PLoS Neglected Tropical Diseases (Accessed 23 August 2014)

PLoS Neglected Tropical Diseases
(Accessed 23 August 2014)
http://www.plosntds.org/

Vaccine Strategies for the Control and Prevention of Japanese Encephalitis in Mainland China, 1951–2011
Xiaoyan Gao, Xiaolong Li, Minghua Li, Shihong Fu, Huanyu Wang, Zhi Lu, Yuxi Cao, Ying He, Wuyang Zhu, Tingting Zhang, Ernest A. Gould, Guodong Liang Review | published 14 Aug 2014 | PLOS Neglected Tropical Diseases 10.1371/journal.pntd.0003015

Editorial
Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy
Daniel G. Bausch mail, Lara Schwarz
Published: July 31, 2014
DOI: 10.1371/journal.pntd.0003056
Initial text
Ebola virus is back, this time in West Africa, with over 350 cases and a 69% case fatality ratio at the time of this writing [1]. The culprit is the Zaire ebolavirus species, the most lethal Ebola virus known, with case fatality ratios up to 90%. The epicenter and site of first introduction is the region of Guéckédou in Guinea’s remote southeastern forest region, spilling over into various other regions of Guinea as well as to neighboring Liberia and Sierra Leone (Figure 1). News of this outbreak engenders three basic questions: (1) What in the world is Zaire ebolavirus doing in West Africa, far from its usual haunts in Central Africa? (2) Why Guinea, where no Ebola virus has ever been seen before? (3) Why now? We’ll have to wait for the outbreak to conclude and more data analysis to occur to answer these questions in detail, and even then we may never know, but some educated speculation may be illustrative…