Vaccines and Global Health: The Week in Review 16 September 2017

Vaccines and Global Health: The Week in Review is a weekly digest  summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated with the current issue date

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– blog edition: comprised of the approx. 35+ entries posted below.

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David R. Curry, MS
Executive Director
Center for Vaccine Ethics and Policy

Milestones :: Perspectives

Milestones :: Perspectives
 
The Mérieux Fondation is celebrating 50 years of fighting infectious diseases in developing countries
Les Pensiéres Center for Global Health, Veyrier-du-Lac (France)
September 14, 2017
Calling for all public and private stakeholders worldwide to rally together and international health diplomacy, it reasserts France’s central role.
To mark its 50th anniversary, the Foundation is organizing an International Meeting at the Les Pensières Center for Global Health on the shores of Lake Annecy. The aim of this day is to highlight new collaborative international approaches for fighting the increased risk of epidemics.

The threat of infectious disease is ever present, accounting for nearly 17 million victims each year, most of whom are children in developing countries. This threat is now taking on a new dimension in light of an increasing number of conflicts, demographic explosion, massive migrations of populations, accelerating global exchanges of all kinds and climate change – a context for which humans are largely responsible.

Traditional top-down approaches have demonstrated their limited efficacy in combating infectious diseases. They must now give way to new, local initiatives, conducted with and for the residents of those communities. Multidisciplinary approaches to global health go beyond merely treating patients, encompassing everything in the environment that impacts patients.

France has a role to play in this global fight, due to its expertise in infectious disease, Pasteurian tradition and the historical global influence of French medicine. As such, it needs to reassert its position and ensure it is an integral part of the wider framework of international health diplomacy, which is yet to be formed. The Foundation is ready to commit to this cause and provide its expertise in biology in the field.

To this end, over 150 scientists, researchers, doctors, biologists, humanitarian players and representatives from international organizations, hailing from West Africa, Asia, Latin America, Madagascar, Haiti and the Middle East are meeting together today to share their experiences at three round tables dedicated to key challenges:
:: Epidemic risks in developing countries, chaired by Professor Christian Bréchot, President of Institut Pasteur
:: New dynamics in health capacity building: leveraging local resources, chaired by Professor Ogobara Doumbo, Director of the Malaria Research and Training Centre, Faculty of Medicine, University of Bamako, Mali
:: The global health approach: bringing vulnerable populations more than medical care, chaired by Dr. Jean William Pape, Founder and Director of the GHESKIO Centers, Haiti

A single model for action to combat infectious diseases
For the past 50 years, the Mérieux Foundation has been committed to fighting infectious diseases affecting developing countries by strengthening their clinical biology capabilities.

Without diagnostics, medicine is blind. The Mérieux Foundation has therefore made its commitment to diagnostics the driving force behind its work. Diagnostics are an essential part of the healthcare chain and an invaluable tool for identifying pathogens responsible for disease and prescribing suitable treatment. They are therefore key to fighting bacterial resistance and, more globally, indispensable for disease surveillance and control.

The Foundation is focusing its actions on:
:: Creating and equipping laboratories of excellence, the Rodolphe Mérieux Laboratories;
:: Around these reference laboratories, renovating clinical laboratories in the field to give local populations access to quality diagnostics;
:: On-site training of new generations of healthcare players in these countries;
:: Rolling out international applied research programs, coordinated by its GABRIEL research network;
:: Building international research and diagnostic networks worldwide;
:: Developing global health programs to treat the most vulnerable, namely mothers and children.

Presided by Alain Mérieux, the Mérieux Foundation has public interest status and carries out its actions in concert with Fondation Christophe et Rodolphe Mérieux, an independent family foundation created in 2001 under the aegis of the Institut de France. Fondation Christophe et Rodolphe Mérieux is a 30% shareholder of the Institut Mérieux and is the sole beneficiary of the dividends paid out by the Institut.

