IVAC [International Vaccine Access Center] [to 12 March 2016]
http://www.jhsph.edu/research/centers-and-institutes/ivac/about-us/news.html

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White paper
Rotavirus: Common, Severe, Devastating, Preventable
ROTA Council
Posted on March 7, 2016
Overview
The ROTA Council white paper Rotavirus: Common, Severe, Devastating, Preventable is the most comprehensive and up-to-date source of information on rotavirus disease and vaccines.

The 50-page synthesis includes the latest evidence and programmatic information about:
:: Rotavirus disease, and why every child is vulnerable
:: Vaccines in global use, nationally available vaccines, and new vaccines on the horizon
WHO recommendations and key guidance on vaccine administration
:: Public health impact in high-income countries, middle-income countries, and low-income countries
:: Cost-effectiveness of rotavirus vaccines
:: Emerging data and areas for further research
:: 21 recommendations for stakeholders to scale up coverage of rotavirus vaccines to all children
Download the Executive Summary.
Download the full report: Rotavirus: Common, Severe, Devastating, Preventable

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[Undated]
Rwanda Study Demonstrates the Benefits of Routine Vaccination Against Rotavirus in Low-Income Settings
A new study published in February’s edition of the Lancet Global Health offers significant findings about the impact of pentavalent rotavirus vaccine on hospital admission for diarrhea and rotavirus in children in Rwanda, which in 2012 became the first low-income African country to introduce pentavalent rotavirus vaccine into its national immuniation program. Researchers from Rwanda’s Ministry of Health, CDC, WHO, and partner organizations examined trends in pediatric hospital admissions from 2009 to 2014 and looked at other epidemiological evidence from the country.

The study showed hospital admissions for acute gastroenteritis decreased by about half (48-49%) and admissions specific to rotavirus declined by 61-70% following introduction of rotavirus vaccine in the routine national immunization program. The greatest effect was recorded in children of vaccination age, but researchers noted a decrease in rotavirus diarrhea hospitalizations in almost every age group, suggesting herd immunity. Indirect protection of children too old to have been vaccinated has been previously reported in high-income and middle-income countries including the USA, Australia, and El Salvador, but this paper provides the first evidence of indirect protection from rotavirus vaccination in a high-burden, low-income setting.

This paper provides strong evidence of the public health impact of introducing rotavirus vaccine nationally in low-income settings, and the first data demonstrating the impact of routine pentavalent rotavirus vaccination in Africa. The reductions in hospital admissions for diarrhea noted in Rwanda is similar to decreases recorded after national rotavirus vaccine introductions in Brazil, Mexico, and Panama.