Book: Genome-Based Therapeutics: Targeted Drug Discovery and Development: Workshop Summary
Authors:
Adam C. Berger and Steve Olson, Rapporteurs; Roundtable on Translating Genomic-Based Research for Health; Board on Health Sciences Policy; Institute of Medicine
IOM
September 5, 2012
http://iom.edu/Reports/2012/Genome-Based-Therapeutics-Targeted-Drug-Discovery-and-Development.aspx?utm_medium=etmail&utm_source=Institute%20of%20Medicine&utm_campaign=09.05.12+Report+-+Genomics+Therapeutics&utm_content=New%20Reports&utm_term=Academic

Description
Genome-Based Therapeutics summarizes a workshop that was held on March 21, 2012, titled New Paradigms in Drug Discovery: How Genomic Data Are Being Used to Revolutionize the Drug Discovery and Development Process. At this workshop the goal was to examine the general approaches being used to apply successes achieved so far, and the challenges ahead.

Genome-Based Therapeutics explains that new technologies have the potential to open up avenues of development and to identify new drug targets to pursue. Specifically, improved validation of gene-disease associations through genomics research has the potential to revolutionize drug production and lower development costs. Genetic information has helped developers by increasing their understanding of the mechanisms of disease as well as individual patients’ reactions to their medications. There is a need to identify the success factors for the various models that are being developed, whether they are industry-led, academia-led, or collaborations between the two.