Science
14 May 2010  Vol 328, Issue 5980, Pages 777-936
http://www.sciencemag.org/current.dtl

Special Issue: Tuberculosis & Malaria

Landscapes of Infection
Stella Hurtley, Caroline Ash, and Leslie Roberts

Redrawing Africa’s Malaria Map
Martin Enserink
Smaller countries on the hardest-hit continent have shown how aggressive malaria control can slash cases and deaths. Can the big ones follow?

As Challenges Change, So Does Science
Martin Enserink
Although nobody believes that it is possible in the next 10, 20, or even 30 years, the call to eradicate malaria, combined with the plummeting disease burden, are already reshaping the scientific agenda. |

Malaria’s Drug Miracle in Danger
Martin Enserink
Like many others before it, the latest generation of malaria drugs is losing its punch. This time, can global disaster be averted?

If Artemisinin Drugs Fail, What’s Plan B?
Martin Enserink
If the current generation of artemisinin-based combination therapies should fail, does the world have a solid backup plan? The short answer: No.

The ‘Do Unto Others’ Malaria Vaccine
Gretchen Vogel
Once neglected, research on transmission-blocking vaccines for malaria is gaining new prominence.

Shrinking the Malaria Map From the Outside In
Leslie Roberts
A debate is brewing over how best to fight malaria: Go for the quick wins, or the worst places first, or both?

Elimination Meets Reality in Hispaniola
Leslie Roberts
Hispaniola’s fledging program to eliminate malaria, now sidetracked by the earthquake, illustrates the difficulties that arise when ambitious goals collide with reality.

Reviews
Tuberculosis: What We Don’t Know Can, and Does, Hurt Us
David G. Russell, Clifton E. Barry, 3rd, and JoAnne L. Flynn

The Population Dynamics and Control of Tuberculosis
Christopher Dye and Brian G. Williams

That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda
Stefan H. I. Kappe, Ashley M. Vaughan, Justin A. Boddey, and Alan F. Cowman

The Selection Landscape of Malaria Parasites
M. J. Mackinnon and K. Marsh