Public Health Emergency of International Concern (PHEIC)
Polio this week as of 13 March 2018 [GPEI]
::  New on www.polioeradication.org: For International Women’s Day, we highlighted the critical role that women play in global polio eradication efforts. Dr Adele Daleke Lisi Aluma works to reach children who have never been vaccinated, whilst in Somalia, women are the face of polio eradication. In Nigeria, dedicated female mobilizers are ending polio, one home at a time.
::  We also launched the Gender and Polio section of our website.
:: The Strategic Advisory Group of Experts on immunization (SAGE) Polio Working Group recently met in Geneva, Switzerland, to review global progress against polio. The group reviewed and endorsed the main elements of the Post-Eradication Strategy (PCS) currently being developed at the request of Member States, aimed at ensuring the availability of core functions to sustain a polio-free world after global certification (such as outbreak response capacity, surveillance, immunization and containment).  The PCS will be presented in April to the full SAGE, and to Member States at the World Health Assembly (WHA) in May. The group also reviewed current outbreak response protocols to vaccine-derived poliovirus, and agreed with a proposed plan to harmonize recommendations on immunization schedules in countries with Polio Essential Facilities (PEFs – facilities that will continue to handle poliovirus stock under appropriate containment).
Summary of newly-reported viruses this week:
Afghanistan: Advance notifications have been received of two new cases of wild poliovirus type 1 (WPV1), one occurring in Kunar province, and one in Kandahar province. Three new wild poliovirus type 1 (WPV1) positive environmental samples have been reported in Nangarhar province.
Pakistan: One new WPV1 positive environmental sample has been reported in Balochistan province.
Democratic Republic of the Congo: Two cases of circulating vaccine-derived poliovirus type 2 (cVDPV2) reported, one from Tanganyika province, and one from Haut Lomami province.

WHO Grade 3 Emergencies  [to 17 March 2018]
:: Seven years of Syria’s health tragedy
News release       14 March 2018 | Geneva – After seven years of conflict in Syria, WHO has renewed its call for the protection of health workers and for immediate access to besieged populations.
Attacks on the health sector have continued at an alarming level in the past year. The 67 verified attacks on health facilities, workers, and infrastructure recorded during the first two months of 2018 amount to more than 50% of verified attacks in all of 2017.
“This health tragedy must come to an end,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “Every attack shatters communities and ripples through health systems, damaging infrastructure and reducing access to health for vulnerable people. WHO calls on all parties to the conflict in Syria to immediately halt attacks on health workers, their means of transport and equipment, hospitals and other medical facilities.”…

:: Diphtheria vaccination campaign for 2.7 million children concludes in Yemen
SANA’A, YEMEN, 16 March 2018
[See Milestones/Perspectives above for more detail]

WHO Grade 2 Emergencies  [to 17 March 2018]
Bangladesh/Myanmar: Rakhine Conflict 2017 
:: Weekly Situation Report #17 – 13 March 2018
… The third round of 13-day Diptheria campaign has started on 10 March. By day 3, 86 497 (21%) children aged 6 weeks to 15 years have been vaccinated in Ukhiya and Teknaf Upazilas. 1479 humanitarian workers have also received Td vaccine at session sites during campaign days.
… A fixed site at Cox’s Bazar has started vaccinating humanitarian workers and will continue every Saturday henceforth.
… Routine EPI training was conducted in Teknaf and Ukhiya to reorient 270 vaccinators, supervisors, medical officers, and volunteers from Government and various NGOs who would be supporting EPI session sites in camps.
… Microplans for routine EPI in Rohingya refugee settings have been developed and EPI services at fixed sites are ongoing…