The Mérieux Foundation employs over 100 people working in France and in developing countries and dedicates an annual budget of nearly €25 million to its actions in the field. Close to half this budget is provided by the family…
 
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PATH announces new collaboration to advance maternal immunization in low- and middle-income countries
Announcement | September 11, 2017
The Advancing Maternal Immunization collaboration will create a roadmap to help infants survive and thrive by making immunization available to pregnant mothers
A newly launched collaboration is bringing together stakeholders from around the world to improve infant health and survival through maternal immunization, particularly in low- and middle-income countries (LMICs). The newly assembled Advancing Maternal Immunization (AMI) collaboration is meeting an urgent need for pregnant mothers in LMICs to be able to protect their babies from infectious diseases by getting vaccinated themselves—an option not used to its full potential in many parts of the world, especially in resource-limited settings where it is not widely available.
With a current focus on respiratory syncytial virus (RSV)—which is estimated to cause more than a quarter of global respiratory deaths (nearly 120,000) among children younger than five years of age annually—AMI aims to ensure that a successful RSV vaccine is made available to women in LMICs without delay. No licensed vaccine exists to prevent RSV, but a number of vaccine candidates are advancing, including a maternal vaccine in late-stage development that may be available in the next few years.
Coordinated by PATH in collaboration with the World Health Organization (WHO) and funded by the Bill & Melinda Gates Foundation, AMI will start by developing a roadmap to facilitate informed global, regional, and country decisions around RSV maternal vaccines. It will also identify requirements to enable rapid launch and uptake in LMICs…
 
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New Gates Foundation Report Highlights Remarkable Progress Against Global Poverty and Disease, Warns Future Progress in Jeopardy
Bill and Melinda Gates Call for Strong Leadership to Address “Solvable Human Misery”
SEATTLE, Sept. 13, 2017 – The Bill & Melinda Gates Foundation today launched an inaugural annual report showcasing the remarkable progress that has been made in reducing extreme poverty and disease in recent decades, but issuing a stern warning to the world that future progress is in jeopardy.

Goalkeepers: The Stories Behind the Data, co-authored and edited by Bill and Melinda Gates and produced in partnership with the Institute for Health Metrics and Evaluation at the University of Washington, highlights past progress against some of the most devastating issues facing poor countries and uses breakthrough data projections to forecast good and bad future scenarios – with millions of lives hanging in the balance.

In all, the report tracks 18 data points from the UN Sustainable Development Goals, or Global Goals, including child and maternal deaths, stunting, access to contraceptives, HIV, malaria, extreme poverty, financial inclusion and sanitation. The report looks beneath the numbers to pinpoint the leaders, approaches and innovations that made a difference.

Through the data and first-person accounts from six contributors, the report showcases the stunning progress the world has made in the past generation: cutting extreme poverty and child deaths in half and reducing HIV deaths and maternal deaths by nearly half, among many other accomplishments. But as the report shows, serious challenges remain – including deep disparities between countries – and future progress is not inevitable.

The projections are showcased in charts and explore three potential 2030 scenarios for each indicator. The first is what could happen if we continue along the current path, based on past trends – without significant changes to approaches or current spending levels. Two additional scenarios provide a glimpse at a better and worse future: what could happen with strong leadership, innovation and investment and, starkly, what could happen if attention and funding waned. For example, a mere 10 percent cut in global donor funding for HIV treatment could result in more than 5 million more deaths by 2030…

Goalkeepers: The Stories Behind the Data 2017
Bill & Melinda Gates Foundation, 2017 :: 44 pages
PDF: http://www.globalgoals.org/goalkeepers/datareport/assets/downloads/Stories_behind_the_data_2017.pdf
[Excerpt p. 35]
VACCINES
Proportion of the target population covered by eight vaccines, conditional on inclusion in national vaccine schedules
Vaccines are one of the most impressive success stories in global health. More people are being immunized and protected against more diseases than ever before. The next steps for immunization programs are to battle stagnation by finding the pockets of inequity that exist within countries—even those with high average rates—and reach all children with a full set of lifesaving vaccinations. We’ve grouped countries and plotted the groups separately to show the gap between more and less developed countries.
Target: Support the research and development of vaccines and medicines for the communicable and noncommunicable diseases that primarily affect developing countries and provide access to affordable essential medicines and vaccines. Socio-demographic index (SDI) is a measure based on average income per capita, education attainment, and total fertility rate.
 
