up from 263 a week ago and 180 a week earlier). [no update to 6 July report published as of 11 July 2009: 06.25]

http://www.who.int/csr/don/2009_07_06/en/index.html

WHO has included an interactive “timeline of all cases” (requires Flash player) at:

http://gamapserver.who.int/h1n1/atlas.html?select=ZZZ&filter=filter4,confirmed

– Pandemic (H1N1) 2009 briefing note 1

Viruses resistant to oseltamivir (Tamiflu) identified

8 July 2009 – [full text]

WHO said it has been informed by health authorities in Denmark, Japan and the Special Administrative Region of Hong Kong, China of the appearance of H1N1 viruses which are resistant to the antiviral drug oseltamivir (known as Tamiflu) based on laboratory testing. These viruses were found in three patients who did not have severe disease and all have recovered. Investigations have not found the resistant virus in the close contacts of these three people. The viruses, while resistant to oseltamivir, remain sensitive to zanamivir.

WHO said that close to 1000 pandemic H1N1 viruses have been evaluated by the laboratories in the Global Influenza Surveillance Network for antiviral drug resistance. All other viruses have been shown sensitive to both oseltamivir and zanamivir. WHO and its partners will continue to conduct ongoing monitoring of influenza viruses for antiviral drug resistance.

Therefore, based on current information, these instances of drug resistance appear to represent sporadic cases of resistance. At this time, there is no evidence to indicate the development of widespread antiviral resistance among pandemic H1N1 viruses. Based on this risk assessment, there are no changes in WHO’s clinical treatment guidance. Antiviral drugs remain a key component of the public health response when used as recommended.

http://www.who.int/csr/disease/swineflu/notes/h1n1_antiviral_resistance_20090708/en/index.html

– Cumulative Number of Confirmed Human Cases of Avian Influenza A/(H5N1) Reported to WHO

1 July 2009  [No update since 1 July 2009]

The published tabular chart reports 436 confirmed cases (up from 433 cases reported as of 2 June 2009) and 262 deaths (unchanged from the 2 June 2009 report).

http://www.who.int/csr/disease/avian_influenza/country/cases_table_2009_06_02/en/index.html