Monthly Archives: January 2022

COVID-19 and Routine Childhood Vaccinations—Identifying Gaps and Informing Solutions

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JAMA Pediatrics
January 2022, Vol 176, No. 1, Pages 7-108
https://jamanetwork.com/journals/jamapediatrics/currentissue

 

COVID-19 and Routine Childhood Vaccinations—Identifying Gaps and Informing Solutions
Brian P. Jenssen, MD, MSHP; Alexander G. Fiks, MD, MSCE
free access
JAMA Pediatr. 2022;176(1):21-23. doi:10.1001/jamapediatrics.2021.4248

Association of the COVID-19 Pandemic With Routine Childhood Vaccination Rates and Proportion Up to Date With Vaccinations Across 8 US Health Systems in the Vaccine Safety Datalink

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JAMA Pediatrics
January 2022, Vol 176, No. 1, Pages 7-108
https://jamanetwork.com/journals/jamapediatrics/currentissue

 

Original Investigation
Association of the COVID-19 Pandemic With Routine Childhood Vaccination Rates and Proportion Up to Date With Vaccinations Across 8 US Health Systems in the Vaccine Safety Datalink
Malini B. DeSilva, MD, MPH; Jacob Haapala, MPH; Gabriela Vazquez-Benitez, PhD; et al.
free access
JAMA Pediatr. 2022;176(1):68-77. doi:10.1001/jamapediatrics.2021.4251
This surveillance study examines the rate of vaccination and proportion of individuals up to date with vaccines in a cohort of 2.8 million children aged 0 to 18 years across 8 US health systems.

Assessment of the Operational Characteristics of Research Ethics Committees in Ghana

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Journal of Empirical Research on Human Research Ethics
Volume 17 Issue 1-2, February-April 2022
http://journals.sagepub.com/toc/jre/current

 
Assessment of the Operational Characteristics of Research Ethics Committees in Ghana
Samuel Asiedu Owusu, Grace Addison, Barbara Redman, Lisa Kearns, Paul Amuna, Amos Laar

 

First Published October 19, 2021; pp. 114–128

A Survey to Determine the Capacity Development Needs of Research Ethics Committee Administrators in South Africa

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Journal of Empirical Research on Human Research Ethics
Volume 17 Issue 1-2, February-April 2022
http://journals.sagepub.com/toc/jre/current

 

A Survey to Determine the Capacity Development Needs of Research Ethics Committee Administrators in South Africa
Mutshidzi A. Mulondo, Joyce M. Tsoka-Gwegweni, Puleng LenkaBula, Perpetual Chikobvu

 

First Published November 22, 2021; pp. 84–93

Human Research Ethics Committee Experiences and Views About Children’s Participation in Research: Results From the MESSI Study

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Journal of Empirical Research on Human Research Ethics
Volume 17 Issue 1-2, February-April 2022
http://journals.sagepub.com/toc/jre/current

 

Empirical Studies on Ethical Issues in Research with Specific Populations
Human Research Ethics Committee Experiences and Views About Children’s Participation in Research: Results From the MESSI Study
Stephanie Taplin, Jenny Chalmers, Judith Brown, Tim Moore, Anne Graham, Morag McArthur
First Published October 12, 2021; pp. 70–83

Marketing authorization of COVID-19 vaccines across UK, EU, and the US: fact-checking and the implications for future research

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Journal of Pharmaceutical Policy and Practice
https://joppp.biomedcentral.com/
[Accessed 08 Jan 2022]

 

Marketing authorization of COVID-19 vaccines across UK, EU, and the US: fact-checking and the implications for future research
While having access to safe and efficient vaccines is essential for eradicating the COVID-19 pandemic, gaining marketing authorisation is a critical step in enabling and speeding this process. On December 2, 2…
Authors: Nasir Abbas and Zaheer-Ud-Din Babar
Citation: Journal of Pharmaceutical Policy and Practice 2021 14:110
Content type: Commentary
Published on: 24 December 2021

Willingness to Get a COVID-19 Vaccine and Reasons for Hesitancy Among Medicare Beneficiaries: Results From a National Survey

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Journal of Public Health Management & Practice
January/February 2022 – Volume 28 – Issue 1
https://journals.lww.com/jphmp/pages/currenttoc.aspx

 

Research Reports
Willingness to Get a COVID-19 Vaccine and Reasons for Hesitancy Among Medicare Beneficiaries: Results From a National Survey
Luo, Huabin; Qu, Haiyan; Basu, Rashmita; More
Journal of Public Health Management and Practice. 28(1):70-76, January/February 2022.

