The Lancet
Nov 13, 2010  Volume 376  Number 9753  Pages 1617 – 1710
http://www.thelancet.com/journals/lancet/issue/current

Comment
Poliomyelitis eradication: another step forward
Nigel W Crawford, Jim P Buttery

Preview
In The Lancet today, Roland Sutter and colleagues1 provide randomised data for a new combination bivalent type 1 and 3 oral poliovirus vaccine (bOPV) in India. This vaccine will be important for the poliomyelitis endgame, which formally began in 1988 when the World Health Assembly outlined plans for worldwide poliomyelitis eradication by 2000.2 With four endemic poliomyelitis countries remaining (India, Pakistan, Afghanistan, and Nigeria) and with intermittent epidemics worldwide, this goal remains elusive.