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WHO – The 72nd Session of the United Nations General Assembly (UNGA 72)
12 – 25 September 2017
The 72nd Regular Session of the UN General Assembly (UNGA 72) will convene at UN Headquarters on Tuesday, 12 September 2017. The General Debate will open on Tuesday, 19 September 2017, with the theme, ‘Focusing on People: Striving for Peace and a Decent Life for All on a Sustainable Plan
The WHO Delegation to UNGA will be led by Dr Tedros, who will focus on raising awareness and building political commitment to his priority issues of universal health coverage; health security; women’s, children’s and adolescents’ health; and environmental health, including the health impacts of climate change. Dr Tedros, together with Deputy Head of Delegation Dr Flavia Bustreo and other senior officials, will organize and participate to many high-level events, including the flagship WHO event on Universal Health Coverage.
 [Details of major and side events at link above]

Emergencies

Emergencies
 POLIO
Public Health Emergency of International Concern (PHEIC)
Polio this week as of 13 September 2017 [GPEI]
:: Following flooding in Benue, Nigeria, the World Health Organization has deployed its polio infrastructure across the state to strengthen disease prevention efforts.
:: Pakistan and Afghanistan plan to implement National Immunization Days during the second half of September.
:: Summary of newly-reported viruses this week: two new wild poliovirus type 1 (WPV1) positive environmental samples were confirmed this week, one located in Karachi, Pakistan, and the other in Rawalpindi, Pakistan
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Situation reports on the polio outbreak in Syria [WHO]
Situation update 12 September 2017
:: No new cases of cVDPV2 were reported this week. The total number of cVDPV2 cases remains 39. All confirmed cases to date have had onset of paralysis before 14 July 2017.
:: Final lab results are pending for an additional 4 poliovirus type-2 (PV2) isolates (2 from Mayadeen and 1 from Boukamal districts, Deir Ez-Zor governorate, and 1 from Thawra district, Raqqa governorate).
:: The second round for Deir Ez-Zor concluded 28 August. Third party independent monitoring reported coverage of 77% (gauged by caregiver recall).
:: Preparations for the second Raqqa round continue.
:: The Ministry of Health has established healthy children stool sampling in all governorates receiving IDPs from Deir Ez-Zor and Raqqa.
:: IPV is being administered to unvaccinated children under five from Deir Ez-Zor and Raqqa at border checkpoints and entrances in all governorates.
:: The total number of AFP cases detected in Deir Ez-Zor governorate since the beginning of 2017 is 134 (99 from Mayadeen, 10 from Deir Ez-Zor, and 25 from Boukamal districts). Raqqa governorate has reported 16 AFP cases (5 from Raqqa, 10 from Tell Abyad, and 1 from Thawra districts). Homs governorate has reported 30 AFP cases (14 from Homs city, 13 from Rastan, 1 from Tadmour and 2 from Talkalakh districts).
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WHO Grade 3 Emergencies  [to 16 September 2017]
Nigeria
:: WHO Intensifies Efforts to Contain Cholera Outbreak in Borno State
Maiduguri, 08 September 2017-With more than 1000 suspected and confirmed cases of cholera including 30 deaths in Borno state as of 07 Sept 2017, World Health Organization (WHO) has intensified its response efforts to contain the outbreak in Muna internally displaced persons (IDPs)camp in Maiduguri, Jere, Monguno and Dikwa local government areas (LGAs)…
 
The Syrian Arab Republic
:: Situation reports on the polio outbreak in Syria [WHO]  Situation update 12 September 2017
[See Polio above]
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UN OCHA – L3 Emergencies
The UN and its humanitarian partners are currently responding to three ‘L3’ emergencies. This is the global humanitarian system’s classification for the response to the most severe, large-scale humanitarian crises. 
Syrian Arab Republic
:: 15 Sep 2017  After three year siege, UNHCR aid convoy reaches Deir Ez-Zor in eastern Syria
Iraq
:: Iraq: Humanitarian Bulletin, September 2017 | Issued on 15 September
HIGHLIGHTS
…Humanitarian partners prepare for up to 85,000 displaced from Hawiga and surrounding areas.
…Iraq inter-agency toll-free call centre one of a kind in existence.
…Cash Working Group develops joint approach for assistance programmes.
…Iraq Humanitarian Fund prepares new allocation.
…Military operations in Hawiga may affect 85,000
Yemen  No new announcements identified.
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UN OCHA – Corporate Emergencies
When the USG/ERC declares a Corporate Emergency Response, all OCHA offices, branches and sections provide their full support to response activities both at HQ and in the field.
Nigeria 
:: UN Aid Chief: Humanitarian response saves lives in Nigeria’s north-east, civilian safety must be prioritized
(Abuja, 12 September 2017): At the end of a two-day mission to Nigeria, the United Nations Under-Secretary-General for Humanitarian Affairs and Emergency Relief Coordinator, Mark Lowcock, said that the Government and humanitarians had made important progress in delivering life-saving relief to millions of people in north-east Nigeria. However, the complex Lake Chad Basin crisis will require sustained international support over the coming years…
:: Nigeria: Five ways to contain the cholera outbreak
:: Nigeria – North-East Flash Update No. 3 – Cholera Outbreak, 9 September 2017
Somalia 
:: Somalia: Drought Response – Situation Report No. 16  Published on 14 Sep 2017
[Highlights excerpts]
…There is progress on containment of the AWD/cholera outbreak with a significant decline in cases in August.
…Case numbers of measles remain high. A nationwide measles vaccination campaign is scheduled for November/December 2017.Health partners highlight the need for further funding for this campaign.
:: 7 Sep 2017  Somalia Civil-Military Working Group Report – August 2017
 
