New England Journal of Medicine
February 6, 2014  Vol. 370 No. 6
http://www.nejm.org/toc/nejm/medical-journal

Perspective
Ending AIDS — Is an HIV Vaccine Necessary?
Anthony S. Fauci, M.D., and Hilary D. Marston, M.D., M.P.H.
N Engl J Med 2014; 370:495-498February 6, 2014DOI: 10.1056/NEJMp1313771
The numbers of AIDS-related deaths and new HIV infections have decreased dramatically, thanks to prevention and treatment tools. But to control the pandemic more quickly and sustain the success, a safe and at least moderately effective vaccine is essential.