Health Equity in US Latinx Communities

AMA Journal of Ethics
Volume 24, Number 4: E249-341 Apr 2022
https://journalofethics.ama-assn.org/issue/health-equity-us-latinx-communities

 

Health Equity in US Latinx Communities
Latinx communities in the US include over 60 million people with a plurality of political beliefs, cultural practices, and wealth. This diversity is also expressed in population health data: some health indicators suggest advantages of Latinx community membership while other data demonstrate inequitable disease burden and maldistribution of environmental and occupational risk. Legacies of colonial conquest of the Americas persist in discrimination and marginalization today and are embodied by members of our Latinx communities.

The impact of COVID-19 vaccination on case fatality rates in a city in Southern Brazil

American Journal of Infection Control
May 2022 Volume 50 Issue 5 p477-592
http://www.ajicjournal.org/current

 

Major Articles
The impact of COVID-19 vaccination on case fatality rates in a city in Southern Brazil
Hisrael Passarelli-Araujo, Henrique Pott-Junior, Aline M. Susuki,…Michael Aschner, Monica M.B. Paoliello, Mariana R. Urbano
Published online: February 19, 2022
p491-496

Influenza vaccination coverage among adults by nativity, race/ethnicity, citizenship, and language of the interview – United States, 2012-2013 through 2017-2018 influenza seasons

American Journal of Infection Control
May 2022 Volume 50 Issue 5 p477-592
http://www.ajicjournal.org/current

 

Influenza vaccination coverage among adults by nativity, race/ethnicity, citizenship, and language of the interview – United States, 2012-2013 through 2017-2018 influenza seasons
Meagan R. Chuey, Mei-Chuan Hung, Anup Srivastav,…Kimberly H. Nguyen, Walter W. Williams, Alfonso Rodriguez Lainz
Published online: September 11, 2021
p497-502

Mask use among health care workers and feelings of safety at work pre- and post- COVID-19 vaccine

American Journal of Infection Control
May 2022 Volume 50 Issue 5 p477-592
http://www.ajicjournal.org/current

 

Mask use among health care workers and feelings of safety at work pre- and post- COVID-19 vaccine
Laura S. O’Donohue, Susan Fletcher-Gutowski, Amreetpal Sidhu, Aishwarya Verma, Tarin C. Phillips,
Preeti G. Misra
Published online: November 15, 2021
p503-508

Racial and ethnic differences in vaccine hesitancy Among registered nurses in New Jersey: A cross-sectional survey

American Journal of Infection Control
May 2022 Volume 50 Issue 5 p477-592
http://www.ajicjournal.org/current

 

Brief Reports
Racial and ethnic differences in vaccine hesitancy Among registered nurses in New Jersey: A cross-sectional survey
Irina B. Grafova, Monika Pogorzelska-Maziarz, Mary L. Johansen, Mary Lou Manning, Suzanne Crincoli,
Pamela B. de Cordova
Published online: February 11, 2022
p572-574

COVID-19 Vaccine Uptake Among Nursing Home Staff via Statewide Policy: The Mississippi Vaccinate or Test Out Policy

American Journal of Public Health
May 2022 112(5)
http://ajph.aphapublications.org/toc/ajph/current

 

Articles
COVID-19 Vaccine Uptake Among Nursing Home Staff via Statewide Policy: The Mississippi Vaccinate or Test Out Policy
Immunization/Vaccines, Health Policy, Aging
Maggie L. Syme, Natalia Gouskova and Sarah D. Berry

Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

Annals of Internal Medicine
May 2022 Volume 175, Issue 5
http://annals.org/aim/issue

 

Reviews
Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points
FREE
Anjum S. Kaka, MD, Roderick MacDonald, MS, Eric J. Linskens, BS, Lisa Langsetmo, PhD, … et al.
Pages:701–709

Acceptance of COVID-19 vaccine and determinant factors in the Iranian population: a web-based study

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
(Accessed 21 May 2022)

 

Acceptance of COVID-19 vaccine and determinant factors in the Iranian population: a web-based study
Iran had a high rate of death in several COVID 19 waves. Vaccination is a method for prevention and control of the COVID-19 pandemic. Success in controlling the pandemic is not solely dependent on the effectiv…
Authors: Shabnam Omidvar and Mojgan Firouzbakht
Citation: BMC Health Services Research 2022 22:652
Content type: Research Published on: 16 May 2022

