The Lancet
Mar 29, 2014 Volume 383 Number 9923 p1099 – 1182 e15
http://www.thelancet.com/journals/lancet/issue/current
Comment
Group B meningococcal vaccine: recommendations for UK use
Andrew J Pollard, Andrew Riordan, Mary Ramsay
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In the past two decades, meningitis and septicaemia caused by capsular group B Neisseria meningitidis have been responsible for more deaths and severe sequelae among previously healthy young children in the UK than any other infectious disease. The disease poses a particular challenge for frontline medical staff because it is rare (there are about 600–1400 cases per year in England and Wales1) and the early stages of the disease are indistinguishable from the large number of cases of minor viral infections that present to primary care and emergency services.