Lancet publishes retraction of Wakefield et al; Offit commentary

Lancet published a retraction of Wakefield AJ, Murch SH, Anthony A, et al. “Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.” Lancet 1998; 351: 637–41:

“Following the judgment of the UK General Medical Council’s Fitness to Practise Panel on Jan 28, 2010, it has become clear that several elements of the 1998 paper by Wakefield et al are incorrect, contrary to the findings of an earlier investigation.2 In particular, the claims in the original paper that children were “consecutively referred” and that investigations were “approved” by the local ethics committee have been proven to be false. Therefore we fully retract this paper from the published record.”
The Editors of The Lancet
Hodgson H. A statement by The Royal Free and University College Medical School and The Royal Free Hampstead NHS Trust. Lancet 2004; 363: 824.
http://download.thelancet.com/flatcontentassets/pdfs/S0140673610601754.pdf

The Philadelphia Inquirer carries an article by Dr. Paul A. Offit which comments on the retraction and the impact of the original Lancet article.  The MMR vaccine scare: How bad science resulted in suffering and death is available at: http://www.philly.com/inquirer/currents/84326297.html. Dr. Offit is chief of the division of infectious diseases at the Children’s Hospital of Philadelphia and provides oversight for the Center for Vaccine Ethics and Policy, which publishes this weekly update.

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