The Lancet Infectious Disease
Nov 2010  Volume 10  Number 11  Pages 737 – 812
http://www.thelancet.com/journals/laninf/issue/current

Articles
Hepatitis B immune memory in children primed with hexavalent vaccines and given monovalent booster vaccines: an open-label, randomised, controlled, multicentre study
Alessandro Remo Zanetti, Luisa Romanò, Cristina Giambi, Anna Pavan, Vito Carnelli, Guglielmino Baitelli, Giancarlo Malchiodi, Edgardo Valerio, Antonella Barale, Maria Anna Marchisio, Domenico Montù, Alberto Eugenio Tozzi, Fortunato D’Ancona, for the study group

Preview
5 years after immunisation with hexavalent vaccines, immunological memory seems to persist in children with anti-HBs concentrations lower than 10 mIU/mL, suggesting that booster doses are not needed. Additional follow-up is needed.