WHO: Human infection with influenza A(H7N9) virus
WHO enhanced its reporting on A(H7N9) and issued a risk assessment and other information as below:
WHO Risk Assessment as of 13 April 2013 [pdf, 122kb]
Excerpt
…Risk assessment
This initial risk assessment, which has been prepared in accordance with WHO’s published recommendations for rapid risk assessment of acute public health events 1 will be updated as further information becomes available.
– What is the risk of the occurrence of further cases in the affected areas of China and other areas?
The epidemiology of this virus among animals, including the main reservoirs of infection among animals and the extent of geographic spread, is not yet established. However, it is likely that most human H7N9 infections so far are associated with infection among as – of yet undetermined animals and that further human cases of infection should be expected.
– What is the risk of human-to-human transmission?
There is no evidence of sustained human-to-human transmission. However the two possible family clusters suggest that limited human-to-human transmission may occur where there is close contact between cases and other individuals, as occurs in families and, potentially, healthcare settings. Moreover, the genetic changes seen among these viruses suggesting adaptation to mammals is of concern, and further adaptation may occur.
– What is the risk of international spread?
At this time, there is no information to indicate international spread of this virus. However, it is possible that an infected person, who may or may not have symptoms, could travel to another country. However, if the virus cannot sustain human-to-human transmission, as appears to be the current situation, then extensive community spread is unlikely.
WHO does not advise special screening at points of entry with regard to this event, nor does it recommend that any travel or trade restrictions be applied.
Access the weekly report on number of confirmed human cases for influenza A(H7N9) reported to WHO
Data in WHO/HQ as of 10 April 2013, 14:22 GMT+1
Report will be updated once a week
WHO: Global Alert and Response (GAR) – Disease Outbreak News
http://www.who.int/csr/don/2013_03_12/en/index.html
Human infection with influenza A(H7N9) virus in China – update as of 12 April 2013
As of 12 April 2013 (17:30 CET), the National Health and Family Planning Commission notified WHO of an additional five laboratory-confirmed cases of human infection with influenza A(H7N9) virus. Of the latest laboratory-confirmed cases, three are from Zhejiang and two from Shanghai.
The first patient is a 66-year-old man from Zhejiang who became ill on 8 April 2013, the second patient is a 74-year-old man from Zhejiang who became ill on 13 April 2013, the third patient is a 54-year-old woman from Zhejiang who became ill on 13 April 2013, the fourth patient is a 53-year-old man from Shanghai who became ill on 3 April 2013, and the fifth patient is an 86-year-old man from Shanghai who became ill on 3 April 2013.
In addition, a patient earlier reported from Shanghai has died. To date, a total of 43 patients have been laboratory confirmed with influenza A(H7N9) virus in China; including 11 deaths. More than a thousand close contacts of the confirmed cases are being closely monitored.
The Chinese government is actively investigating this event and has heightened disease surveillance. Retrospective testing of recently reported cases with severe respiratory infection may uncover additional cases that were previously unrecognized. An inter-government task force has been formally established, with the National Health and Family Planning Commission leading the coordination along with the Ministry of Agriculture and other key ministries. The animal health sector has intensified investigations into the possible sources and reservoirs of the virus.
WHO is in contact with national authorities and is following the event closely. The WHO-coordinated international response is also focusing on work with WHO Collaborating Centres for Reference and Research on Influenza and other partners to ensure that information is available and that materials are developed for diagnosis and treatment and vaccine development. No vaccine is currently available for this subtype of the influenza virus. Preliminary test results provided by the WHO Collaborating Centre in China suggest that the virus is susceptible to the neuraminidase inhibitors (oseltamivir and zanamivir).
At this time there is no evidence of ongoing human-to-human transmission.
WHO does not advise special screening at points of entry with regard to this event, nor does it recommend that any travel or trade restrictions be applied.
http://www.who.int/csr/don/2013_04_12/en/index.html