PLoS One [Accessed 9 April 2016]

Posted on by

PLoS One
http://www.plosone.org/
[Accessed 9 April 2016]

.
Research Article
Effectiveness of the 10-Valent Pneumococcal Conjugate Vaccine (PCV-10) in Children in Chile: A Nested Case-Control Study Using Nationwide Pneumonia Morbidity and Mortality Surveillance Data
Janepsy Diaz, Solana Terrazas, Ana L. Bierrenbach, Cristiana M. Toscano, Gizelton P. Alencar, Andrés Alvarez, Maria T. Valenzuela, Jon Andrus, Roberto del Aguila, Juan C. Hormazábal, Pamela Araya, Paola Pidal, Cuauhtemoc R. Matus, Lucia H. de Oliveira
Research Article | published 08 Apr 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0153141

.

Predicting and Evaluating the Epidemic Trend of Ebola Virus Disease in the 2014-2015 Outbreak and the Effects of Intervention Measures
Zuiyuan Guo, Dan Xiao, Dongli Li, Xiuhong Wang, Yayu Wang, Tiecheng Yan, Zhiqi Wang
Research Article | published 06 Apr 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0152438

.

Optimizing Real-Time Vaccine Allocation in a Stochastic SIR Model
Chantal Nguyen, Jean M. Carlson
Research Article | published 04 Apr 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0152950
Abstract
Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in delayed vaccine deployment, and the interaction between members of different cities facilitates a wide spatial spread of infection. Limited vaccine, time delays, and interaction (or coupling) of cities lead to tradeoffs that impact the overall magnitude of the epidemic. These tradeoffs mandate investigation of optimal strategies that minimize the severity of the epidemic by prioritizing allocation of vaccine to specific subpopulations. We use an SIR model to describe the disease dynamics of an epidemic which breaks out in one city and spreads to another. We solve a master equation to determine the resulting probability distribution of the final epidemic size. We then identify tradeoffs between vaccine, time delay, and coupling, and we determine the optimal vaccination protocols resulting from these tradeoffs.

.

A Performance Analysis of Public Expenditure on Maternal Health in Mexico
Edson Servan-Mori, Leticia Avila-Burgos, Gustavo Nigenda, Rafael Lozano
Research Article | published 04 Apr 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0152635