Africa CDC [to 06 Nov 2021] http://www.africacdc.org/ News Africa Centres for Disease Control and Prevention Designate Institut Pasteur Morocco and Rwanda Biomedical Centre COVID-19 Vaccination Centres of Excellence
2 November 2021
The Africa Centres for Disease Control and Prevention (Africa CDC), a Specialised Technical Institution of the African Union (AU), has designated two institutions to serve as part of a network of Centres of Excellence (CoE) for COVID-19 vaccination. These include the Institut Pasteur, Casablanca, Morocco and the Rwanda Biomedical Centre, Kigali. Africa has vaccinated only about 5% of its population with COVID-19 vaccine and a 70% coverage target has been set by the World Health Organisation to bring the pandemic under control.
Institut Pasteur of Morocco and Rwanda Biomedical Centre have both demonstrated efficiency in COVID-19 vaccination rollout in their respective countries. For instance, Morocco has vaccinated more than 80% of its targeted population. Rwanda has immunized about 25% of its eligible population and aims to achieve a 40% coverage by the end of 2021. The African CDC CoE for COVID-19 vaccination are expected to provide capacity building services to professionals from difference member states across Africa and share best practices on management of vaccination centres, logistics of vaccine distribution, and community engagement and risk communication.
“We are very excited that Morocco is part of this networks of Africa CDC CoE for COVID-19 vaccination and share Morocco’s experience and offer technical assistance if requested with other AU member states, says Professor Maaroufi Abderrahmane, Director of the Institut Pasteur of Morocco”
As part of the Africa CDC and Mastercard Foundation partnership on Saving Lives and Livelihood, 20 African Union member states representatives, implementing partners, and other international organsations will be meeting in Morocco in late November 2021 to share Morocco’s experiences. A similar exercise, with additional AU member states, will also be carried out at the Rwanda Biomedical Centre in early December…
National Health Commission of the People’s Republic of China [to 06 Nov 2021] http://en.nhc.gov.cn/ News Nov 6: Daily briefing on novel coronavirus cases in China
On Nov 5, 31 provincial-level regions and the Xinjiang Production and Construction Corps on the Chinese mainland reported 55 new cases of confirmed infections.
Targeted containment aims to curb COVID-19 while minimizing impact
Updated: 2021-11-04 | Xinhua — Local governments are leaving no stone unturned to curb infections while minimizing the impact on people’s lives and production. — Anti-epidemic measures such as mass nucleic acid testing, epidemiological investigations, origin tracing, targeted screening and quarantines, adjustment of medium and high-risk area classifications, have been immediately adopted to curb transmissions. — A slew of policies and measures have been rolled out to help mitigate the impact of local flare-ups since a COVID-19 outbreak over summer affected dozens of cities.
BEIJING — Shanghai Disneyland and Disneytown reopened Wednesday, just two days after a temporary closure for epidemic prevention and control works.
On the evening of Oct 31, Disneyland issued a statement saying entry has been suspended to cooperate with COVID-19 epidemiological investigation in other provinces and cities. The notice asked guests to undergo nucleic acid testing at the exit when leaving the resort.
“I spent a memorable Halloween at the resort along with tens of thousands of visitors,” said a visitor surnamed Li who celebrated her birthday at the park with her boyfriend. “Fireworks dazzled the sky as we completed our testing, while healthcare workers were busy conducting our tests effectively,” she recalled.
A total of 66,460 tests were conducted and all results came out negative as of 8 am Tuesday, in the two rounds of COVID-19 screening within 48 hours, including all cast members and third-party employees and tourists who had visited the facility during the weekend, according to a notice issued by Shanghai’s epidemic control headquarters on Tuesday.
The efficient response by Shanghai Disneyland resort mirrored the determined efforts across the country in the face of sporadic cluster infections. Meanwhile, local governments are leaving no stone unturned to curb infections while minimizing the impact on people’s lives and production…
Booster shots recommended
2021-11-04
China’s leading pulmonologists affirmed the effectiveness of COVID-19 vaccine booster shots and warned that elderly people should pay more attention to disease prevention, as many of them have not yet been vaccinated
Xi calls for enhancing vaccine accessibility, affordability in developing countries
2021-11-02
China is ready to work with all parties to enhance vaccine accessibility and affordability in developing countries and make positive contribution to building a global line of defense through vaccination, President Xi Jinping said on Saturday.
