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Clinical and Translational Medicine
Published online: 14 February 2015
Vaccination in children with allergy to non active vaccine components
Fabrizio Franceschini1 , Paolo Bottau2 , Silvia Caimmi3 , Giuseppe Crisafulli4 , Liotti Lucia5 , Diego Peroni6 , Francesca Saretta7 , Mario Vernich8 , Carlotta Povesi Dascola9 and Carlo Caffarelli10
1. Pediatric Unit, “Ospedali Riuniti”, University Hospital, Ancona, Italy
2. Pediatric Unit, Imola Hospital, Imola, Italy
3. Pediatric Unit, Department of Pediatrics, University of Pavia, Pavia, Italy
4. Allergy Unit, Department of Pediatrics, University of Messina, Messina, Italy
5. Pediatric Unit, Civic Hospital, Senigallia, Italy
6. Clinica Pediatrica Unit, University of Ferrara, Ferrara, Italy
7. Pediatric Unit, Palmanova Hospital, Palmanova, Italy
8. Pediatric Unit, Bollate Hospital, Bollate, Italy
9. Clinica Pediatrica Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera-Universitaria, University of Parma, Parma, Italy
10. Clinica Pediatrica Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera-Universitaria, University of Parma, Via Gramsci 14, 43123 Parma, Italy
Abstract
Childhood immunisation is one of the greatest public health successes of the last century. Vaccines contain an active component (the antigen) which induces the immune response. They may also contain additional components such as preservatives, additives, adjuvants and traces of other substances. This review provides information about risks of hypersensitivity reactions to components of vaccines. Furthermore, recommendations to avoid or reduce reactions to vaccine components have been detailed.