Clinical Therapeutics
November 2015 Volume 37, Issue 11, p2385-2608
http://www.clinicaltherapeutics.com/current

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Review of the Persistence of Herpes Zoster Vaccine Efficacy in Clinical Trials
Stephen J. Cook, Dennis K. Flaherty
p2388–2397
Published online: October 23 2015
Abstract
The live attenuated herpes zoster vaccine* was approved for the prevention of shingles in 2006. Initial Phase III clinical trials proved vaccine efficacy persisted during the study duration; however, assessment of long-term efficacy required additional studies. This article reviews efficacy data for the zoster vaccine that have been published since 2004. It focuses on studies assessing declining vaccine efficacy.

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Commentary
Personal Protective Equipment: Protecting Health Care Providers in an Ebola Outbreak
William A. Fischer II, David J. Weber, David A. Wohl
p2402–2410
Published online: October 6 2015
Preview
The recent Ebola epidemic that devastated West Africa has infected and killed more health care providers than any other outbreak in the history of this virus. An improved understanding of pathogen transmission and the institution of strategies to protect health care providers against infection are needed in infectious disease outbreaks. This review connects what is known about Ebola virus transmission with personal protective equipment (PPE) designed to arrest nosocomial transmission.