Using Public Deliberation to Set Priorities: The Case of COVID-19 Vaccine Access in New York City

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Journal of Public Health Management & Practice
January/February 2022 – Volume 28 – Issue 1
https://journals.lww.com/jphmp/pages/currenttoc.aspx

 

Using Public Deliberation to Set Priorities: The Case of COVID-19 Vaccine Access in New York City
Scherer, Maya; Kamler, Alexandra; Weiss, Linda; More
Journal of Public Health Management and Practice. 28(1):86-94, January/February 2022.

Dengue during the COVID-19 pandemic

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Journal of Travel Medicine
Volume 28, Issue 8, December 2021
https://academic.oup.com/jtm/issue

 

Editorial
Dengue during the COVID-19 pandemic
Annelies Wilder-Smith, MD
Journal of Travel Medicine, Volume 28, Issue 8, December 2021, taab183, https://doi.org/10.1093/jtm/taab183
Despite coronavirus disease 2019-related disruptions in controlling dengue, efforts need to be maintained to prevent vector-borne diseases during this pandemic. Although travel restrictions brought a global halt to mobility and therefore also a substantial decline of imported and travel-associated dengue, dengue will become dominant again in travel medicine as soon as international travel resumes.

Safety of measles, rubella and mumps vaccines in adults: a prospective cohort study

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Journal of Travel Medicine
Volume 28, Issue 8, December 2021
https://academic.oup.com/jtm/issue

 

Original Articles
Editor’s Choice
Safety of measles, rubella and mumps vaccines in adults: a prospective cohort study
Neuberger Ami, MD, Nadir Eyal, MD, Biber Asaf, MD, Avni Chen, MD, Brom Adi, MD …
Journal of Travel Medicine, Volume 28, Issue 8, December 2021, taab071, https://doi.org/10.1093/jtm/taab071

No further delays in offering booster doses in countries experiencing a major resurgence of COVID-19

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Journal of Travel Medicine
Volume 28, Issue 8, December 2021
https://academic.oup.com/jtm/issue

 

No further delays in offering booster doses in countries experiencing a major resurgence of COVID-19
Benjamin Davido, MD, MSc, Guillaume Davido, MD, MSc, Djillali Annane, MD, PhD
Journal of Travel Medicine, Volume 28, Issue 8, December 2021, taab187, https://doi.org/10.1093/jtm/taab187
Covid booster shots should be proposed and recommended to all fully vaccinated individuals, considering antibody levels are waning over time and that the risk of being infected typically reappears after 6 months.

Feasibility and safety of rVSV-ZEBOV vaccination of humanitarian health workers against Ebola virus disease: an observational study

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Journal of Travel Medicine
Volume 28, Issue 8, December 2021
https://academic.oup.com/jtm/issue

 

Feasibility and safety of rVSV-ZEBOV vaccination of humanitarian health workers against Ebola virus disease: an observational study
Luisa Carnino, MD, Pauline Vetter, MD, Nicolas Peyraud, MD, Sigiriya Aebischer-Perone, MD, François Chappuis, MD, PhD …
Journal of Travel Medicine, Volume 28, Issue 8, December 2021, taab086, https://doi.org/10.1093/jtm/taab086

Conducting mass gathering events during the COVID-19 pandemic: a case study of Kumbh Mela 2021 as a potential ‘super spreader event’

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Journal of Travel Medicine
Volume 28, Issue 8, December 2021
https://academic.oup.com/jtm/issue

 

Conducting mass gathering events during the COVID-19 pandemic: a case study of Kumbh Mela 2021 as a potential ‘super spreader event’
Saurabh Shukla, PhD, Ramsha Khan, M Tech, Yusuf Ahmed, BM, MPH, FRCOG, Ziad A Memish, MD, FRCPC, FACP, FFPH
Journal of Travel Medicine, Volume 28, Issue 8, December 2021, taab160, https://doi.org/10.1093/jtm/taab160

Children and adolescents deserve a better future

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The Lancet
Jan 08, 2022 Volume 399 Number 1032 0p117-210, e1
https://www.thelancet.com/journals/lancet/issue/current

 

Editorial
Children and adolescents deserve a better future
The Lancet
In January, 2020, we announced a Lancet campaign on child and adolescent health. Our intention was to refocus on child mortality, and on the recognition that adolescents matter in global health, at a time when progress had stalled or in some cases reversed amid changing political and environmental circumstances. Little did we know then what the next 2 years would bring.

