Review Article – Chikungunya Virus and the Global Spread of a Mosquito-Borne Disease

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New England Journal of Medicine
March 26, 2015 Vol. 372 No. 13
http://www.nejm.org/toc/nejm/medical-journal

Review Article
Chikungunya Virus and the Global Spread of a Mosquito-Borne Disease
Scott C. Weaver, Ph.D., and Marc Lecuit, M.D., Ph.D.
N Engl J Med 2015; 372:1231-1239 March 26, 2015 DOI: 10.1056/NEJMra1406035
Chikungunya virus infection is a rapid-onset, febrile disease with intense asthenia, arthralgia, myalgia, headache, and rash. This mosquito-borne alphavirus has spread throughout the Caribbean and into much of Central America. Further spread in the Americas seems likely.