UN OCHA – L3 Emergencies
The UN and its humanitarian partners are currently responding to three ‘L3’ emergencies. This is the global humanitarian system’s classification for the response to the most severe, large-scale humanitarian crises. 
:: UN Humanitarian Chief and Dutch Minister call for urgent international support to meet spiralling humanitarian needs in DR Congo
(Kinshasa, 13 March 2018) UN humanitarian chief Mark Lowcock and Minister for Foreign Trade and Development Cooperation of the Kingdom of the Netherlands, Sigrid Kaag, today called on the international community to urgently address the crisis facing the Democratic Republic of the Congo (DRC) where humanitarian needs have doubled since last year.
More than 13 million people in DRC need humanitarian assistance and 4.5 million have been forced to flee their homes as a result of fighting. More than 4.6 million Congolese children are acutely malnourished, including 2.2 million cases of severe acute malnutrition. Epidemics are spreading, including the worst outbreak of cholera in 15 years.

Syrian Arab Republic
:: 16 Mar 2018   Update on the situation of children in Afrin and Eastern Ghouta

:: 13 Mar 2018  Yemen Humanitarian Update Covering 05 March – 11 March | Issue 6

UN OCHA – Corporate Emergencies
When the USG/ERC declares a Corporate Emergency Response, all OCHA offices, branches and sections provide their full support to response activities both at HQ and in the field.
:: Ethiopia: Government and partners launch the humanitarian and disaster resilience plan (HDRP) for 2018  13 Mar 2018
US$1.66 billion urgently needed to address food and non-food needs for 7.88 million people
(Addis Ababa, 13 March 2018): The Government of Ethiopia and humanitarian partners today launched the Ethiopia Humanitarian and Disaster Resilience Plan (HDRP) for 2018. The HDRP seeks US$1.66 billion to reach 7.88 million people with emergency food or cash and non-food assistance, mainly in the southern and south-eastern parts of the country. “In the last two years, the Government of Ethiopia, with the support of international donors and humanitarian partners, was able to mount a robust drought response operation. Today, we need that partnership once again as continuing drought, flooding and conflict-related displacement has left 7.88 million vulnerable people in need of urgent assistance”, says Mr. Mitiku Kassa, Commissioner of the National Disaster Risk Management Commission (NDRMC). “The Government of Ethiopia has committed $138 million for drought response and rehabilitation of IDPs,” added the Commissioner…
:: UN allocates $9 million to support life-saving aid in north-east Nigeria
(Abuja, 15 March 2018): The United Nations, through the Nigeria Humanitarian Fund, has allocated US$9 million to provide life-saving aid to some 60,000 children, women and men recently displaced by ongoing hostilities in Borno State, including $2 million in support of the UN Humanitarian Air Service for frontline responders in north-east Nigeria.
The humanitarian crisis in the region remains one of the most severe in the world today, with at least 7.7 million people in need of humanitarian assistance in 2018 in the worst-affected states of Borno, Adamawa and Yobe states. About 80 per cent of them, 6.1 million, are targeted for humanitarian assistance…
Rohinga Refugee Crisis 
:: Joint Response Plan for the Rohingya crisis requests US$951M to provide life-saving assistance to 1.3M people
16 March 2018
A new Joint Response Plan for the Rohingya humanitarian crisis has been launched today in Geneva. It requests US$951 million to provide life-saving assistance to 1.3 million people, including Rohingya refugees who fled Myanmar to Bangladesh and local host communities.
The priority needs in the plan, which covers the March-December 2018 timeframe, include food, water and sanitation, shelter, and medical care…
:: ISCG Situation Report: Rohingya Refugee Crisis, Cox’s Bazar | 11 March 2018

:: Donors agree measures to prevent famine in Somalia in 2018   06 Mar 2018
In support of The Federal Government of Somalia, the United Kingdom and the United Nations Office for the Coordination of Humanitarian Affairs (OCHA) convened an event in London on 6 March 2018 to draw urgent attention to the humanitarian crisis in Somalia and the need for a swift and substantial response…The event was attended by 31 Member States, UN Agencies, international organizations and non-governmental organizations committed to ensuring support for the humanitarian situation in Somalia for 2018…
Editor’s Note:
We will cluster these recent emergencies as below and continue to monitor the WHO webpages for updates and key developments.