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Editor’s Note:
We will cluster these recent emergencies as below and continue to monitor the WHO webpages for updates and key developments.
 
MERS-CoV [to 16 September 2017]
http://www.who.int/emergencies/mers-cov/en/
DONS
Middle East respiratory syndrome coronavirus (MERS-CoV) – Oman
12 September 2017
 
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Cholera
Emergency cholera vaccination campaign kicks off in Sierra Leone
FREETOWN, 15 September 2017 – Sierra Leone’s first ever Oral Cholera Vaccination (OCV) campaign kicked off today, September 15th 2017. The emergency campaign targets communities affected by Western Area’s severe floods and landslides, which left over 6,000 people displaced and caused over 500 confirmed deaths.
“The cholera vaccine is safe and available free of cost for everyone living in the affected communities who is over 1 year of age,” said Dr. Brima Kargbo, Chief Medical Officer of the Ministry of Health and Sanitation. “We encourage people in these areas to take the two required doses of the vaccine, which will significantly increase protection against this life-threatening disease.”
Two doses of the vaccine are needed to maximize protection against cholera. The first dose will be administered from 15th to 20th September and the second from 5th to 10th October.  It will be available at health facilities and from health workers who will be going house-to-house in the affected communities and camps.
“Risks of cholera can increase after severe flooding and Sierra Leone has experienced severe outbreaks in the past,” said Alexander Chimbaru, Officer in-Charge of the World Health Organization in Sierra Leone. “In such situations, the cholera vaccine can be a valuable tool to reduce risks, alongside ongoing efforts to improve access to safe water, good hygiene practices and sanitation.”…

 WHO & Regional Offices [to 16 September 2017]

 WHO & Regional Offices [to 16 September 2017]

World hunger again on the rise, driven by conflict and climate change, new UN report says
   15 September 2017 – After steadily declining for over a decade, global hunger is on the rise again, affecting 815 million people in 2016, or 11 per cent of the global population, says a new edition of the annual United Nations report on world food security and nutrition released today.

Highlights
World Sepsis Day 2017
September 2017 – Sepsis is a life-threatening condition that arises when the body’s response to infection causes injury to its own tissues and organs. For World Sepsis Day 2017, WHO and partners are hosting a free online congress to shine a spotlight on neglected aspects of sepsis.

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Weekly Epidemiological Record, 15 September 2017, vol. 92, 37 (pp. 537–556)
:: Meeting of the International Task Force for Disease Eradication, June 2017
 
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WHO Regional Offices
Selected Press Releases, Announcements
WHO African Region AFRO
:: Swaziland conducts Post MR and IPV vaccine Introduction Evaluation 15 September 2017
:: Emergency cholera vaccination campaign kicks off in Sierra Leone  15 September 2017
:: Cameroon investigates yaws outbreak among indigenous populations  15 September 2017
:: Uganda conducts preventative Polio immunization campaign  14 September 2017
:: WHO scales-up accountability processes as workshop on Key Performance Indicators integration opens in Abuja 14 September 2017
:: Mental health is a critical component in disaster response and recovery  13 September 2017
:: Nigeria collaborates with journalists on high quality measles vaccination campaign.
13 September 2017
:: Botswana embarks on a joint review of five health programmes! 13 September 2017
:: WHO supports Government of Uganda to develop a National Action Plan for Health Security (NAPHS)  12 September 2017
:: One year into emergency response, WHO evaluates operations in Northeastern Nigeria.
12 September 2017
:: Integrated Measles and EOS campaign protects 2.6 million children in Ethiopia’s Somali Region  11 September 2017

