Vaccine
Volume 34, Issue 27, Pages 3007-3220 (8 June 2016)
http://www.sciencedirect.com/science/journal/0264410X/34/27

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Cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women
Original Research Article
Pages 3149-3155
Jing Xu, Fangjun Zhou, Carrie Reed, Sandra S. Chaves, Mark Messonnier, Inkyu K. Kim
Abstract
Objective
To evaluate the cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women using data from three recent influenza seasons in the United States.
Design, setting, and participants
We developed a decision-analytic model following a cohort of 5.2 million pregnant women and their infants aged Main outcome measures
Total costs (direct and indirect), effects (QALY gains, averted case numbers), and incremental cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women (cost per QALY gained).
Results
Using a recent benchmark of 52.2% vaccination coverage among pregnant women, we studied a hypothetical cohort of 2,753,015 vaccinated pregnant women. With an estimated vaccine effectiveness of 73% among pregnant women and 63% among infants Conclusions
Influenza vaccination for pregnant women can reduce morbidity from influenza in both pregnant women and their infants aged