MERS-CoV [to 17 March 2018]
:: Middle East respiratory syndrome coronavirus (MERS-CoV) – Oman  15 March 2018
Yellow Fever  [to 17 March 2018]
:: Yellow fever – Brazil  9 March 2018
…WHO risk assessment
The exponential increase in human cases and epizootics during January and February 2018, as indicated in Figure 1, is concerning due to the persistence of high viral circulation in at-risk areas and the spread to new areas, particularly near urban areas of large cities, such as São Paulo and Rio de Janeiro, and in municipalities that were previously not considered at-risk for Yellow fever.

The preliminary results of the mass vaccination campaign in São Paulo and Rio de Janeiro states indicate low vaccination coverage which suggests a significant number of persons remain at-risk and the necessity to intensify risk communications among high-risk groups.

Despite the significant efforts made to vaccinate large portion of the population, the increasing number of human cases and the persistence and geographical spread of epizootics among non-human primates illustrate the potential risk of further spread to new areas within Brazil that were not previously considered as at risk and where therefore yellow fever immunization coverage is low. The seasonality need also to be taken in to account as the outbreak is occurring the period of the year the most favourable for sylvatic yellow fever transmission.

The increasing occurrence of confirmed yellow fever infection also shows the potential of international spread. Although to date most imported cases have been reported in countries where the vector is absent (or absent during winter). These reports illustrate the importance of maintaining high levels of awareness especially for international travellers from areas with favourable ecosystem for yellow fever transmission.

To date, yellow fever transmission by Aedes aegypti has not been documented. The sylvatic yellow fever virus is transmitted to monkeys by forest dwelling mosquitoes such as Haemagogus and Sabethes spp. Humans who are exposed to these mosquitoes can become infected if they are not vaccinated. In entomological studies conducted during the 2016/2017 outbreak in some of the affected states, isolated Haemagogus mosquitoes were found to be positive for yellow fever indicating predominantly sylvatic transmission. More recently, an investigation conducted by the Evandro Chagas Institute reported by the Brazil Ministry of Health revealed the detection of yellow fever virus in Aedes albopictus mosquitoes captured in rural areas of two municipalities in Minas Gerais (Ituêta and Alvarenga) in 2017. The significance of this finding requires further investigation. The last documented outbreak of urban yellow fever in Brazil was recorded in 1942.

WHO continues to monitor the epidemiological situation and review the risk assessment based on the latest available information.

WHO advice
WHO encourage Member States to take all actions necessary to keep travellers well informed of risks and preventive measures including vaccination, and to inform them of the designated specific yellow fever vaccination centres within their territories, in accordance with Annex 7 of the International Health Regulations (2005). Travellers should also be made aware of yellow fever symptoms and signs and instructed to seek rapidly medical advice when presenting signs. Viraemic returning travellers may pose a risk for the establishment of local cycles of yellow fever transmission in areas where the competent vector is present.

Yellow fever can easily be prevented through vaccination. A single dose of WHO approved yellow fever vaccines, administered at least 10 days before travel, is sufficient to confer sustained immunity and life-long protection against the disease, and a booster dose of the vaccine is not needed.

WHO recommends vaccination of international travellers going to Brazil. The updated areas at risk for yellow fever transmission and the related recommendations for vaccination of international travellers were updated by WHO on 16 January 2018; the map of revised areas at risk and yellow fever vaccination recommendations is available on the WHO ITH website: Yellow fever vaccination recommendations in the Americas, 2018

WHO does not recommend that any general travel or trade restriction be applied on Brazil based on the information available for this event.
[See also: CDC Warns Of Deadly Outbreak of Yellow Fever in Brazil – Media Statement
Friday, March 16, 2018]

