Opinion: Towards an HIV cure: a global scientific strategy

Nature Reviews Immunology
August 2012 Vol 12 No 8
http://www.nature.com/nri/journal/v12/n7/index.html

Opinion: Towards an HIV cure: a global scientific strategy
Steven G. Deeks1, Brigitte Autran, Ben Berkhout, Monsef Benkirane, Scott Cairns, Nicolas Chomont, Tae-Wook Chun, Melissa Churchill, Michele Di Mascio, Christine Katlama, Alain Lafeuillade, Alan Landay, Michael Lederman, Sharon R. Lewin, Frank Maldarelli, David Margolis, Martin Markowitz, Javier Martinez-Picado, James I. Mullins, John Mellors, Santiago Moreno, Una O’Doherty, Sarah Palmer, Marie-Capucine Penicaud, Matija Peterlin, Guido Poli, Jean-Pierre Routy, Christine Rouzioux, Guido Silvestri, Mario Stevenson, Amalio Telenti, Carine Van Lint, Eric Verdin, Ann Woolfrey, John Zaia & Françoise Barré-Sinoussi for The International AIDS Society Scientific Working Group on HIV Cure2

Abstract
Given the limitations of antiretroviral therapy and recent advances in our understanding of HIV persistence during effective treatment, there is a growing recognition that a cure for HIV infection is both needed and feasible. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. Several priorities for basic, translational and clinical research were identified. This Opinion article summarizes the group’s recommended key goals for the international community.