Pre-Print Servers

 

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 05 Feb 2022]

Research Article metrics AWAITING PEER REVIEW
Polio health economics: assessing the benefits and costs of polio, non-polio, and integrated activities of the Global Polio Eradication Initiative [version 1; peer review: awaiting peer review]
Kimberly M. Thompson, Dominika A. Kalkowska, Kamran Badizadegan
Peer Reviewers Invited
Funder
Bill and Melinda Gates Foundation
PUBLISHED 03 Feb 2022
Abstract
Background: Investments made by countries and donors to support polio eradication and the Global Polio Eradication Initiative (GPEI) over the past 35 years provided financial support for significant health interventions beyond the prevention of polio. Prior economic analyses that sought to quantify the economic benefits of some interventions encountered insufficient data and evidence associated with non-polio-specific activities. The 2022-2026 GPEI Strategic Plan explicitly identified integration and gender equity as funded mandates that must move forward in parallel with polio eradication, but these goals remain vaguely defined from a health economic perspective.
Methods: To ensure unambiguous and full accounting for all financial investments in the GPEI, polio eradication, and other desirable objectives, we identify the health economic analysis methods and inputs needed to ensure transparent financial accountability and cost-effective use of funds.
Results: Sufficient inputs and methods exist to characterize the health and economic benefits of polio-specific activities, but we identified the need for additional information and method development for some non-polio-specific and cost-sharing activities. Donors who seek to support non-polio-specific objectives as part of the GPEI may want to provide dedicated support financing for which it may be difficult to apply typical health economic criteria and to expect net health and/or net economic benefits.
Conclusions: Given the mixture of funding sources provided to the GPEI, which includes support by governments and private donors, we recommend that the GPEI separately account for financial needs that represent necessities for polio eradication from those used for other stated objectives. An added layer of specificity that identifies all funds according to each activity, the accountable party and/or parties, and the associated measurable health or other outcome(s), will enable improved health economic analyses and reporting to donors who seek to track returns on their investments.

Open Letter metrics
Revised
How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases [version 2; peer review: 2 approved]
Jessica Clark, Wilma A. Stolk, María-Gloria Basáñez, Luc E. Coffeng, Zulma M. Cucunubá, Matthew A. Dixon, Louise Dyson, Katie Hampson, Michael Marks, Graham F. Medley, Timothy M. Pollington, Joaquin M. Prada, Kat S. Rock, Henrik Salje, Jaspreet Toor, T. Déirdre Hollingsworth
Peer Reviewers Angus McLure; Margaret C. Baker
Funders
Bill and Melinda Gates Foundation
UK Foreign, Commonwealth & Development Office
European and Developing Countries Clinical Trials Partnership (EDCTP2) programme
MRC Centre for Global Infectious Disease Analysis
UK Department for International Development
UK Medical Research Council
LATEST VERSION PUBLISHED 02 Feb 2022

 

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…

Measles incidence in South Africa: a six-year review, 2015 – 2020
Mukhlid Yousif, Heather Hong, Susan Malfeld, Sheilagh Smit, Lillian Makhathin, Tshepo Motsamai, Dipolelo Tselana, Morubula Manamela, Mercy Kamupira, Elizabeth Maseti, Kennedy Otwombe, Kerrigan McCarthy, Melinda Suchard
medRxiv 2022.02.03.22270382; doi: https://doi.org/10.1101/2022.02.03.22270382

Transparency and reporting characteristics of COVID-19 randomized controlled trials.
Philipp Kapp, Laura Esmail, Lina Ghosn, Philippe Ravaud, Isabelle Boutron
medRxiv 2022.02.03.22270357; doi: https://doi.org/10.1101/2022.02.03.22270357

Effectiveness of the inactivated COVID-19 vaccine (CoronaVac) in adult population in Indonesia
Anton Suryatma, Raras Anasi, Miko Hananto, Asep Hermawan, Ririn Ramadhany, Irene Lorinda Indalao, Agustiningsih Agustiningsih, Ely Hujjatul Fikriyah, Teti Tejayanti, Rustika Rustika, Kristina Lumban Tobing, Ketut Suarjaya, I Wayan Widia, Pandji Wibawa Dhewantara
medRxiv 2022.02.02.22270351; doi: https://doi.org/10.1101/2022.02.02.22270351

