“Painful Failure of Promising Genital Herpes Vaccine”

Science
15 October 2010  Vol 330, Issue 6002, Pages 281-412
http://www.sciencemag.org/current.dtl

News of the Week
Immunology:
Painful Failure of Promising Genital Herpes Vaccine
Jon Cohen

A vaccine designed to ward off genital herpes has failed in a large clinical trial, abruptly ending the product’s seemingly promising future. After 8 years of study in more than 8000 women in the United States and Canada, there was not even a hint of a positive result against the sexually transmitted disease caused by herpes simplex virus-2.