The Lancet  
Jun 30, 2012  Volume 379  Number 9835  p2401 – 2500
http://www.thelancet.com/journals/lancet/issue/current

Perspective
The Lancet’s support for clinical trials in children and young people
Dougal S Hargreaves

Preview
In March, 2012, the European Medicines Agency (EMA) issued a call for more clinical trials to be done in children. Despite 5 years of European Union incentives to increase paediatric research, the EMA estimates that only 12% of clinical trials involve children.1 As a result, many medicines are still prescribed to children off licence.