COVID-19 has been—and still is—a catastrophe for children and young people. In a December report, UNICEF called the pandemic “the biggest threat to children in our 75-year history”. Widespread school and university closures mean that there is now an unprecedented educational and skills deficit globally, with inequities widening and disadvantaged children and adolescents falling even further behind. Digital learning works only for those who have supportive home environments, internet access, and teachers capable of effective online teaching. According to UNICEF, two-thirds of children and young people do not have an internet connection at home…

…National policy makers and the international community have dismally failed to protect children and adolescents during the COVID-19 pandemic. With the new wave of infections with the omicron (B.1.1.529) variant, further school closures are happening again. Vaccination of children is slow at best, with confusing messages and bewildering national differences in recommendations. Clearly, decisions made for our children and young people without their say have been detrimental. Yet, out of such catastrophic times, real transformative change might emerge. Young people want a different world. They want not only to be heard in advocacy roles or have a seat at the table, they want to take part in decision making and policy development. Children in All Policies 2030 (CAP-2030), which aims to put the health and wellbeing of children and adolescents at the centre of sustainable development following the recommendations of a 2020 WHO–UNICEF–Lancet Commission, is helping to give a voice to young people. But a global shift towards true involvement needs much more…

Children and adolescents deserve a better future

Posted on by

The Lancet
Jan 08, 2022 Volume 399 Number 1032 0p117-210, e1
https://www.thelancet.com/journals/lancet/issue/current

 

Editorial
Children and adolescents deserve a better future
The Lancet
In January, 2020, we announced a Lancet campaign on child and adolescent health. Our intention was to refocus on child mortality, and on the recognition that adolescents matter in global health, at a time when progress had stalled or in some cases reversed amid changing political and environmental circumstances. Little did we know then what the next 2 years would bring.

COVID-19 has been—and still is—a catastrophe for children and young people. In a December report, UNICEF called the pandemic “the biggest threat to children in our 75-year history”. Widespread school and university closures mean that there is now an unprecedented educational and skills deficit globally, with inequities widening and disadvantaged children and adolescents falling even further behind. Digital learning works only for those who have supportive home environments, internet access, and teachers capable of effective online teaching. According to UNICEF, two-thirds of children and young people do not have an internet connection at home…

…National policy makers and the international community have dismally failed to protect children and adolescents during the COVID-19 pandemic. With the new wave of infections with the omicron (B.1.1.529) variant, further school closures are happening again. Vaccination of children is slow at best, with confusing messages and bewildering national differences in recommendations. Clearly, decisions made for our children and young people without their say have been detrimental. Yet, out of such catastrophic times, real transformative change might emerge. Young people want a different world. They want not only to be heard in advocacy roles or have a seat at the table, they want to take part in decision making and policy development. Children in All Policies 2030 (CAP-2030), which aims to put the health and wellbeing of children and adolescents at the centre of sustainable development following the recommendations of a 2020 WHO–UNICEF–Lancet Commission, is helping to give a voice to young people. But a global shift towards true involvement needs much more…

Estimating the early impact of the US COVID-19 vaccination programme on COVID-19 cases, emergency department visits, hospital admissions, and deaths among adults aged 65 years and older: an ecological analysis of national surveillance data

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The Lancet
Jan 08, 2022 Volume 399 Number 1032 0p117-210, e1
https://www.thelancet.com/journals/lancet/issue/current

 

Articles
Estimating the early impact of the US COVID-19 vaccination programme on COVID-19 cases, emergency department visits, hospital admissions, and deaths among adults aged 65 years and older: an ecological analysis of national surveillance data
Lucy A McNamara, et al.

Immunogenicity and safety of the human papillomavirus vaccine in young survivors of cancer in the USA: a single-arm, open-label, phase 2, non-inferiority trial

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The Lancet Child & Adolescent Health
Jan 2022 Volume 6 Number 1 p1-70, e1-e4
https://www.thelancet.com/journals/lanchi/issue/current

 

Articles
Immunogenicity and safety of the human papillomavirus vaccine in young survivors of cancer in the USA: a single-arm, open-label, phase 2, non-inferiority trial
Wendy Landier, et al
Young survivors of cancer are at increased risk for cancers that are related to human papillomavirus (HPV), primarily caused by oncogenic HPV types 16 and 18. We aimed to examine the immunogenicity and safety of the three-dose series of HPV vaccine in young survivors of cancer.

A diagonal and social protection plus approach to meet the challenges of the COVID-19 syndemic: cash transfers and intimate partner violence interventions in Latin America

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Lancet Global Health
Jan 2022 Volume 10 Number 1 e1-e153
https://www.thelancet.com/journals/langlo/issue/current

 

A diagonal and social protection plus approach to meet the challenges of the COVID-19 syndemic: cash transfers and intimate partner violence interventions in Latin America
Merike Blofield, et al.

