From Google Scholar+ [to 12 September 2015]

From Google Scholar & other sources: Selected Journal Articles, Newsletters, Dissertations, Theses, Commentary

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Parasitology
FirstView Article
Special Issue Research Article
Pertussis immunity and epidemiology: mode and duration of vaccine-induced immunity
F. M. G. MAGPANTAYa1, M. DOMENECH DE CELLÈSa1, P. ROHANIa1a2a3 and A. A. KINGa1a2a3a4 c1
a1 Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA
a2 Center for the Study of Complex Systems, University of Michigan, Ann Arbor, MI 48109, USA
a3 Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
a4 Department of Mathematics, University of Michigan, Ann Arbor, MI 48109, USA
SUMMARY
The resurgence of pertussis in some countries that maintain high vaccination coverage has drawn attention to gaps in our understanding of the epidemiological effects of pertussis vaccines. In particular, major questions surround the nature, degree and durability of vaccine protection. To address these questions, we used mechanistic transmission models to examine regional time series incidence data from Italy in the period immediately following the introduction of acellular pertussis (aP) vaccine. Our results concur with recent animal-challenge experiments wherein infections in aP-vaccinated individuals proved as transmissible as those in naive individuals but much less symptomatic. On the other hand, the data provide evidence for vaccine-driven reduction in susceptibility, which we quantify via a synthetic measure of vaccine impact. As to the precise nature of vaccine failure, the data do not allow us to distinguish between leakiness and waning of vaccine immunity, or some combination of these. Across the range of well-supported models, the nature and duration of vaccine protection, the age profile of incidence and the range of projected epidemiological futures differ substantially, underscoring the importance of the remaining unknowns. We identify key data gaps: sources of data that can supply the information needed to eliminate these remaining uncertainties.
Thesis
Factors Associated with Willingness to the Human Papillomavirus (HPV) Vaccine Adoption among Unmarried Women in Taiwan
TI Liu –
2015-07-23
Abstract
Cervical cancer is both the ten most common cause of cancer and the three most common cause of death from cancer in women. Cervical cancer is mainly caused by the virus called Human Papillomavirus (HPV). The virus spread through sexual contact. Treatment of cervical cancer not only affects the health of the patience herself but also put great financial and mental burden on the members in the family. The medical expenditure on cervical cancer is quite high. The early stage cervical cancer it is a high cure rate cancer. The main policy of government to prevent the cervical cancer now is by promoting female citizens to do Papanicolaou test (Pap smear) regularly and to take the HPV vaccine. However, Pap smear now is facing a difficulty to raise the screen rate, and Pap smear result sometimes has false result or human error in it and cause the delay of best treatment time. Therefore, prevention of Human Papillomavirus (HPV) by vaccine is far more important.

Considering the importance of taking HPV vaccine to prevent the cervical cancer, this study does sampling from the latest research: Family and Fertility (2008, 10th), Population of Health and Research Center, Health Promotion Administration, Ministry of Health and Welfare. This study use STATA to do the regression analysis by Probit model and Marginal effect. Dependent variables are the willingness of unmarried women to take the HPV vaccine and the willingness of married women to encourage the age 9-26 unmarried female family member to take HPV vaccine. Independent variables are social-economic status, health status, health behavior, health knowledge, and the frequency of using knowledge communication channels. The purpose of this study is to analysis the factors that influence the willingness of unmarried women to take HPV vaccine and also analysis the factors that influence the willingness of married women to encourage the age 9-26 unmarried female family member to take HPV vaccine.

The result of this study shows a high correlation: the willingness of unmarried women to take HPV vaccine is highly related to the education status of interviewee, the family’s economic status of interviewee, BMI of interviewee, and if the interviewee ever heard of Human Papillomavirus (HPV) vaccine. Furthermore, the factors that influence the willingness of married women to encourage the age 9-26 unmarried female family member to take HPV vaccine are closely related to the family’s economic status, the inhabited area of the married woman lived before 12 years old, the smoking habit of married woman, and if the married woman ever heard of Human Papillomavirus ( HPV). The empirical result of this study could be a reference for the government when drafting the health care and medical service strategy, and also this result could be a basis for promoting HPV vaccine by the department concerned.
Expert Review of Vaccines
Efficacy and effectiveness of live attenuated influenza vaccine in school-age children
Kathleen Coelingh*a, Ifedapo Rosemary Olajideb, Peter MacDonalda & Ram Yogevc
DOI:10.1586/14760584.2015.1078732
Published online: 07 Sep 2015
Abstract
Evidence of high efficacy of live attenuated influenza vaccine (LAIV) from randomized controlled trials is strong for children 2–6 years of age, but fewer data exist for older school-age children. We reviewed the published data on efficacy and effectiveness of LAIV in children ≥5 years. QUOSA (Elsevier database) was searched for articles published from January 1990 to June 2014 that included ‘FluMist’, ‘LAIV’, ‘CAIV’, ‘cold adapted influenza vaccine’, ‘live attenuated influenza vaccine’, ‘live attenuated cold adapted’ or ‘flu mist’. Studies evaluated included randomized controlled trials, effectiveness and indirect protection studies. This review demonstrates that LAIV has considerable efficacy and effectiveness in school-age children.