WHO Region of the Americas PAHO
:: Countries scale up mosquito control efforts for Mosquito Awareness Week (09/13/2017)
:: Wellness Week in the Americas promotes mental well-being (09/11/2017)

WHO South-East Asia Region SEARO
:: Bangladesh/Myanmar: Rakhine Conflict 2017   Situation Report: 01   Date: 15 September 2017
KEY HIGHLIGHTS  [excerpt]
:: Since 25 August more than 379,000 people are estimated to have crossed from Myanmar to Bangladesh following violence in Rakhine state, Myanmar
:: 156,000 are located in makeshift settlement/camps, 35 000 in host communities and 188 000 in new spontaneous settlements
:: 26,747 people have been displaced in Myanmar…
SITUATION OVERVIEW [excerpt]
:: WHO and UNICEF to support MOH on routine EPI and mass vaccination…
Public health concerns  [excerpt]
:: Routine vaccination rates are reported to be very low in northern Rakhine state (e.g. <70% coverage against measles 1 or 2), a reflection of a higher risk of outbreaks from expanded program on immunization-associated diseases…

WHO European Region EURO
:: Day 4 highlights: partnerships essential in our “multisectoral, multidimensional world” 14-09-2017
:: Day 3 highlights: “The health workforce is the beating heart of any health system” 13-09-2017
:: Day 2 highlights: Director-General outlines key health priorities 12-09-2017
:: Day 1 highlights: RC67 opens 11-09-2017
:: 67th session of WHO Regional Committee for Europe opens in Budapest 10-09-2017

WHO Eastern Mediterranean Region EMRO
:: WHO trains 2800 health care providers to respond to gender-based violence
13 September 2017 – WHO estimates that globally around 1 in 3 women have experienced either physical and/or sexual intimate partner violence or non-partner sexual violence. In Afghanistan, WHO, with the support of USAID and the Italian Development Cooperation, has trained over 2800 nurses, doctors and midwives on the gender-based violence protocol, which was developed by the Ministry of Public Health and WHO, with the support of UN Women in 2014. A further 6500 health care providers in all provinces are currently being trained on how to properly manage cases of gender-based violence, including physical, sexual and psychological violence…

CDC/ACIP [to 16 September 2017]

CDC/ACIP [to 16 September 2017]
http://www.cdc.gov/media/index.html

MMWR News Synopsis for September 14, 2017
:: Use of Unannounced Mystery Patient Drills to Assess Hospital Emergency Department Preparedness for Communicable Diseases of Public Health Concern — New York City, 2016
:: Rates and Trends of Pediatric Acute Lymphoblastic Leukemia — United States, 2001–2014
:: Occupational Animal Exposure Among Persons with Campylobacteriosis and Cryptosporidiosis Nebraska, 2005–2015
:: Updated Dosing Instructions for Immune Globulin (Human) GamaSTAN S/D for Hepatitis A Virus Prophylaxis

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State Health Officials Strongly Encourage Influenza Vaccinations Among Pregnant Women
Association of State and Territorial Health Officials [U.S.]
ARLINGTON, Va., Sept. 14, 2017 /PRNewswire-USNewswire/ — Jay Butler, MD, ASTHO president and chief medical officer for the Alaska Department of Health and Social Services, released the following statement today regarding the importance of influenza vaccinations for pregnant women:
“As we enter flu season, state and territorial health officials strongly encourage all individuals six months or older to receive an annual influenza vaccination, including pregnant women and older adults. Each year, millions of Americans are affected by the flu and influenza vaccines are vital to reduce the chances of getting sick. Illness from influenza infection can be particularly dangerous for pregnant women and their developing babies.

A recent report from the ongoing Vaccine Safety Datalink project found that there may be a possible link between miscarriage early in pregnancy and the flu vaccine in women who received a certain version of the vaccine two years in a row. ASTHO and its members are concerned about this potential risk when weighed against other risks, including the risks posed by influenza during pregnancy, and continue to work with national healthcare organizations, including the American College of Obstetricians and Gynecologists and CDC, to determine whether these new findings should lead to any changes in national recommendations. Given the large volume of data indicating the safety of influenza vaccination during pregnancy, ASTHO and its members support current recommendations for use of vaccines during pregnancy.