Economic assessment of incorporating the hexavalent vaccine as part of the National Immunization Program of Peru

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
(Accessed 21 May 2022)

 

Economic assessment of incorporating the hexavalent vaccine as part of the National Immunization Program of Peru
This study aimed to estimate the economic impact of replacing the current Peruvian primary immunization scheme for infants under 1 year old with an alternative scheme with similar efficacy, based on a hexavale…
Authors: Janice Seinfeld, María Laura Rosales, Alfredo Sobrevilla and Juan Guillermo López Yescas
Citation: BMC Health Services Research 2022 22:651
Content type: Research Published on: 16 May 2022

Testing and vaccination to reduce the impact of COVID-19 in nursing homes: an agent-based approach

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 21 May 2022)

 

Testing and vaccination to reduce the impact of COVID-19 in nursing homes: an agent-based approach
Efforts to protect residents in nursing homes involve non-pharmaceutical interventions, testing, and vaccine. We sought to quantify the effect of testing and vaccine strategies on the attack rate, length of th…
Authors: José P. Gómez Vázquez, Yury E. García, Alec J. Schmidt, Beatriz Martínez-López and Miriam Nuño
Citation: BMC Infectious Diseases 2022 22:477
Content type: Research Published on: 19 May 2022

Adverse effects following COVID-19 vaccination in Iran

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 21 May 2022)

 

Adverse effects following COVID-19 vaccination in Iran
Vaccination is a key intervention to prevent COVID-19. Many vaccines are administered globally, yet there is not much evidence regarding their safety and adverse effects. Iran also faces this challenge, especi…
Authors: Ebrahim Babaee, Ali Amirkafi, Arash Tehrani-Banihashemi, Neda SoleimanvandiAzar, Babak Eshrati, Zahra Rampisheh, Mehran Asadi-Aliabadi and Marzieh Nojomi
Citation: BMC Infectious Diseases 2022 22:476
Content type: Research Published on: 18 May 2022

Acceptance of COVID-19 vaccination and influencing factors among people living with HIV in Guangxi, China: a cross-sectional survey

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 21 May 2022)

 

Acceptance of COVID-19 vaccination and influencing factors among people living with HIV in Guangxi, China: a cross-sectional survey
Vaccination has been proven to be an effective approach against the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to determine the acceptance rate and factors influencing acceptance of COVID-1…
Authors: Jinming Su, Zhenwei Jia, Xinwei Wang, Fengxiang Qin, Rongfeng Chen, Yuting Wu, Beibei Lu, Chunlin Lan, Tongxue Qin, Yinlu Liao, Minjuan Shi, Yanyan Liao, Peijiang Pan, Li Ye, Junjun Jiang and Hao Liang
Citation: BMC Infectious Diseases 2022 22:471
Content type: Research Published on: 16 May 2022

Patient consent preferences on sharing personal health information during the COVID-19 pandemic: “the more informed we are, the more likely we are to help”

BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 21 May 2022)

 

Patient consent preferences on sharing personal health information during the COVID-19 pandemic: “the more informed we are, the more likely we are to help”
Authors: Sarah Tosoni, Indu Voruganti, Katherine Lajkosz, Shahbano Mustafa, Anne Phillips, S. Joseph Kim, Rebecca K. S. Wong, Donald Willison, Carl Virtanen, Ann Heesters and Fei-Fei Liu
Content type: Research 20 May 2022

An assessment of the vaccination of school-aged children in England against SARS-CoV-2

BMC Medicine
http://www.biomedcentral.com/bmcmed/content
(Accessed 21 May 2022)

 

An assessment of the vaccination of school-aged children in England against SARS-CoV-2
Children and young persons are known to have a high number of close interactions, often within the school environment, which can facilitate rapid spread of infection; yet for SARS-CoV-2, it is the elderly and …
Authors: Matt J. Keeling and Sam E. Moore
Citation: BMC Medicine 2022 20:196
Content type: Research article Published on: 18 May 2022

Perceptions of the Coronavirus and COVID-19 testing and vaccination in Latinx and Indigenous Mexican immigrant communities in the Eastern Coachella Valley

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 21 May 2022)

 