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study

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Lancet Infectious Diseases
Jan 2022 Volume 22 Number 1 p1-150, e1-e40
https://www.thelancet.com/journals/laninf/issue/current

 

Articles
Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study
Michela Antonelli, et al.

Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study

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Lancet Infectious Diseases
Jan 2022 Volume 22 Number 1 p1-150, e1-e40
https://www.thelancet.com/journals/laninf/issue/current

 

Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study
Eric Yuk Fai Wan, et al.

Comparison of the safety and immunogenicity of a novel Matrix-M-adjuvanted nanoparticle influenza vaccine with a quadrivalent seasonal influenza vaccine in older adults: a phase 3 randomised controlled trial

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Lancet Infectious Diseases
Jan 2022 Volume 22 Number 1 p1-150, e1-e40
https://www.thelancet.com/journals/laninf/issue/current

 

Comparison of the safety and immunogenicity of a novel Matrix-M-adjuvanted nanoparticle influenza vaccine with a quadrivalent seasonal influenza vaccine in older adults: a phase 3 randomised controlled trial
Vivek Shinde, et al.

Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial

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Lancet Infectious Diseases
Jan 2022 Volume 22 Number 1 p1-150, e1-e40
https://www.thelancet.com/journals/laninf/issue/current

 

Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial
David Ishola, et al. on behalf of the EBL3001 study group

Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial

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Lancet Infectious Diseases
Jan 2022 Volume 22 Number 1 p1-150, e1-e40
https://www.thelancet.com/journals/laninf/issue/current

 

Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial
Muhammed O Afolabi, et al. on behalf of the EBL3001 study group

Safeguarding people living in vulnerable conditions in the COVID-19 era through universal health coverage and social protection

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Lancet Public Health
Jan 2022 Volume 7 Number 1 e1-e92
https://www.thelancet.com/journals/lanpub/issue/current

 

Viewpoint
Safeguarding people living in vulnerable conditions in the COVID-19 era through universal health coverage and social protection
Gabriela Cuevas Barron, for the Lancet Commission on COVID-19: Task Force on Humanitarian Relief, Social Protection and Vulnerable Groups

Gene drives gaining speed

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Nature Reviews Genetics
Volume 23 Issue 1, January 2022
https://www.nature.com/nrg/volumes/23/issues/1

 

Review Article | 06 August 2021
Gene drives gaining speed
In this Review, Ethan Bier discusses how several impactful technical advancements, particularly involving CRISPR-based methods, are providing a diverse toolkit of gene-drive systems for the control of populations such as insect vectors of disease.
Ethan Bier

Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms

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Nature Reviews Immunology
Volume 22 Issue 1, January 2022
https://www.nature.com/nri/volumes/22/issues/1

 

Review Article | 17 May 2021
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms
This Review discusses evidence from clinical studies and animal models regarding the effects of the gut microbiota on modulating immune responses to vaccination as well as the immunological mechanisms that potentially mediate these effects.
David J. Lynn, Saoirse C. Benson, Bali Pulendran

Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms

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Nature Reviews Immunology
Volume 22 Issue 1, January 2022
https://www.nature.com/nri/volumes/22/issues/1

 

Review Article | 17 May 2021
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms
This Review discusses evidence from clinical studies and animal models regarding the effects of the gut microbiota on modulating immune responses to vaccination as well as the immunological mechanisms that potentially mediate these effects.
David J. Lynn, Saoirse C. Benson, Bali Pulendran

Therapeutic genome editing: regulatory horizons

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Nature Reviews Drug Discovery
Volume 21 Issue 1, January 2022
https://www.nature.com/nrd/volumes/21/issues/1

 

Comment | 29 July 2021
Therapeutic genome editing: regulatory horizons
An increasing number of genome-editing technologies are being developed. Here, we highlight some of the key issues for future therapies using these technologies from a regulatory perspective.
Philip A. Hines, Eleonora Agricola, Ralf Herold

Access to and safety of COVID-19 convalescent plasma in the United States Expanded Access Program: A national registry study

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PLoS Medicine
http://www.plosmedicine.org/
(Accessed 08 Jan 2022)

 