This study raises an important question about risk, and an ongoing investigation to study this issue further is recommended. It is also important to note that this study does not prove that flu vaccine was the cause of the miscarriage. Earlier studies have not found a link between flu vaccination and miscarriage. CDC continues to recommend that pregnant women get an influenza vaccine during any trimester of their pregnancy because flu poses a danger to pregnant women, and a flu vaccine can prevent influenza in pregnant women which also protects their baby after birth.

State and territorial health departments continue to encourage pregnant women to get vaccinated to be protected from influenza during pregnancy. Immunizations are a vital public health tool and one of the most cost-effective means of public health promotion and disease prevention. Vaccines prevent disease, disability, and death in children and adults.”

Announcements  

Announcements
 
 BMGF – Gates Foundation  [to 16 September 2017]
http://www.gatesfoundation.org/Media-Center/Press-Releases
SEPTEMBER 13, 2017
New Gates Foundation Report Highlights Remarkable Progress Against Global Poverty and Disease, Warns Future Progress in Jeopardy
Bill and Melinda Gates Call for Strong Leadership to Address “Solvable Human Misery”
[See Week in Review above for more detail]
 
CEPI – Coalition for Epidemic Preparedness Innovations  [to 16 September 2017]
http://cepi.net/
[Undated]
Board member advert
CEPI is now looking for visionary leaders to serve on its new permanent Board and help guide the coalition through its next phase of growth, maximising the positive impact that CEPI can make in the years ahead.
To express your interest in being a member of CEPI’s board, or to nominate an individual you believe to be an exceptional candidate, please email board@cepi.net by October 1, 2017, providing a CV where possible.
PDF FORMAT – 50KB  Download

European Medicines Agency  [to 16 September 2017]
http://www.ema.europa.eu/ema/
15/09/2017
Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 11 to 14 September 2017
Thirteen medicines recommended for approval, including one orphan medicine

12/09/2017
Raising awareness of the perils of antimicrobial resistance
EMA to host a meeting with key stakeholders on the work of international health authorities and how to optimise collaboration …
 
FDA [to 16 September 2017]
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/default.htm
What’s New in Biologics
Influenza Virus Vaccine for the 2017-2018 Season
Updated: 9/14/2017
 
Fondation Merieux  [to 16 September 2017]
http://www.fondation-merieux.org/
September 14, 2017
The Mérieux Fondation is celebrating 50 years of fighting infectious diseases in developing countries
Les Pensiéres Center for Global Health, Veyrier-du-Lac (France)
[See Milestones above for more detail
 
Global Fund [to 16 September 2017]
http://www.theglobalfund.org/en/news/?topic=&type=NEWS;&country=
News
22 Million Lives Saved
13 September 2017
Programs supported by the Global Fund to Fight AIDS, Tuberculosis and Malaria have saved 22 million lives, according to a report released today. The report also shows significant increases in the number of people receiving treatment for HIV, diagnosis and treatment for TB and having an insecticide treated net to prevent malaria…
The Global Fund Results Report 2017, with cumulative results through the end of 2016, shows a decline of one-third in the number of people dying from AIDS, TB and malaria in the countries where the Global Fund invests…
Programs supported by the Global Fund, which are designed and implemented by local experts and communities affected by the diseases, provided 11 million people with antiretroviral therapy for HIV – more than half the total number of people on treatment worldwide.
Global Fund-supported programs have provided 17.4 million people with testing and treatment for TB, and 795 million mosquito nets to prevent malaria. As a result of prevention and control interventions in more than 100 countries, the Global Fund’s target of averting 140-180 million infections by the end of 2016 was met in 2015…
Report pdf [52 pages]:
https://www.theglobalfund.org/media/6773/corporate_2017resultsreport_report_en.pdf
 
NIH  [to 16 September 2017]
http://www.nih.gov/news-events/news-releases
September 12, 2017
NIH awards $15 million to support development of 3-D human tissue models
“Tissue chips” to be engineered to model disease and test drug efficacy prior to clinical trials.