WHO & Regional Offices [to 17 March 2018]

WHO & Regional Offices [to 17 March 2018]

Latest News
India takes on malaria in its highest burden state
14 March 2018 – India has made major inroads in reducing the toll of malaria. But the path towards elimination has proven a challenge in the eastern state of Odisha, which carries more than 40% of the country’s malaria burden. This photo story illustrates how in recent years, the state government has dramatically scaled up efforts to prevent, diagnose and treat malaria – with impressive results in a short span of time

Diphtheria vaccination campaign for 2.7 million children concludes in Yemen
March 2018 – WHO, UNICEF and national health authorities have completed a large-scale vaccination campaign to control the spread of diphtheria in Yemen. The campaign targeted nearly 2.7 million children aged 6 weeks to 15 years in 11 governorates.

Have your say and help give every child the best start in life
March 2018 – The Nurturing Care Framework for early childhood development is now entering its second phase of online consultations. The Framework builds on state-of-the-art evidence of effective interventions and recognises the critical importance of an enabling environment, with policies, information and services in a range of sectors including health, nutrition, education, social protection and child protection. The Framework will be launched at the time of the World Health Assembly in May 2018. The consultation runs until 28 March 2018.

Saving lives by sharing knowledge online
March 2018 – In June 2017, WHO publicly launched its own Massive Open Online Courses platform – OpenWHO – offering online courses specially tailored for health emergency responders.

Pacific leadership in new WHO global commission on noncommunicable diseases
March 2018 – Globally, communities are struggling to cope with the growing burden of noncommunicable diseases (NCDs), such as heart disease, stroke, diabetes, and cancers. In another step forward in combatting this epidemic, WHO has established an Independent Global High-level Commission on Noncommunicable Diseases, where the Tongan Minister of Health and Public Enterprises, Dr Saia Ma’u Piukala, has been appointed as one of the commissioners who will help raise awareness of the issues and experiences of NCDs in the Pacific.

Weekly Epidemiological Record, 16 March 2018, vol. 93, 11 (pp. 117–132)
:: Vaccine-derived polioviruses outbreaks and events in 3 provinces of Democratic Republic of the Congo, 2017
:: Emergence of monkeypox in West and Central Africa, 1970–2017

WHO Regional Offices
Selected Press Releases, Announcements
WHO African Region AFRO
Selected Featured News
:: On the frontlines of the fight against Lassa fever in Nigeria  16 March 2018
:: WHO establishes emergency water, sanitation and hygiene (WASH) services in health facilities to mitigate public health risks in South Sudan  16 March 2018
:: Polio personnel support Lassa fever response in Nigeria for rapid containment of an unprecedented outbreak.  15 March 2018
:: Kenya Certified Free of Guinea worm disease  14 March 2018
:: WHO to roll out integrated disease surveillance training in districts hosting refugees.
13 March 2018
:: WHO supports Nigeria to respond to new cholera outbreak in Borno State  13 March 2018
:: South Sudan declares Rift Valley fever outbreak in parts of Eastern Lakes State  12 March 2018

WHO Region of the Americas PAHO
:: PAHO urges countries to vaccinate against measles to maintain its elimination in the Americas (03/16/2018)
[See Milestones/Perspectives above for more detail]

WHO South-East Asia Region SEARO
:: Delhi TB Summit: WHO South-East Asia countries commit to intensified efforts, concrete progress to End TB 14 March 2018
[See Milestones/Perspectives above for more detail]
WHO European Region EURO
:: Seven years of grief: Syrian doctors and psychologists talk about the mental scars of war 16-03-2018
:: Out of conflict, a new life for Syrian health workers in Turkey 15-03-2018
:: Albania mounts rapid and comprehensive response to measles outbreak 14-03-2018
::  Meetings with high-level Finnish delegation focus on emergencies, communicable and noncommunicable diseases 13-03-2018

