Clinical Infectious Diseases (CID)
Volume 60 Issue 4 February 15, 2015
http://cid.oxfordjournals.org/content/current
Editor’s choice: Durability of Antibody Response Against Hepatitis B Virus in Healthcare Workers Vaccinated as Adults
Naveen Gara, Adil Abdalla, Elenita Rivera, Xiongce Zhao, Jens M. Werner, T. Jake Liang, Jay H. Hoofnagle, Barbara Rehermann, and Marc G. Ghany
Clin Infect Dis. (2015) 60 (4): 505-513 doi:10.1093/cid/ciu867
Protective antibody levels persist long-term in a majority of healthcare workers after initial immunization. Those without protective levels have a rapid and robust response to a booster vaccine, suggesting that immunologic memory is long-lasting and booster vaccination is probably unnecessary.
Hepatitis A and B Immunity and Vaccination in Chronic Hepatitis B and C Patients in a Large United States Cohort
Emily Henkle, Mei Lu, Lora B. Rupp, Joseph A. Boscarino, Vinutha Vijayadeva, Mark A. Schmidt,
and Stuart C. Gordon for the Chronic Hepatitis Cohort Study (CHeCS) Investigators
Clin Infect Dis. (2015) 60 (4): 514-522 doi:10.1093/cid/ciu879
Abstract Full Text (HTML) Full Text (PDF)
Among Chronic Hepatitis Cohort Study patients, approximately 40% of chronic hepatitis B and C patients were potentially susceptible to hepatitis A or B. Clinicians should consider antibody testing and vaccination for this vulnerable population.