European Medicines Agency [to 23 April 2016]
http://www.ema.europa.eu/

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22/04/2016
First DNA vaccine in the EU recommended for use in salmon
Clynav to protect Atlantic salmon from serious infectious disease
The European Medicines Agency (EMA) has recommended granting a marketing authorisation in the European Union (EU) for Clynav, a DNA vaccine to protect Atlantic salmon against Salmon Pancreas Disease (SPD) caused by salmon alphavirus subtype 3.

SPD is a serious infectious disease which causes damage to the heart, pancreas and skeletal muscle and can lead to the death of salmon. The disease has become established in some Member States and outbreaks of SPD cause significant losses in salmon farms in the EU.

Clynav is the first DNA vaccine to be recommended for marketing authorisation in the EU. A DNA vaccine consists of a genetic sequence that triggers the production of proteins directly in the cells of the vaccinated animal. These proteins stimulate a protective immune response, in the case of Clynav against salmon alphavirus subtype 3, thereby preventing or reducing the impact of the disease should the fish subsequently be exposed to this virus…