WHO Eastern Mediterranean Region EMRO
:: Seven years of Syria’s health tragedy   14 March 2018
:: WHO responds to humanitarian needs of people living with HIV in Benghazi  8 March 2018

WHO Western Pacific Region
:: Pacific leadership in new WHO global commission on noncommunicable diseases
SUVA, Fiji, 13 March 2018 – Globally communities are struggling to cope with the growing burden of noncommunicable diseases (NCDs), such as heart disease, stroke, diabetes, and cancers. In another step forward in combatting this epidemic, WHO has established an Independent Global High-level Commission on Noncommunicable Diseases, where the Tongan Minister of Health and Public Enterprises, Dr Saia Ma’u Piukala, has been appointed as one of the commissioners who will help raise awareness of the issues and experiences of NCDs in the Pacific.
:: Emergency health team deployed to earthquake-affected provinces of Papua New Guinea
08 March 2018.

CDC/ACIP [to 17 March 2018]

CDC/ACIP [to 17 March 2018]

Latest News
CDC Warns Of Deadly Outbreak of Yellow Fever in Brazil – Media Statement
Friday, March 16, 2018
In response to a large, ongoing outbreak of yellow fever in multiple states of Brazil, including near large urban areas and popular tourist destinations, CDC is recommending travelers to the country protect themselves from yellow fever by getting the yellow fever vaccine at least 10 days before travel, and taking steps to prevent mosquito bites during their travel.
CDC recommends that people who are unable to get yellow fever vaccine or aren’t recommended to get it should avoid traveling to areas of Brazil where yellow fever vaccination is recommended. Travelers going to areas with ongoing outbreaks may consider getting a booster dose of yellow fever vaccine if it has been 10 or more years since they were vaccinated…

MMWR News Synopsis for MARCH 15, 2018
:: Vaccine-Derived Polioviruses – Three Provinces, Democratic Republic of the Congo, 2017
In 2017 (as of 8 March 2018) the Democratic Republic of Congo (DRC) reported 25 cases of vaccine-derived poliovirus (VDPV). DRC health officials and Global Polio Eradication Initiative (GPEI) partners are collaborating to strengthen population immunity and surveillance with the goal of interrupting virus transmission. The last confirmed wild poliovirus case in the DRC occurred in December 2011; however, the country continues to report cases of vaccine-derived polioviruses (VDPVs). VDPVs can emerge from oral poliovirus vaccine (OPV) and spread within populations with low immunity to the virus. In 2017 (as of 8 March 2018), 25 cases of VDPV were reported in three provinces. In response to these cases, supplementary immunization activities were conducted June – December 2017.  Because of limitations in surveillance and poor immunization activities, VDPV circulation will likely continue in 2018, requiring additional immunization programs. DRC health officials and Global Polio Eradication Initiative (GPEI) partners are increasing human and financial resources to improve all aspects of the response.

Emergence of Monkeypox – West and Central Africa, 1970-2017
Monkeypox has re-emerged in Africa during the past decade, leading to more reports of human monkeypox cases in people. Many of these cases have been reported in countries that have not reported monkeypox in 40 years. During the past decade, cases of human monkeypox have been reported from more countries than in the previous 40 years. Since 2016, confirmed cases have occurred in Central African Republic, the Democratic Republic of the Congo, Liberia, Nigeria, Republic of Congo, and Sierra Leone; and captive chimpanzees were infected in Cameroon. Monkeypox causes significant illness and death in people and other animals; no specific treatment exists. The World Health Organization and CDC are developing updated guidance and regional trainings to improve capacity for laboratory-based surveillance, detection, and prevention of monkeypox as well as improved patient care and outbreak response.


