Bulletin of the World Health Organization
Volume 90, Number 12, December 2012, 869-944
http://www.who.int/bulletin/volumes/90/12/en/index.html

PERSPECTIVES
Cost–effectiveness analysis of pandemic influenza preparedness: what’s missing?
Tom L Drake, Zaid Chalabi & Richard Coker
doi: 10.2471/BLT.12.109025
Article [HTML]

Conclusion
The evidence base for the cost–effectiveness of pandemic influenza preparedness policy options is small but growing rapidly. Modelling methods vary considerably between studies and the literature is limited in scope. To contribute to improving quality and consistency in this emerging study area, we recommend: (i) greater focus on low-resource settings; (ii) inclusion of non-pharmaceutical interventions; (iii) incorporation of health system capacity; and (iv) more robust analysis and presentation of pandemic event uncertainty. So, what’s missing from pandemic influenza preparedness cost–effectiveness analysis? Answer: poor countries, non-pharmaceutical interventions, health system capacity and pandemic uncertainty.