Science Translational Medicine
8 February 2012 vol 4, issue 120
http://stm.scienceag.org/content/mcurrent

Focus – Cancer
Improving Immunotherapy: Revisiting the Immunologist’s Little Secret
Jay A. Berzofsky
8 February 2012: 120fs4

Synergy between intracellular and extracellular sensing mechanisms of the innate immune system improves adaptive immune responses to cancer vaccines and clearance of tumors.