Perceptions of the Coronavirus and COVID-19 testing and vaccination in Latinx and Indigenous Mexican immigrant communities in the Eastern Coachella Valley
A novel coronavirus, SARS-CoV-2 (known as COVID-19), spread rapidly around the world, affecting all and creating an ongoing global pandemic. Across the United States, Latinx and Indigenous populations have bee…
Authors: Daniel Gehlbach, Evelyn Vázquez, Gabriela Ortiz, Erica Li, Cintya Beltrán Sánchez, Sonia Rodríguez, María Pozar and Ann M. Cheney
Citation: BMC Public Health 2022 22:1019
Content type: Research Published on: 21 May 2022

Public health and social measures to mitigate the health and economic impact of the COVID-19 pandemic in Turkey, Egypt, Ukraine, Kazakhstan, and Poland during 2020–2021: situational analysis

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 21 May 2022)

 

Public health and social measures to mitigate the health and economic impact of the COVID-19 pandemic in Turkey, Egypt, Ukraine, Kazakhstan, and Poland during 2020–2021: situational analysis
The COVID-19 pandemic had a colossal impact on human society globally. There were similarities and differences in the public health and social measures taken by countries, and comparative analysis facilitates …
Authors: Noriko Kitamura, Kaja Abbas and Dilip Nathwani
Citation: BMC Public Health 2022 22:991
Content type: Research Published on: 17 May 2022

Trinity review: integrating Registered Reports with research ethics and funding reviews

BMC Research Notes
http://www.biomedcentral.com/bmcresnotes/content
(Accessed 21 May 2022)

 

Trinity review: integrating Registered Reports with research ethics and funding reviews
One major source of exhaustion for researchers is the redundant paperwork of three different documents—research papers, ethics review applications, and research grant applications—for the same research plan. T…
Authors: Yuki Mori, Kaito Takashima, Kohei Ueda, Kyoshiro Sasaki and Yuki Yamada
Citation: BMC Research Notes 2022 15:184
Content type: Commentary Published on: 19 May 2022
Abstract
One major source of exhaustion for researchers is the redundant paperwork of three different documents—research papers, ethics review applications, and research grant applications—for the same research plan. This is a wasteful and redundant process for researchers, and it has a more direct impact on the career development of early-career researchers. Here, we propose a trinity review system based on Registered Reports that integrates scientific, ethics, and research funding reviews. In our proposed trinity review system, scientific and ethics reviews are undertaken concurrently for a research protocol before running the study. After the protocol is approved in principle through these review processes, a funding review will take place, and the researchers will begin their research. Following the experiments or surveys, the scientific review will be conducted on a completed version of the paper again, including the results and discussions (i.e., the full paper), and the full paper will be published once it has passed the second review. This paper provides the brief process of the trinity review system and discusses the need for and benefits of the proposed system. Although the trinity review system only applies to a few appropriate disciplines, it helps improve reproducibility and integrity.

Improving research integrity: a framework for responsible science communication

BMC Research Notes
http://www.biomedcentral.com/bmcresnotes/content
(Accessed 21 May 2022)

 

Improving research integrity: a framework for responsible science communication
Research integrity, an essential precept of scientific inquiry and discovery, comprises norms such as Rigor, Reproducibility, and Responsibility (the 3R’s). Over the past decades, numerous issues have arisen that challenge the reliability of scientific studies, including irreproducibility crises, lack of good scientific principles, and erroneous communications, which have impacted the public’s trust in science and its findings. Here, we highlight one important component of research integrity that is often overlooked in the discussion of proposals for improving research quality and promoting robust research; one that spans from the lab bench to the dissemination of scientific work: responsible science communication.
Authors: Ilinca I. Ciubotariu and Gundula Bosch
Citation: BMC Research Notes 2022 15:177
Content type: Commentary Published on: 15 May 2022

Precision medicine requires understanding how both sex and gender influence health

Cell
May 12, 2022 Volume 185 Issue 10 p1619-1806
https://www.cell.com/cell/current

 

Commentary
Precision medicine requires understanding how both sex and gender influence health
Nina S. Stachenfeld, Carolyn M. Mazure
Progress in studying sex as a biological variable (SABV) is slow, and the influence of gendered effects of the social environment on biology is largely unknown. Yet incorporating these concepts into basic science research will enhance our understanding human health and disease. We provide steps to move this process forward.