Xi calls for advancing mutual recognition of COVID-19 vaccines
2021-11-02
President Xi Jinping on Saturday called for equal treatment of different vaccines and advancing mutual recognition of vaccines in accordance with the World Health Organization’s Emergency Use Listing.
Organization Announcements Editor’s Note:
Careful readers will note that the number and range of organizations now monitored in our Announcements section below has grown as the impacts of the pandemic have spread across global economies, supply chains and programmatic activity of multilateral agencies and INGOs. Paul G. Allen Frontiers Group [to 06 Nov 2021] https://alleninstitute.org/news-press/ News Press Release Announcing the Allen Institute for Neural Dynamics, a new neuroscience division of the Allen Institute
November 4, 2021
New Institute will study how the brain’s circuitry and activity give rise to complex behavior, decision making and memory BARDA – U.S. Department of HHS [to 06 Nov 2021] https://www.phe.gov/about/barda/Pages/default.aspx News No new digest content identified. BMGF – Gates Foundation [to 06 Nov 2021] https://www.gatesfoundation.org/ideas/media-center Press Releases and Statements Bill & Melinda Gates Foundation Pledges $315 million to Support Innovations That Help Smallholder Farmers Adapt to Climate Threats Press release
Nov 02, 2021 Bill & Melinda Gates Medical Research Institute [to 06 Nov 2021] https://www.gatesmri.org/ The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people No new digest content identified. CARB-X [to 06 Nov 2021] https://carb-x.org/ News No new digest content identified. Center for Vaccine Ethics and Policy – GE2P2 Global Foundation [to 06 Nov 2021] https://centerforvaccineethicsandpolicy.net/ News/Analysis/Statements
:: Past weekly editions and posting of all segments of Vaccines and Global Health: The Week in Review are available here.
Q2 Solutions Beijing joins CEPI’s global network of COVID-19 vaccine testing labs
This network is the largest and only global group launched to harmonise the assessment of COVID-19 vaccines currently undergoing preclinical and clinical trials. Q2 Solutions laboratory in the US joined the network last year.
COVID-19
02 Nov 2021 DARPA – Defense Advanced Research Projects Agency [to 06 Nov 2021 https://www.darpa.mil/news News No new digest content identified. Duke Global Health Innovation Center[to 06 Nov 2021] https://dukeghic.org/ Our Blog No new digest content identified. EDCTP [to 06 Nov 2021] http://www.edctp.org/ The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials News
02 November 2021 EDCTP at COVID CIRCLE online event
02 November 2021 EDCTP Prizes 2020 awarded at the Tenth EDCTP Forum
EDCTP awarded its prizes for research excellence and the Pascoal Mocumbi Prize at the Tenth EDCTP Forum that was held from 17-21 October 2021 from Maputo, Mozambique & virtual.
From equity to priority setting: Where we can improve funding epidemic and pandemic research for the future
02/11/2021
A report, ‘Funding and undertaking research during the first year of the COVID-19 pandemic: COVID CIRCLE lessons for funders’, published today, presents key lessons and future guidance for research funders to address the challenges of funding and conducting research in the context of an epidemic or pandemic, particularly in low- and middle-income countries (LMICs).
Nearly two years into the COVID-19 pandemic, the global research community has begun to take stock of lessons learned when it comes to funding research during a global health crisis, especially in LMICs.
The report identified a number of barriers experienced by funders and researchers across the globe in the process of undertaking and funding COVID-19 research. These barriers include issues of equity and access, and delays to, and sometimes a lack of, regionally developed research priorities, hindering the alignment of funding and research.
Key lessons for funders from this pandemic that will enable future funding preparedness and response include:
the appreciation of the early development of the WHO & GloPID-R Research Roadmap;
leveraging pre-existing partnerships and funding to enable rapid response;
the need for greater support for open science and data sharing practices in epidemics, along with buy-in and support of LMICs;
the need for greater global funder collaboration.
Many examples of best research practice and innovative funding mechanisms that have taken place during the pandemic to date are featured. Such as the European and Developing Countries, Clinical Trial Partnership (EDCTP) rapid emergency funding mechanism which mobilised €12.75m for research implemented in 25 Sub-Saharan African countries. The report also provides specific recommendations on the actions that funders could pursue, particularly in low-resource settings.
