Clinical Infectious Diseases (CID)
Volume 59 Issue 8 October 15, 2014
http://cid.oxfordjournals.org/content/current

Editorial Commentary: Treatment for Multidrug-Resistant Tuberculosis: It’s Worse Than We Thought!
Charles L. Daley and C. Robert Horsburgh, Jr
Clin Infect Dis. (2014) 59 (8): 1064-1065 doi:10.1093/cid/ciu578

Impact of 13-Valent Pneumococcal Conjugate Vaccination in Invasive Pneumococcal Disease Incidence and Mortality
Zitta Barrella Harboe, Tine Dalby, Daniel M. Weinberger, Thomas Benfield, Kåre Mølbak, Hans Christian Slotved, Camilla H. Suppli, Helle Bossen Konradsen, and Palle Valentiner-Branth
Clin Infect Dis. (2014) 59 (8): 1066-1073 doi:10.1093/cid/ciu524
Abstract
Introduction of PCV13-valent pneumococcal conjugate vaccine in the Danish childhood immunization program has led to further reduction in the incidence of invasive pneumococcal disease shortly after the vaccine’s introduction. A substantial population-level decline in pneumococcal-related mortality of nearly 30% among nonvaccinated persons was also observed.

Transforming the Fight Against Tuberculosis: Targeting Catalysts of Transmission
David W. Dowdy, Andrew S. Azman, Emily A. Kendall, and Barun Mathema
Clin Infect Dis. (2014) 59 (8): 1123-1129 doi:10.1093/cid/ciu506
Abstract
Transmission of tuberculosis in communities is driven by heterogeneities in human behavior, mycobacterial activity, and host susceptibility. The only realistic way to achieve ambitious targets for tuberculosis elimination is to tailor local interventions to these catalysts of tuberculosis transmission.