COVID-19 vaccines in patients with decompensated cirrhosis: a retrospective cohort on safety data and risk factors associated with unvaccinated status

Infectious Diseases of Poverty
http://www.idpjournal.com/content
[Accessed 21 May 2022]

 

COVID-19 vaccines in patients with decompensated cirrhosis: a retrospective cohort on safety data and risk factors associated with unvaccinated status
Safety data reported from the large-scale clinical trials of the coronavirus disease 2019 (COVID-19) vaccine are extremely limited in patients with decompensated cirrhosis. The vaccination campaign in this spe…
Authors: Zhujun Cao, Chenxi Zhang, Shuang Zhao, Zike Sheng, Xiaogang Xiang, Ruokun Li, Zhuping Qian, Yinling Wang, Bin Chen, Ziqiang Li, Yuhan Liu, Baoyan An, Huijuan Zhou, Wei Cai, Hui Wang, Honglian Gui…
Citation: Infectious Diseases of Poverty 2022 11:56
Content type: Research Article Published on: 16 May 2022

Could China’s journey of malaria elimination extend to Africa?

Infectious Diseases of Poverty
http://www.idpjournal.com/content
[Accessed 21 May 2022]

 

Could China’s journey of malaria elimination extend to Africa?
World Health Organization (WHO) certified China malaria-free on June 30, 2021, which brightens the goal of global malaria elimination efforts. China contributed its unique innovations to the global community: …
Authors: Duoquan Wang, Shan Lv, Wei Ding, Shenning Lu, Hongwei Zhang, Kokouvi Kassegne, Shang Xia, Lei Duan, Xuejiao Ma, Lulu Huang, Roly Gosling, Joshua Levens, Salim Abdulla, Mutinta Mudenda, Moses Okpeku, Kenneth Kamwi Matengu…
Citation: Infectious Diseases of Poverty 2022 11:55
Content type: Opinion Published on: 16 May 2022

The impact of pertussis vaccine programme changes on pertussis disease burden in Manitoba, 1992–2017—an age-period-cohort analysis

International Journal of Epidemiology
Volume 51, Issue 2, April 2022
https://academic.oup.com/ije/issue

 

Infectious Disease
The impact of pertussis vaccine programme changes on pertussis disease burden in Manitoba, 1992–2017—an age-period-cohort analysis
Krista Wilkinson, Christiaan H Righolt, Lawrence J Elliott, Sergio Fanella, Salaheddin M Mahmud
International Journal of Epidemiology, Volume 51, Issue 2, April 2022, Pages 440–447, https://doi.org/10.1093/ije/dyac001

Association Between SARS-CoV-2 Viral Load in Wastewater and Reported Cases, Hospitalizations, and Vaccinations in Milan, March 2020 to November 2021

JAMA
May 17, 2022, Vol 327, No. 19, Pages 1849-1936
https://jamanetwork.com/journals/jama/currentissue

 

Research Letter
Association Between SARS-CoV-2 Viral Load in Wastewater and Reported Cases, Hospitalizations, and Vaccinations in Milan, March 2020 to November 2021
Giovanni Nattino, PhD; Sara Castiglioni, PhD; Danilo Cereda, MD, PhD; et al.
free access
JAMA. 2022;327(19):1922-1924. doi:10.1001/jama.2022.4908
This study evaluates the association between SARS-CoV-2 load in urban wastewater and surveillance indicators of infection prevalence and severity in Milan, Italy.

Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical ResearchThe PRO Ethics Guidelines

JAMA
May 17, 2022, Vol 327, No. 19, Pages 1849-1936
https://jamanetwork.com/journals/jama/currentissue

 

Special Communication
Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical ResearchThe PRO Ethics Guidelines
Samantha Cruz Rivera, PhD; Olalekan Lee Aiyegbusi, PhD; Jonathan Ives, PhD; et al.
free access has active quiz has audio
JAMA. 2022;327(19):1910-1919. doi:10.1001/jama.2022.6421
These international, consensus-based, patient-reported outcomes (PRO)–specific guidelines aim to lay out the ethical considerations that researchers, research ethics committees, and funders should take into account when conducting or reviewing PRO clinical research.

COVID-19 Vaccination—Becoming Part of the New Normal

JAMA
May 17, 2022, Vol 327, No. 19, Pages 1849-1936
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
COVID-19 Vaccination—Becoming Part of the New Normal
Peter Marks, MD, PhD; Janet Woodcock, MD; Robert Califf, MD
free access
JAMA. 2022;327(19):1863-1864. doi:10.1001/jama.2022.7469
In this Viewpoint, authors from the FDA discuss how COVID-19 vaccination is an integral part of establishing a new normal, now that SARS-CoV-2, the virus that causes COVID-19, will likely circulate worldwide for the foreseeable future.