ECDC – European Centre for Disease Prevention and Control  [to 17 March 2018]

ECDC – European Centre for Disease Prevention and Control  [to 17 March 2018]

16 March 2018
Rapid risk assessment: Outbreak of yellow fever in Brazil, Third update.
In September 2017, the Ministry of Health in Brazil declared the end of the 2016–2017 yellow fever outbreak in the country. The upsurge of human cases since December 2017 and the continuous non-human primate epizootics since September 2017 indicate a continued or resumed increase in yellow fever virus circulation in Brazil. Since January 2018, most of the yellow fever cases have been reported from São Paulo, Rio de Janeiro and Minas Gerais states.

16 March 2018
Communicable disease threats report, 11 – 17 March 2018, Week 11
The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue covers the period 11-17 March 2018 and includes updates on seasonal influenza, dengue, measles, Borna diseas virus, hepatitis A, Lassa fever, yellow fever and malaria.
PDF: Communicable Disease Threats Report, 17 March 2018



EDCTP    [to 17 March 2018]
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
Latest news
15 March 2018
EDCTP contribution to epidemic preparedness: consortia ALERRT and PANDORA-ID-NET
At the 1st International Conference on (Re-)Emerging Infectious Diseases(ICREID) which took place in Addis Ababa on 12-14 March 2018, a symposium was dedicated to two EDCTP-funded epidemic research preparedness consortia: the African coaLition for Epidemic Research, Response and Training (ALERRT), and the Pan-African Network for Rapid Research, Response, Relief and Preparedness for Infectious Diseases Epidemics (PANDORA-ID-NET).

European Medicines Agency  [to 17 March 2018]
EMA Management Board: highlights of March 2018 meeting
Board adopts 2017 report on veterinary medicines for minor use minor species and hears update on clinical trial portal and database
…Review of clinical trial portal and database
The Board received an update on progress with the development of the European Union (EU) portal and database. Based on the experience with this complex development so far, the developer has submitted a revised project plan with improved project management, development and testing processes and resources. It also contains increased contingency…
Advanced therapies: achievements and challenges
Dr Martina Schüssler-Lenz, chair of EMA’s Committee for Advanced Therapies (CAT), also deputy head of advanced therapy medicinal products at the Paul-Ehrlich Institute (PEI) in Germany, presented the achievements and ongoing challenges in the area of advanced therapies, i.e. medicines that are based either on cells, genes or tissues. These medicines offer new treatment options for rare diseases and patients with high unmet medical need.
Ten advanced therapies have been granted an EU-wide marketing authorisation since the creation of the CAT in 2009. Four advanced therapies are currently under evaluation, including one cell-based and three gene-based therapies. In 2018, the CAT expects to start evaluating four additional medicines.
“We are observing rapidly evolving scientific and technical innovation entering the field of advanced therapies,” explained Dr Schüssler-Lenz, “but the Committee is well set up to cope with the scientific and regulatory challenges ahead due to its expertise and the way members interact and learn from each other.”
Dr Schüssler-Lenz also noted that requests for scientific advice for advanced therapies have increased significantly between 2012 and 2017 and that the CAT is now routinely involved in all scientific advice procedures for these medicines.
FDA [to 17 March 2018]
What’s New for Biologics
March 14, 2018 Approval Letter – Trumenba (PDF – 96KB)
Posted: 3/15/2018
Fondation Merieux  [to 17 March 2018]
March 14, 2018  Bamako, Mali
A new mobile laboratrory to combat epidemics more efficiently I the G5 Sahel
A second mobile laboratory was inaugurated on March 1, 2018 at the Charles Mérieux Center for Infectious Disease. It joins a first mobile laboratory that was provided to Malian authorities in 2014. It will benefit all G5 Sahel member countries: Burkina Faso, Chad, Mali, Mauritania and Niger. The lab will enable health professionals in these countries to rapidly diagnose outbreaks of highly pathogenic diseases with potentially serious consequences for the health and safety of the local communities.
JEE Alliance  [to 17 March 2018]
Meeting of the Alliance Advisory Group on 27 February 2018
On 27 February, the Advisory Group of the Alliance met at the OIE Headquarters in Paris. The aim of the meeting was to discuss the role of the Alliance in the changing health security landscape, the strategic targets for health security capacity building, and the programme and working methods in 2018…

