Sabin Vaccine Institute [to 30 April 2016]
http://www.sabin.org/updates/ressreleases

.
April 28, 2016
Sabin PDP Begins Phase 1 Clinical Trial to Co-Administer Two Novel Hookworm Vaccine Candidates in Brazil
WASHINGTON, D.C. — April 29, 2016 — The Sabin Vaccine Institute (Sabin) today announced that its Product Development Partnership (Sabin PDP) began a Phase 1 clinical trial of Na-APR-1 (M74)/Alhydrogel® co-administered with Na-GST-1/Alhydrogel in Brazilian adults. The trial will evaluate the safety and immune response of co-administering these novel vaccine candidates in 60 healthy adults living in a hookworm-endemic area.

The George Washington University (GWU) in partnership with the Oswaldo Cruz Foundation (Fiocruz) of the Brazilian Ministry of Health is conducting the study in Americaninhas, Minas Gerais, Brazil. The study began in January and is expected to run through March 2017. Volunteers will be injected with one or both vaccine products, to determine if administering both at the same time produces an improved immune response over giving each of them separately.

“With this trial, we hope to build on the work of our previous studies in Brazil to develop a safe, effective and affordable vaccine to prevent human hookworm infection,” said David Diemert, MD, director of clinical trials of the Sabin PDP and associate professor at GWU in Washington, DC. “A vaccine, in combination with currently available drugs, could help turn the tide against this pervasive disease, which afflicts the world’s poorest communities.”…

.

Uganda Enacts Law to Improve National Immunization Efforts, Increase Domestic Financing for the National Program
KAMPALA, UGANDA — April 28, 2016 — The Sabin Vaccine Institute (Sabin) applauds the enactment of Uganda’s Immunization Act, 2016, which was recently signed into law by President Yoweri Museveni. The law mandates compulsory immunization of children, women of reproductive age and other target groups and establishes a new national immunization fund.

Notably, this legislation includes a provision to establish an “Immunization Financing and Administration Fund” to purchase vaccines and related supplies, cold chains and funding of immunization outreach activities. The fund will be financed through parliamentary appropriations and donations. The bill was introduced as a private members bill in the Ugandan Parliament in 2012 by Hon. Huda Oleru, a Member of Parliament from the Yumbe district, and was passed as an Act of parliament in December 2015…