Willingness of a Multiethnic Immigrant Population to Donate Biospecimens for Research Purposes

Journal of Immigrant and Minority Health
Volume 24, issue 3, June 2022
https://link.springer.com/journal/10903/volumes-and-issues/24-3

 

Contents
Willingness of a Multiethnic Immigrant Population to Donate Biospecimens for Research Purposes
Authors (first, second and last of 12)
Amy Raines-Milenkov, Martha Felini, Jonathan Hughes
Content type: Original Paper
Open Access
Published: 26 July 2021
Pages: 705 – 712

Nativity Differences in Awareness and Knowledge About HPV Infection and Vaccination Among U.S. Adults: Findings from a National Population-Based Sample

Journal of Immigrant and Minority Health
Volume 24, issue 3, June 2022
https://link.springer.com/journal/10903/volumes-and-issues/24-3

 

Nativity Differences in Awareness and Knowledge About HPV Infection and Vaccination Among U.S. Adults: Findings from a National Population-Based Sample
Authors
Manami Bhattacharya, Serena Xiong, Annie-Laurie McRee
Content type: Brief Communication
Published: 28 August 2021
Pages: 794 – 798

Introduction to Special Issue: Gender, Migration and Digital Communication in Asia

Journal of Immigrant & Refugee Studies
Volume 20, 2022 Issue 2
https://www.tandfonline.com/toc/wimm20/current

 

Article
Introduction to Special Issue: Gender, Migration and Digital Communication in Asia
Shiori Shakuto & Brenda S. A. Yeoh
Pages: 155-163
Published online: 15 Apr 2022
Abstract
In recent decades, the role of digital communication in the lives of migrants in Asia has greatly expanded, becoming integral to the decision to migrate, earning a living, and the practice of keeping in touch with left-behind families and friends. The papers in this Special Issue foreground how gender structures and practices within migrant households and the wider political economy shape migrants’ digital communications. They expand the breadth of our thinking about the interlinkages among gender, migration and digital communication from a range of new subject positions including transnational families, international students, and marginalized minorities in the region.

The Ethics of Human Challenge Trials Using Emerging Severe Acute Respiratory Syndrome 2 VariantsGet access

Journal of Infectious Diseases
Volume 225, Issue 6, 15 March 2022
https://academic.oup.com/jid/issue/225/6

 

PERSPECTIVES
The Ethics of Human Challenge Trials Using Emerging Severe Acute Respiratory Syndrome 2 VariantsGet access
Abie Rohrig, Nir Eyal
The Journal of Infectious Diseases, Volume 225, Issue 6, 15 March 2022, Pages 934–937, https://doi.org/10.1093/infdis/jiab488
Researchers are preparing for human challenge trials with emerging SARS-CoV-2 variants. We argue that these trials can be ethical.

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

The Lancet
May 21, 2022 Volume 399 Number 10339 p1917-1990
https://www.thelancet.com/journals/lancet/issue/current

 

Articles
Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses
WHO Solidarity Trial Consortium
Open Access
Background
The Solidarity trial among COVID-19 inpatients has previously reported interim mortality analyses for four repurposed antiviral drugs. Lopinavir, hydroxychloroquine, and interferon (IFN)-β1a were discontinued for futility but randomisation to remdesivir continued. Here, we report the final results of Solidarity and meta-analyses of mortality in all relevant trials to date.
Interpretation
Remdesivir has no significant effect on patients with COVID-19 who are already being ventilated. Among other hospitalised patients, it has a small effect against death or progression to ventilation (or both).

Framing and the formation of global health priorities

The Lancet
May 21, 2022 Volume 399 Number 10339 p1917-1990
https://www.thelancet.com/journals/lancet/issue/current

 

Series
Political Science and Health
Framing and the formation of global health priorities
Jeremy Shiffman, Yusra Ribhi Shawar
Summary
Health issues vary in the amount of attention and resources they receive from global health organisations and national governments. How issues are framed could shape differences in levels of priority. We reviewed scholarship on global health policy making to examine the role of framing in shaping global health priorities. The review provides evidence of the influence of three framing processes—securitisation, moralisation, and technification. Securitisation refers to an issue’s framing as an existential threat, moralisation as an ethical imperative, and technification as a wise investment that science can solve. These framing processes concern more than how issues are portrayed publicly. They are socio-political processes, characterised by contestation among actors in civil society, government, international organisations, foundations, and research institutions. These actors deploy various forms of power to advance particular frames as a means of securing attention and resources for the issues that concern them. The ascription of an issue as a security concern, an ethical imperative, or a wise investment is historically contingent: it is not inevitable that any given issue will be framed in one or more of these ways. A health issue’s inherent characteristics—such as the lethality of a pathogen that causes it—also shape these ascriptions, but do not fully determine them. Although commonly facing resistance, global health elites often determine which frames prevail, raising questions about the legitimacy of priority-setting processes. We draw on the review to offer ideas on how to make these processes fairer than they are at present, including a call for democratic representation even as necessary space is preserved for elite expertise.

