Vaccine
Volume 33, Issue 18, Pages 2097-2196 (27 April 2015)
http://www.sciencedirect.com/science/journal/0264410X/33/18

Influenza vaccination during pregnancy: A systematic review of fetal death, spontaneous abortion, and congenital malformation safety outcomes
Review Article
Pages 2108-2117
M. McMillan, K. Porritt, D. Kralik, L. Costi, H. Marshall
Highlights
– This article presents the findings of a systematic review that includes analysis of critical adverse events including congenital malformation, fetal death, and spontaneous abortion.
– It provides a detailed analysis of individual study characteristics and argues that meta-analysis for these outcomes may not be appropriate due to clinical and methodological heterogeneity.
– The systematic review investigates 1st trimester immunisation for congenital malformation outcomes, raising crucial design issues for future research studies.
– Results did not indicate that maternal influenza vaccination is associated with an increased risk of fetal death, spontaneous abortion, or congenital malformations.
– The review includes previously unpublished data and definitions from four studies and detailed vaccine composition where known

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Influenza and pertussis vaccination coverage in pregnant women
Original Research Article
Pages 2125-2131
Jolien Laenen, Mathieu Roelants, Roland Devlieger, Corinne Vandermeulen
Highlights
– 42.8% of pregnant women had immunization records for flu and 39.2% for pertussis, 23.6% had documentation for both vaccines.
– The coverage increases to 62% for influenza and 46% for pertussis when oral communication was considered in addition.
– Obstetricians and GP are most influential in decision of pregnant women to vaccinate.
– Women with a low education and those of foreign origin are more vulnerable for non-vaccination.