Lessons learned in the report are framed around COVID CIRCLE’s ‘Funder principles for research in epidemics,Funders Principles for Supporting High-Quality Research for the Most Pressing Global Needs in Epidemics and Pandemics’ which build on best practice guidance from key stakeholders and include commitments to ensure that research outputs are shared rapidly to inform policy and practice in epidemic situations. These have been embedded into funding practices e.g. the Global Effort on COVID-19 Health Research (GECO) included adherence to the principles in its funding call guidelines.
The challenges and potential solutions for achieving the Funder Principles require action from a range of stakeholders. The authors of the report issue an urgent call for the Principles to be endorsed by research funders: they call upon donors, governments and any other entities supporting research to address needs during the current as well as future epidemics and pandemics…
International Coalition of Medicines Regulatory Authorities [ICMRA] http://www.icmra.info/drupal/en/news Selected Statements, Press Releases, Research No new digest content identified. ICRC [to 06 Nov 2021] https://www.icrc.org/en/whats-new Selected News Releases, Statements, Reports Reducing Civilian Harm in Urban Warfare: A Commander’s Handbook
We know that urban warfare kills, injures and displaces significantly more civilians – and destroys more critical civilian infrastructure and essential services – than any other combat in open areas.
05-11-2021 | Article
Haiti: The obligation to safeguard health-care services
Port-au-Prince, 26 October 2021 — As armed violence continues to rock Haiti, disruptions to fuel supplies are worsening the already dire humanitarian consequences for its people who struggle to access basic services, including health care.Power cuts
04-11-2021 | News release
DigitHarium Month #8: Cyber operations against humanitarian organizations
For the eighth DigitHarium month, we looked at how cyber operations could affect humanitarian organizations and their work: what the stakes were, what risks were most likely to arise, and what steps humanitarian organizations needed to take.For the e
03-11-2021 | Article
IFFIm http://www.iffim.org/ Press Releases/Announcements No new digest content identified. IFRC [to 06 Nov 2021] http://media.ifrc.org/ifrc/news/press-releases/ Selected Press Releases, Announcements
05/11/2021 In the race against the pandemic, the poorest, most vulnerable, and marginalized are being left far behind Statement on COVID-19 vaccine equity from Jagan Chapagain, Secretary General of the International Federation of Red Cross and Red Crescent Societies (IFRC)
“Around half of the world’s population has now received at least one dose of a COVID-19 vaccine. This is a tremendous achievement that even just a year ago seemed unfathomable. However, while richer countries are speeding ahead with vaccination campaigns for their populations, in lower-income countries, only about four per cent of people have received even one dose of a vaccine. Over half of the countries facing humanitarian crises do not have enough doses to vaccinate even ten per cent of their population.
“In the race against the pandemic, the poorest, most vulnerable, and marginalized are being left far behind. It is a humanitarian imperative and a global responsibility, not to mention an economic and recovery necessity, to ensure that everyone has access to vaccines, not only those in countries with the means to buy protection.”
Last week, the UN and the International Red Cross and Red Crescent Movement jointly made five asks to government and the international community, to achieve the equitable distribution and delivery of vaccines.
COVID-19 Responses Could Help Fight Climate Change
WASHINGTON, Nov. 3, 2021 – As the COVID-19 pandemic has overwhelmed health systems worldwide, a new report brings together low-carbon and climate-resilient health solutions that can help protect the planet…
Date: November 03, 2021 Type: Press Release
Supporting Colombian Host Communities and Venezuelan Migrants During the COVID-19 Pandemic
Challenge As of March 2021, an estimated 1.7 million people from Venezuela were based in Colombia— approximately 32 % of all Venezuelan migrants in Latin America. The impact of the crisis is geographically…
Date: October 31, 2021 Type: Result Brief World Customs Organization – WCO [to 06 Nov 2021] http://www.wcoomd.org/ Latest News – Selected Items No new digest content identified. World Organisation for Animal Health (OIE) [to 06 Nov 2021] https://www.oie.int/en/media/news/ Press Releases, Statements No new digest content identified. WTO – World Trade Organisation [to 06 Nov 2021] http://www.wto.org/english/news_e/news_e.htm WTO News and Events No new digest content identified.