Polygenic risk scores for CARDINAL study

Nature Genetics
Volume 54 Issue 5, May 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Comment | 05 May 2022
Polygenic risk scores for CARDINAL study
The Cardiometabolic Disorders in African-Ancestry Populations (CARDINAL) study site is a well-powered, first-of-its-kind resource for developing, refining and validating methods for research into polygenic risk scores that accounts for local ancestry, to improve risk prediction in diverse populations.
Clement A. Adebamowo, Adebowale Adeyemo, Sally N. Adebamowo

Promoting the genomic revolution in Africa through the Nigerian 100K Genome Project

Nature Genetics
Volume 54 Issue 5, May 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Comment | 09 May 2022
Promoting the genomic revolution in Africa through the Nigerian 100K Genome Project
To leverage the genetic diversity in Nigeria, we established the Non-Communicable Diseases Genetic Heritage Study (NCD-GHS) consortium to help produce a comprehensive catalog of human genetic variation in Nigeria and assess the burden and etiological characteristics of non-communicable diseases in 100,000 adults in Nigeria.
Segun Fatumo, Aminu Yakubu, Abasi Ene-Obong

Walking the tightrope between data sharing and data protection

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Editorial | 18 May 2022
Walking the tightrope between data sharing and data protection
With the increase in genomic data available and the advent of new technology for mining it, balancing the needs for data sharing and data protection becomes more challenging. Different disciplines must come together to find new solutions.

The distinct impacts of race and genetic ancestry on health

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Comment | 09 May 2022
The distinct impacts of race and genetic ancestry on health
Genetic ancestry affects human health, but this is distinct from the impact of race, a social construct that has its foundations in systemic racism. These terms need to be better defined and understood in medical research to achieve health equity.
Timothy R. Rebbeck, Brandon Mahal, Kosj Yamoah

An equitable roadmap for ending the COVID-19 pandemic

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Comment | 05 April 2022
An equitable roadmap for ending the COVID-19 pandemic
Many governments are rolling back restrictions, but the pandemic will end only with a renewed focus on equitable distribution of vaccines and therapeutics, responsive public health plans, and policies to protect the vulnerable.
Mitsuru Mukaigawara, Ines Hassan, Devi Sridhar

Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Brief Communication | 24 February 2022 | Open Access
Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India
A multi-scale model using population-level transmission and individual-level vaccination data suggests that vaccine dose fractionation could be a cost-effective strategy for mitigating the COVID-19 pandemic in India.
Zhanwei Du, Lin Wang, Benjamin J. Cowling

Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Article | 03 March 2022 | Open Access
Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial
A third dose of the COVID-19 vaccine mRNA-1273 is safe and boosts SARS-CoV-2 neutralizing antibody titers almost two-fold higher than the peak levels observed after completion of a two-dose series, highlighting the potential clinical benefit of a booster dose.
Laurence Chu, Keith Vrbicky, Roderick McPhee

Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Article | 21 February 2022 | Open Access
Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants
A test-negative case–control analysis using data from a diverse population in California, USA, demonstrates that vaccine efficacy of a three-dose regimen of the mRNA-1273 COVID-19 vaccine is reduced against infection with the Omicron SARS-CoV-2 variant in comparison to Delta, but that efficacy against hospitalization remained high for both variants.
Hung Fu Tseng, Bradley K. Ackerson, Lei Qian

Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

Nature Medicine
Volume 28 Issue 5, May 2022
https://www.nature.com/nm/volumes/28/issues/5

 

Article | 14 February 2022 | Open Access
Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
A large study in the United Kingdom shows that virus-specific antibody levels associated with at least 67% protection against SARS-CoV-2 Delta variant infection last longer after two doses of BNT162b2 vaccine than after two doses of ChAdOx1 vaccine in previously uninfected individuals.
Jia Wei, Koen B. Pouwels, Chris Cunningham