Vaccine
http://www.sciencedirect.com/science/journal/0264410X
Volume 28, Issue 38 pp. 6123-6402 (31 August 2010)

Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience Original Research Article
Pages 6210-6220
Beate Sander, Chris T. Bauch, David Fisman, Robert A. Fowler, Jeffrey C. Kwong, Andreas Maetzel, Allison McGeer, Janet Raboud, Damon C. Scales, Marija Zivkovic Gojovic, Murray Krahn

Abstract
In response to the pandemic H1N1 influenza 2009 outbreak, many jurisdictions undertook mass immunization programs that were among the largest in recent history. The objective of this study was to determine the cost-effectiveness of the mass H1N1 immunization program in Ontario, Canada’s most populous province (population 13,000,000). This analysis suggests that a mass immunization program as carried out in Ontario and many other high-income health care systems in response to H1N1 2009 was effective in preventing influenza cases and health care resource use and was also highly cost-effective despite the substantial program cost.