Vaccine
Volume 30, Issue 6 pp. 983-1234 (1 February 2012)
http://www.sciencedirect.com/science/journal/0264410X

The vaccine adverse event reporting system and vaccine safety research in the genomics era
Original Research Article
Pages 1162-1164
Robert Lowell Davis

Abstract
Advances in genetics hold promise for integrating genomics into vaccine safety research. Given the rarity of many vaccine adverse effects, and the challenges in finding sufficient numbers of patients to study, consideration should be given to employing the Vaccine Adverse Event Reporting System (VAERS) for genetic studies of vaccine adverse events. VAERS could be used to build a repository of biospecimens allowing for the systematic evaluation of vaccine adverse events. If successful, such research would enable the identification of specific subgroups of people at particularly increased risk for adverse events.