International Generic and Biosimilar Medicines Association [IGBA] https://www.igbamedicines.org/ News IGBA Calls on all Stakeholders to Join the Biosimilars Movement on Advancing Access
Geneva, November 1st, 2021 – In the week ahead, IGBA will renew its commitment to the collaborative effort to establish worldwide biosimilar policies that deliver better health outcomes and biologics access equity for more patients. The second Global Biosimilars Week will run from 1st to 5th November 2021 on social media, supported by a dedicated website globalbiosimilarsweek.org
This awareness campaign is open to all stakeholder contributions worldwide and seeks to gather, under one hashtag #globalbiosimilarsweek, useful ideas, experience, information and resources for and from patients, doctors and all other stakeholders across the healthcare community.
“The COVID-19 global health crisis has led governments and the entire healthcare community to rethink and rebuild healthcare systems. This includes focusing on their ability to efficiently deliver access to biologic therapies and to effectively address Non-Communicable Diseases (NCDs),” explained Sudarshan Jain, Chair of the IGBA. “Now is a time to reconcile the unique opportunity provided by the availability of biosimilar medicines and the rising challenges for many patients around the world to access quality-assured transformative therapies. We need to redouble the efforts to effectively tackle NCDs and biosimilar medicines are part of the solution.”
“With 15 years of positive biosimilar medicines contribution to patient health and healthcare system sustainability, the challenges and remedies to efficient use of biosimilar medicines are well known. Our new white paper aims to facilitate experience sharing for communities wanting to Advance Access in their country or region and more importantly to implement effective and tailored strategies in tackling Non-Communicable Diseases locally,” said Julie Maréchal-Jamil, Co-Chair of the IGBA Biosimilars Committee.
IGBA companies are the pioneers and global leaders in the development and marketing of biosimilar medicines. To date there have been more than 400 biosimilar approvals in IGBA’s membership jurisdictions, covering more than 10 therapeutic areas including oncology, rheumatoid arthritis, psoriasis, inflammatory bowel disease, growth disorders, nephrology, fertility, diabetes and ophthalmology.
Journal Watch Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org
Health Care and Homelessness
Homelessness dramatically undermines personal and community health status. Throughout their lifespans, children, elders, and all who are chronically unsheltered confront cumulative health detriments of exposure, violence, and poor nutrition. With limited access to hygiene opportunities and health services, people experiencing homelessness endure poor continuity of care and some of the poorest health outcomes tolerated in the US health care system.
From the Editor Nov 2021 Homelessness Is an Ethical Issue in America
G. Robert Watts, MPH, MS
The National Health Care for the Homeless Council supports clinicians serving 1 million patients per year in 300 Health Care for the Homeless federally qualified health centers and 100 medical respite programs.
AMA J Ethics. 2021;23(11):E835-839. doi: 10.1001/amajethics.2021.835.
Research article Open access Hard choices in artificial intelligence
Roel Dobbe, Thomas Krendl Gilbert, Yonatan Mintz
Article 103555 Abstract
As AI systems are integrated into high stakes social domains, researchers now examine how to design and operate them in a safe and ethical manner. However, the criteria for identifying and diagnosing safety risks in complex social contexts remain unclear and contested. In this paper, we examine the vagueness in debates about the safety and ethical behavior of AI systems. We show how this vagueness cannot be resolved through mathematical formalism alone, instead requiring deliberation about the politics of development as well as the context of deployment. Drawing from a new sociotechnical lexicon, we redefine vagueness in terms of distinct design challenges at key stages in AI system development. The resulting framework of Hard Choices in Artificial Intelligence (HCAI) empowers developers by 1) identifying points of overlap between design decisions and major sociotechnical challenges; 2) motivating the creation of stakeholder feedback channels so that safety issues can be exhaustively addressed. As such, HCAI contributes to a timely debate about the status of AI development in democratic societies, arguing that deliberation should be the goal of AI Safety, not just the procedure by which it is ensured.
Barriers and facilitators to the uptake of new medicines into clinical practice: a systematic review Implementation and uptake of novel and cost-effective medicines can improve patient health outcomes and healthcare efficiency. However, the uptake of new medicines into practice faces a wide range of obstacles. Earlier reviews provided insights into determinants for new medicine uptake (such as medicine, prescriber, patient, organization, and external environment factors). However, the methodological approaches used had limitations (e.g., single author, narrative review, narrow search, no quality assessment of reviewed evidence). This systematic review aims to identify barriers and facilitators affecting the uptake of new medicines into clinical practice and identify areas for future research.