NIH  [to 17 March 2018]
March 15, 2018
H7N9 influenza vaccine clinical trials begin
Two new clinical trials testing an experimental vaccine to prevent influenza caused by an H7N9 influenza virus are now enrolling volunteers at sites across the United States. The Phase 2 studies, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), will test different dosages of the inactivated influenza vaccine candidate (called 2017 H7N9 IIV) as well as different vaccination schedules. The studies also will evaluate whether an adjuvant boosts the immune responses of people receiving the vaccine…

NIDA’s 2018 Avant-Garde awards highlight immune response and killer cells
March 13, 2018 — NIH’s awards support groundbreaking approaches to HIV prevention and treatment.
With diverse proposals focused on everything from natural killer cells to therapeutic vaccines to treat HIV, three recipients have been selected for the 2018 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. The awards will each provide $500,000 per year for up to five years (subject to the availability of funds) to support the research of three scientists, Drs. Catherine Blish, Nathaniel Landau, and Sara Sawyer. NIDA’s annual Avant-Garde Award competition, now in its 11th year, is intended to stimulate high-impact research that may lead to groundbreaking opportunities for the prevention and treatment of HIV/AIDS in drug users…

 NIH scientists describe potential antibody approach for treating multidrug-resistant Klebsiella pneumoniae
March 13, 2018 — Promising concept may lead to an alternative to antibiotics.

NIH experts call for transformative research approach to end tuberculosis
March 9, 2018 — A more intensive biomedical research approach is necessary to control and ultimately eliminate tuberculosis (TB), according to a perspective published in the March 2018 issue of The American Journal of Tropical Medicine and Hygiene. In the article, authors Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and Robert W. Eisinger, Ph.D., special assistant for scientific projects at NIAID, discuss the need to modernize TB research by applying new diagnostic, therapeutic, and vaccine approaches. The perspective is based on a lecture delivered by Dr. Fauci on Nov. 17, 2017 in Moscow at the first World Health Organization Global Ministerial Conference, “Ending TB in the Sustainable Development Era: A Multisectoral Response.”…

UNAIDS [to 17 March 2018]
14 March 2018
Feature story
Improving data on key populations
14 March 2018
UNAIDS has relaunched its Key Populations Atlas. The online tool that provides a range of information about members of key populations worldwide—sex workers, gay men and other men who have sex with men, people who inject drugs, transgender people and prisoners—now includes new and updated information in a number of areas. And in addition to data on the five key populations, there are now data on people living with HIV.
Chief among the new data is information on punitive laws, such as denial of the registration of nongovernmental organizations, and on laws that recognize the rights of transgender people. The overhaul of the site was undertaken in consultation with representatives of civil society organizations, including the International Lesbian, Gay, Bisexual, Trans and Intersex Association, which supplied some of the new data on punitive laws…

UNICEF  [to 17 March 2018]
Selected Press Releaases
Geneva Palais briefing note on UNICEF Rohingya Joint Response Plan
GENEVA, 16 March 2018 – This is a summary of what was said by Marixie Mercado, UNICEF spokesperson in Geneva – to whom quoted text may be attributed – at today’s press briefing at the Palais des Nations in Geneva.

Briefing note on the situation of children in Afrin and Eastern Ghouta, Syria
GENEVA, 16 March 2018 – This is a summary of what was said by Marixie Mercado, UNICEF spokesperson in Geneva – to whom quoted text may be attributed – at today’s press briefing at the Palais des Nations in Geneva.

No end in sight to seven years of war in Syria: children with disabilities at risk of exclusion
BEIRUT/AMMAN/DAMASCUS, 12 March 2018 – With no end in sight to the war in Syria, children with disabilities risk being excluded and forgotten.