Access to and safety of COVID-19 convalescent plasma in the United States Expanded Access Program: A national registry study
Jonathon W. Senefeld, Patrick W. Johnson, Katie L. Kunze, Evan M. Bloch, Noud van Helmond, Michael A. Golafshar, Stephen A. Klassen, Allan M. Klompas, Matthew A. Sexton, Juan C. Diaz Soto, Brenda J. Grossman, Aaron A. R. Tobian, Ruchika Goel, Chad C. Wiggins, Katelyn A. Bruno, Camille M. van Buskirk, James R. Stubbs, Jeffrey L. Winters, Arturo Casadevall, Nigel S. Paneth, Beth H. Shaz, Molly M. Petersen, Bruce S. Sachais, Matthew R. Buras, Mikolaj A. Wieczorek, Benjamin Russoniello, Larry J. Dumont, Sarah E. Baker, Ralph R. Vassallo, John R. A. Shepherd, Pampee P. Young, Nicole C. Verdun, Peter Marks, N. Rebecca Haley, Robert F. Rea, Louis Katz, Vitaly Herasevich, Dan A. Waxman, Emily R. Whelan, Aviv Bergman, Andrew J. Clayburn, Mary Kathryn Grabowski, Kathryn F. Larson, Juan G. Ripoll, Kylie J. Andersen, Matthew N. P. Vogt, Joshua J. Dennis, Riley J. Regimbal, Philippe R. Bauer, Janis E. Blair, Zachary A. Buchholtz, Michaela C. Pletsch, Katherine Wright, Joel T. Greenshields, Michael J. Joyner, R. Scott Wright, Rickey E. Carter, DeLisa Fairweather
Research Article | published 20 Dec 2021 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003872

Vaccine effectiveness against SARS-CoV-2 infection, hospitalization, and death when combining a first dose ChAdOx1 vaccine with a subsequent mRNA vaccine in Denmark: A nationwide population-based cohort study

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PLoS Medicine
http://www.plosmedicine.org/
(Accessed 08 Jan 2022)

 

Vaccine effectiveness against SARS-CoV-2 infection, hospitalization, and death when combining a first dose ChAdOx1 vaccine with a subsequent mRNA vaccine in Denmark: A nationwide population-based cohort study
Mie Agermose Gram, Jens Nielsen, Astrid Blicher Schelde, Katrine Finderup Nielsen, Ida Rask Moustsen-Helms, Anne Katrine Bjørkholt Sørensen, Palle Valentiner-Branth, Hanne-Dorthe Emborg
Research Article | published 17 Dec 2021 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003874

Characteristics of severely malnourished under-five children immunized with Bacillus Calmette-Guérin following Expanded Programme on Immunization schedule and their outcomes during hospitalization at an urban diarrheal treatment centre, Bangladesh

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PLoS One
http://www.plosone.org/
[Accessed 08 Jan 2022]

 

Research Article
Characteristics of severely malnourished under-five children immunized with Bacillus Calmette-Guérin following Expanded Programme on Immunization schedule and their outcomes during hospitalization at an urban diarrheal treatment centre, Bangladesh
Mst. Mahmuda Ackhter, Abu Sadat Mohammad Sayeem Bin Shahid, Tahmeed Ahmed, Parag Palit, Irin Parvin, Md. Zahidul Islam, Tahmina Alam, Shamsun Nahar Shaima, Lubaba Shahrin, Farzana Afroze, Monira Sarmin, Shoeb Bin Islam, Zubair Akhtar, Mohammod Jobayer Chisti, Fahmida Chowdhury
Research Article | published 07 Jan 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0262391

Immunogenicity and waning immunity from the oral cholera vaccine (Shanchol™) in adults residing in Lukanga Swamps of Zambia

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PLoS One
http://www.plosone.org/
[Accessed 08 Jan 2022]

 

Immunogenicity and waning immunity from the oral cholera vaccine (Shanchol™) in adults residing in Lukanga Swamps of Zambia
Harriet Ng′ombe, Michelo Simuyandi, John Mwaba, Charlie Chaluma Luchen, Peter Alabi, Obvious Nchimunya Chilyabanyama, Cynthia Mubanga, Luiza Miyanda Hatyoka, Mutinta Muchimba, Samuel Bosomprah, Roma Chilengi, Geoffrey Kwenda, Caroline Cleopatra Chisenga
Research Article | published 05 Jan 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0262239

Changes in attitudes to vaccination as a result of the COVID-19 pandemic: A longitudinal study of older adults in the UK

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PLoS One
http://www.plosone.org/
[Accessed 08 Jan 2022]

 

Changes in attitudes to vaccination as a result of the COVID-19 pandemic: A longitudinal study of older adults in the UK
Allyson J. Gallant, Louise A. Brown Nicholls, Susan Rasmussen, Nicola Cogan, David Young, Lynn Williams
Research Article | published 23 Dec 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0261844