Authors: Kristina Medlinskiene, Justine Tomlinson, Iuri Marques, Sue Richardson, Katherine Stirling and Duncan Petty
Citation: BMC Health Services Research 2021 21:1198
Content type: Research article
Published on: 5 November 2021
Rotavirus gastroenteritis hospitalizations in provinces with different vaccination coverage rates in Spain, 2013–2018 Rotavirus (RV) vaccines are available in Spain since 2006 but are not included in the National Immunization Program. RV vaccination has reached an intermediate vaccination coverage rate (VCR) but with substant…
Authors: J. Ruiz-Contreras, S. Alfayate-Miguelez, B. Carazo-Gallego, E. Onís, L. Díaz-Munilla, M. Mendizabal, M. Méndez Hernández, B. Ferrer-Lorente, M. Unsaín-Mancisidor, J. T. Ramos-Amador, B. Croche-Santander, F. Centeno Malfaz, J. Rodríguez-Suárez, M. Cotarelo, M. San-Martín and J. Arístegui
Citation: BMC Infectious Diseases 2021 21:1138
Content type: Research
Published on: 6 November 2021
Governance frameworks for COVID-19 research ethics review and oversight in Latin America: an exploratory study Research has been an essential part of the COVID-19 pandemic response, including in Latin American (LA) countries. However, implementing research in emergency settings poses the challenge of producing valuable knowledge rapidly while upholding research ethical standards. Research ethics committees (RECs) therefore must conduct timely and rigorous ethics reviews and oversight of COVID-19 research. In the LA region, there is limited knowledge on how countries have responded to this need. To address this gap, the objective of our project is to explore if LA countries developed policies to streamline ethics review and oversight of research in response to the pandemic while ensuring its adherence to ethical standards, and to analyze to what extent these governance frameworks are in accordance with international guidance.
Authors: Ana Palmero, Sarah Carracedo, Noelia Cabrera and Alahí Bianchini
Citation: BMC Medical Ethics 2021 22:147
Content type: Research
Published on: 6 November 2021
Designing a conceptual framework for misinformation on social media: a qualitative study on COVID-19 This study was aimed to present a conceptual framework about the misinformation surrounding COVID-19 outbreak in Iran. For this purpose, discourse analysis of two of the most common social virtual networks wer…
Authors: Peivand Bastani, Seyyed Mostafa Hakimzadeh and Mohammad Amin Bahrami
Citation: BMC Research Notes 2021 14:408
Content type: Research note
Published on: 2 November 2021
The importance of adherence to international standards for depositing open data in public repositories There has been an important global interest in Open Science, which include open data and methods, in addition to open access publications. It has been proposed that public availability of raw data increases th…
Authors: Diego A. Forero, Walter H. Curioso and George P. Patrinos
Citation: BMC Research Notes 2021 14:405
Content type: Commentary
Published on: 2 November 2021
Editorials Harnessing the power of behavioural science to improve health
Elena Altieri, John Grove, Olivia Lawe Davies, Katrine Bach Habersaat, Joseph Okeibunor, Dalia Samhouri, Supriya Bezbaruah
Bull World Health Organ. 2021 Nov 1; 99(11): 754–754A. Published online 2021 Nov 1. doi: 10.2471/BLT.21.287375
PMCID: PMC8542273
Using behavioural science for better health
Tedros Adhanom Ghebreyesus
Bull World Health Organ. 2021 Nov 1; 99(11): 755. Published online 2021 Nov 1. doi: 10.2471/BLT.21.287387
PMCID: PMC8542276
… As members of the broader public health community, we need to get better at listening and observing people and their needs. Doing so requires rigorous collection of behavioural data to understand, for example, how and why our minds take shortcuts, also called heuristics, when information is too much or unclear, or when the right choice is too hard to make.
We also need more information on how people around us influence our decisions, and on how to design environments, services, products and solutions that support, rather than block, behaviours that improve health.
Using behavioural insights is ultimately an act of humility: it requires the community of experts and policy-makers to test each other’s expert knowledge, biases and preferences, and to gather and use behavioural evidence on health-related decisions that all of us, as individuals, make on any given day.
This theme issue of the Bulletin on behavioural sciences for better health provides examples of the work of multidisciplinary teams across the world who have partnered to design interventions that have contributed to improve people’s health. These examples should encourage all those involved in public health to work more systematically in the same direction. Ensuring behaviourally informed strategies, policies and programmes – as opposed to siloed behavioural interventions – is essential to achieving and sustaining better health for all.