Wellcome Trust  [to 17 March 2018]
News / Published: 13 March 2018
Wellcome’s goals: support global research to tackle global challenges
News / Published: 13 March 2018
Cell and developmental biology
Genetics, genomics and molecular biology
Infectious disease and the immune system
Influencing policy
Population health
In March 2017, Wellcome announced five ambitious goals to support research globally. Today we look at what we have achieved so far and what we are working towards in 2018.
Throughout 2017 we have worked towards these goals by working with colleagues from across the world.
Collaboration brings fresh ideas and new perspectives. Bringing people together from diverse backgrounds, often across borders, leads to new ways of thinking, better solutions and faster progress.
In 2016/17, Wellcome made 939 awards worth £1.1 billion, more than ever before and double what we supported a decade ago. We currently fund research activity in more than 100 countries and our non-UK funding continues to increase, largely driven by our commitment to major initiatives such as CEPI (opens in a new tab), CARB-X (opens in a new tab), GARD-P (opens in a new tab), DELTAS and H3Africa (opens in a new tab), and by increased investments in our Africa and Asia Programmes
News / Published: 9 March 2018
Sir Damon Buffini to stand down from our Board of Governors
News / Published: 13 March 2018
After six years as a Wellcome Governor, Sir Damon Buffini will step down later this year.
Sir Damon joined Wellcome in September 2012. He was awarded a knighthood in the Queen’s Birthday Honours 2016 for voluntary and charitable services.
He is a founding partner of Permira, a private equity firm with global reach. He was managing partner from 1997 to 2007 and Chair from 2007 to 2010…

BIO    [to 17 March 2018]
Mar 12 2018
International Council of Biotech Associations Launches New Website
Washington, D.C. (March 12, 2018) – The International Council of Biotech Associations (ICBA) today announced the launch of internationalbiotech.org, a new website to support the organization’s mission of growing and connecting the innovative biotechnology industry worldwide.
The website unites publicly available resources of ICBA members, providing a virtual library of materials ranging from economic and employment data to issue specific whitepapers. The site’s interactive map demonstrates the distribution of the biotechnology industry around the world, enabling users to easily contrast key economic data markers, including the percent of GDP spent by businesses and governments on research and development.
“The increasingly global biotechnology industry provides breakthrough products and technologies that combat debilitating and rare diseases, reduce our environmental footprint, feed the hungry, use less and cleaner energy, and have safer, cleaner and more efficient industrial manufacturing processes,” said Andrew Casey, Chair of the ICBA and President & CEO, BIOTECanada. “The challenges and opportunities faced by the biotechnology industry cross borders. This website demonstrates the steps our industry is taking to better coordinate, organize and face these issues around the world together.”

DCVMN – Developing Country Vaccine Manufacturers Network  [to 17 March 2018]
5 April 2018
Webinar: The new Future Vaccine Manufacturing Hub, collaborating with DCVMN
Prof Robin Shattock, Professor of Mucosal Infection and Immunity, Imperial College, London
Thursday, April 5, 2018 9:00 am
Europe Summer Time (Paris, GMT+02:00)

Journal Watch

Journal Watch

   Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focus on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.

If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org

The impact of a human papillomavirus (HPV) vaccination campaign on routine primary health service provision and health workers in Tanzania: a controlled before and after study

BMC Health Services Research
(Accessed 17 March 2018)

Research article
The impact of a human papillomavirus (HPV) vaccination campaign on routine primary health service provision and health workers in Tanzania: a controlled before and after study
The burden of cervical cancer and shortage of screening services in Tanzania confers an urgent need for human papillomavirus (HPV) vaccination. However, the sustainability and impact of another new vaccine cam…
Authors: Katherine E. Gallagher, Tusajigwe Erio, Kathy Baisley, Shelley Lees and Deborah Watson-Jones
Citation: BMC Health Services Research 2018 18:173
Published on: 12 March 2018