Clinical Infectious Diseases (CID)
Volume 58 Issue 10 May 15, 2014
http://cid.oxfordjournals.org/content/current

Modeling the effect of different vaccine effectiveness estimates on the number of vaccine prevented influenza associated hospitalizations in older adults
Alicia M. Fry1, Inkyu K. Kim1,2, Carrie Reed1, Mark Thompson1, Sandra S. Chaves1, Lyn Finelli1, and Joseph Bresee1
Author Affiliations
1Influenza Division, CDC, Atlanta, GA
2Battelle Memorial Institute, Atlanta, GA
Abstract
We compared influenza vaccine-prevented hospitalizations in adults aged>65 years for a range of hypothetical effectiveness estimates. During 2012-13, a vaccine with 10% effectiveness (66% coverage) would have averted ∼13,000 hospitalizations and a vaccine with 40% effectiveness would have averted ∼60,000 hospitalizations. Annual vaccination is merited in this vulnerable population.