Vaccine
Volume 32, Issue 44, Pages 5769-5888 (7 October 2014)
http://www.sciencedirect.com/science/journal/0264410X/32/44
Comparing the cost-effectiveness of two- and three-dose schedules of human papillomavirus vaccination: A transmission-dynamic modelling study
Original Research Article
Pages 5845-5853
Jean-François Laprise, Mélanie Drolet, Marie-Claude Boily, Mark Jit, Chantal Sauvageau, Eduardo L. Franco, Philippe Lemieux-Mellouki, Talía Malagón, Marc Brisson
Highlights
:: 2-dose girls-only HPV vaccination is likely to be cost-effective if protection is at least 10 years.
:: A 3rd dose is unlikely to be cost-effective if 2-dose duration of protection is longer than 30 years.
:: Vaccinating boys is unlikely to be cost-effective unless the cost/dose is substantially reduced.