Tuberculosis Vaccines: A Strategic Blueprint for the Next Decade
Supplement to Tuberculosis Vol. 92/S1 (2012) S1–S35 ELSEVIER
http://www.tuberculosisjournal.com/supplements
Co-Editors: Michael J. Brennan and Jelle Thole

Contents

EDITORIALS
A New TB Vaccine Blueprint
P.J. Brennan S1
This special Supplement to Tuberculosis is distinguished by the presentation of the important document Tuberculosis Vaccines: A Strategic Blueprint for the Next Decade. This roadmap for the future of vaccine development against tuberculosis was preceded by the former Blueprint for Tuberculosis Vaccine Development arising from a workshop held in the Washington DC area under the chairmanship of Dr. Barry Bloom in 1998 and A Framework for the Development, Clinical Study and Introduction of Improved TB Vaccines for the Global Community, developed by the Global Forum on TB Vaccines Research and Development at WHO Headquarters, Geneva, June 2001 organized by Dr. Uli Fruth and Dr. Michael Brennan…
Transforming Biomedical Research to Develop Effective TB Vaccines: The Next Ten Years
C.F. Sizemore, A.S. Fauci S2
Planning in the Context of a Virtuous Cycle for Tuberculosis Vaccine Development
P.M. Small S4

THE TB VACCINE BLUEPRINT
Tuberculosis Vaccines: A Strategic Blueprint for the Next Decade
M.J. Brennan, J. Thole (Co-Editors) S6

OPINION PIECES: OPINIONS AND PERSPECTIVES ON THE TB VACCINE BLUEPRINT
Creativity in tuberculosis research and discovery
D. Young, F.A.W. Verreck S14
Ten challenges for TB biomarkers
T.H.M. Ottenhoff, J.J. Ellner, S.H.E. Kaufmann S17
Clinical trials of TB vaccines: Harmonization and cooperation
H. Mahomed, P.B. Fourie S21
Rational approach to selection and clinical development of TB vaccine candidates
L. Barker, L. Hessel, B. Walker S25
Bridging the gap: Engaging researchers and advocates to build support for TB vaccine research and development
M. Kennell, J. Woolley S30
The blueprint for vaccine research & development: Walking the path for better TB vaccines
C. Lienhardt, U. Fruth, M. Greco S33