Research Insights into vaccine hesitancy from systems thinking, Rwanda
Catherine Decouttere, Stany Banzimana, Pål Davidsen, Carla Van Riet, Corinne Vandermeulen, Elizabeth Mason, Mohammad S Jalali, Nico Vandaele
Bull World Health Organ. 2021 Nov 1; 99(11): 783–794D. Published online 2021 Sep 28. doi: 10.2471/BLT.20.285258
PMCID: PMC8542260
Perspectives Behavioural and social science research opportunities
Maria A Carrasco, Alexandria K Mickler, Ruth Young, Kaitlyn Atkins, Joseph G Rosen, Rafael Obregon
Bull World Health Organ. 2021 Nov 1; 99(11): 834–836. Published online 2021 Aug 31. doi: 10.2471/BLT.20.285370
PMCID: PMC854267
Improving malaria control by understanding human behaviour
April Monroe, Bolanle Olapeju, Sarah Moore, Gabrielle Hunter, Alice Payne Merritt, Fredros Okumu, Stella Babalola
Bull World Health Organ. 2021 Nov 1; 99(11): 837–839. Published online 2021 Sep 30. doi: 10.2471/BLT.20.285369
PMCID: PMC8542269
Healthworker preparedness for COVID-19 management and implementation experiences: a mixed methods study in Uganda’s refugee-hosting districts The negative impact of COVID-19 on population health outcomes raises critical questions on health system preparedness and resilience, especially in resource-limited settings. This study examined healthworker p…
Authors: Gloria Seruwagi, Catherine Nakidde, Felix Otieno, Joshua Kayiwa, Brian Luswata, Eric Lugada, Eric Awich Ochen, Denis Muhangi, Betty Okot, Dunstan Ddamulira, Andrew Masaba and Stephen Lawoko
Citation: Conflict and Health 2021 15:79
Content type: Research
Published on: 3 November 2021
Challenges encountered in comparing international policy responses to COVID-19 and their effects A variety of policies have been implemented around the world in response to the COVID-19 pandemic. This study originally aimed to identify and compare policy responses of different countries and their effects …
Authors: Christine Riley, Bo Xie and Anjum Khurshid
Citation: Health Research Policy and Systems 2021 19:134
Content type: Research
Published on: 30 October 2021
Localisation and local humanitarian action by HPN October 2020
The theme of this edition of Humanitarian Exchange is localisation+ and local humanitarian action. Five years ago this week, donors, United Nations (UN) agencies, non-governmental organisations (NGOs), the International Committee of the Red Cross (ICRC) and International Federation of Red Cross and Red Crescent Societies (IFRC) committed within the Grand Bargain to increase multi-year investments in the institutional capacities of local and national responders, and to provide at least 25% of humanitarian funding to them as directly as possible. Since then, there is increasing consensus at policy and normative level, underscored by the Covid-19 pandemic, that local leadership should be supported. Localisation has gone from a fringe conversation among policy-makers and aid agencies in 2016 to a formal priority under the Grand Bargain. Wider global movements on anti-racism and decolonisation have also brought new momentum to critical reflections on where power, knowledge and capacity reside in the humanitarian system. Yet progress has been slow and major gaps remain between the rhetoric around humanitarian partnerships, funding and coordination and practices on the ground.
Original Investigation Caring for the Critically Ill Patient Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19A Randomized Clinical Trial
Writing Committee for the REMAP-CAP Investigators
free access
JAMA. 2021;326(17):1690-1702. doi:10.1001/jama.2021.18178
This study compares the effect of convalescent plasma vs no convalescent plasma on the outcome of organ support–free days in the hospital among critically ill adults with COVID-19 who had been randomized to the immunoglobulin domain in the ongoing REMAP-CAP trial.
Viewpoint Setting Priorities to Address Research Gaps in Long-term COVID-19 Outcomes in Children
Daniel Munblit, MD, PhD; Louise Sigfrid, MD, PhD; John O. Warner, MBChB, MD
free access
JAMA Pediatr. 2021;175(11):1095-1096. doi:10.1001/jamapediatrics.2021.2281
This Viewpoint describes gaps in research on long-term COVID-19 outcomes in children and provides recommendations to address these gaps.
vaccines and global health :: ethics and policy 