Dr. James Ostell named Director of the National Center for Biotechnology Information
September 11, 2017 — NCBI maintains biomedical databases, including PubMed, GenBank, BLAST, Entrez, RefSeq, dbSNP, PubMed Central and dbGaP.
 
PATH  [to 16 September 2017]
http://www.path.org/news/index.php
Announcement | September 14, 2017
PATH joins world leaders in New York City this week to advocate for innovation to create a healthier, more secure world

Announcement | September 11, 2017
PATH announces new collaboration to advance maternal immunization in low- and middle-income countries
[See Milestones above for more details]

UNAIDS [to 16 September 2017]
http://www.unaids.org/en
Update
Thailand launches new national strategy to end the AIDS epidemic by 2030
15 September 2017
The Ministry of Public Health of Thailand has launched its new 2017–2030 National AIDS Strategy, which provides a road map for ending the AIDS epidemic as a public health threat in Thailand by 2030. Narong Pipatanasai, Deputy Prime Minister and Chair of the National AIDS Committee, led the launch at the Government Complex in Bangkok, Thailand, on 13 September.
The 13-year plan adapts the latest global commitments to Thailand, ensuring an effective, cost-efficient and high-impact HIV response. A recent UNAIDS report on the global AIDS epidemic finds that annual new HIV infections dropped by 50% in Thailand between 2010 and 2016, the steepest decline for any country in the Asia and the Pacific region…

Update
UNAIDS and Malaysia launch joint data web platform
14 September 2017
UNAIDS and the Ministry of Health of Malaysia have launched a joint web platform that aims to strengthen the generation of strategic information and the use of national, subnational and key population data for evidence-informed programming.
The platform, which is hosted and supported by the UNAIDS regional data hub, was launched by Noor Hisham Abdullah, Director-General of Malaysia’s Ministry of Health, and Eamonn Murphy, Director of the UNAIDS Regional Support Team for Asia and the Pacific, at the 5th Asia Pacific Conference on Public Health, which ended on 13 September in Kuching, Malaysia…

Update
Metro Manila city leaders commit to intensifying HIV response
11 September 2017
Mayors and other city leaders from the 17 cities that make up the National Capital Region in the Philippines pledged to make the HIV epidemic a public health emergency requiring multisectoral strategies and a full provision of resources. The city representatives recently signed a city HIV resolution during a dinner meeting in Manila hosted by the Secretary of the Department of Health, Paulyn Jean Rosell-Ubial…
 
Wellcome Trust  [to 16 September 2017]
https://wellcome.ac.uk/news
News / Published: 12 September 2017
European foundations unite to tackle global challenges
Three of Europe’s biggest philanthropic foundations have joined together to award €5m to tackle some of the most pressing global challenges of our time.
Wellcome Trust, Volkswagen Stiftung and Riksbankens Jubileumsfond have funded six research groups as part of the Europe and Global Challenges Initiative. The projects range from understanding how to best protect and integrate Syrian refugees, to strengthening climate action in the global south. Each partner will fund two projects directly.
 
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DCVMN – Developing Country Vaccine Manufacturers Network  [to 16 September 2017]
http://www.dcvmn.org/
25 September 2017 to 28 September 2017
DCVMN Annual General Meeting
Seoul / Korea
Download the Agenda
 
 
Industry Watch
:: FDA Advisory Committee votes unanimously for Shingrix (HZ/su) in the US for prevention of herpes zoster (shingles) in adults ages 50 and over
LONDON, Sept. 13, 2017 /PRNewswire/ — GlaxoSmithKline plc announced today that the Vaccines and Related Biological Products Advisory Committee (VRBPAC) of the US Food and Drug Administration (FDA) voted unanimously that the data support the efficacy and safety of Shingrix, for the prevention of herpes zoster (shingles) in adults ages 50 and over. FDA Advisory Committees provide non-binding recommendations for consideration by the FDA, with the final decision on approval made by the FDA.
Dr. Emmanuel Hanon, Senior Vice President and Head of Vaccines R&D for GSK said: “Shingles is a painful and potentially serious condition. The risk of developing shingles increases with age and it is estimated that up to one in three people in the United States will develop shingles. Today’s vote brings us one step closer to approval of Shingrix, which is specifically designed to overcome age-related weakening of the immune system.”
The Biologics License Application (BLA) was submitted to the FDA in October 2016…
 

Journal Watch

Journal Watch

   Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focus on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.

If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org