Equitable COVID-19 vaccine prioritization: front-line workers or 65-74 year olds?
Eva Rumpler, Justin M Feldman, Mary T Bassett, Marc Lipsitch
medRxiv 2022.02.03.22270414; doi: https://doi.org/10.1101/2022.02.03.22270414

High Burden of COVID-19 among Unvaccinated Law Enforcement Officers and Firefighters
Alberto J. Caban-Martinez, Manjusha Gaglani, Lauren E.W. Olsho, Lauren Grant, Natasha Schaefer-Solle, Paola Louzado-Feliciano, Harmony L. Tyner, Sarang K. Yoon, Allison L. Naleway, Michael Smith, Brian E. Sokol, Karen Lutrick, Ashley L. Fowlkes, Jennifer Meece, Roger Noriega, Marilyn Odean, Andrew L. Phillips, Holly C. Groom, Kempapura Murthy, Laura J. Edwards, Katherine D. Ellingson, Young M. Yoo, Alexandra Cruz, Karley Respet, Matthew S. Thiese, Jennifer L. Kuntz, Spencer Rose, Louise S. Hadden, Joe K. Gerald, Josephine Mak, Damena Gallimore-Wilson, Jessica Lundgren, Kurt T. Hegmann, Kayan Dunnigan, Meredith G. Wesley, Edward J. Bedrick, Julie Mayo Lamberte, John M. Jones, Angela Hunt, Matthew M. Bruner, Kimberly Groover, Preeta K. Kutty, Addison Testoff, Lindsay B. LeClair, Jini N. Etolue, Mark G. Thompson, Jefferey L. Burgess
medRxiv 2021.11.24.21266396; doi: https://doi.org/10.1101/2021.11.24.21266396

Risk assessment of COVID-19 epidemic resurgence in relation to SARS-CoV-2 variants and vaccination passes
Tyll Krueger, Krzysztof Gogolewski, Marcin Bodych, Anna Gambin, Giulia Giordano, Sarah Cuschieri, Thomas Czypionka, Matjaz Perc, Elena Petelos, Magdalena Rosinska, Ewa Szczurek
medRxiv 2021.05.07.21256847; doi: https://doi.org/10.1101/2021.05.07.21256847 Revision

Is mandatory vaccination in population over 60 adequate to control the COVID-19 pandemic in E.U.?
N.P. Rachaniotis, T.K. Dasaklis, F. Fotopoulos, M. Chouzouris, V. Sypsa, A. Lyberaki, P. Tinios
medRxiv 2022.01.25.22269867; doi: https://doi.org/10.1101/2022.01.25.22269867 Revision

Understanding of and Trust in the Centers for Disease Control and Prevention’s Revised COVID-19 Isolation and Quarantine Guidance Among US Adults
Vishala Mishra, Joseph P. Dexter
medRxiv 2022.02.01.22270288; doi: https://doi.org/10.1101/2022.02.01.22270288

Side Effects of COVID-19 Vaccines and Perceptions about COVID-19 and Its Vaccines in Bangladesh
Md Mohsin, Sultan Mahmud, Ashraf Uddin Mian, Prottay Hasan, Abdul Muyeed, Ariful Islam, Maisha Maliha Rahman, Mahfuza Islam, Md Hasinur Rahaman Khan, M. Shafiqur Rahman
medRxiv 2022.01.31.22270172; doi: https://doi.org/10.1101/2022.01.31.22270172

Wellcome Open Research [to 05 Feb 2022]
https://wellcomeopenresearch.org/browse/articles
[Accessed 05 Feb 2022]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Study Protocol metrics AWAITING PEER REVIEW
Characterising and Addressing the Psychosocial Impact of Tuberculosis in Indonesia (CAPITA): A study protocol [version 1; peer review: awaiting peer review]
Ahmad Fuady, Agus Fitriangga, Agus Sugiharto, Bustanul Arifin, Ferdiana Yunita, Finny Fitry Yani, Helmi Suryani Nasution, I Wayan Gede Artawan Eka Putra, Saidah Rauf, Muchtaruddin Mansyur, Tom Wingfield
Peer Reviewers Invited
Funders
Wellcome Trust
Royal Society of Tropical Medicine and Hygiene
PUBLISHED 04 Feb 2022

Research Article metrics
Revised
10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity [version 3; peer review: 1 approved, 1 approved with reservations]
John W.G. Addy, Yaw Bediako, Francis M. Ndungu, John Joseph Valetta, Adam J. Reid, Jedida Mwacharo, Joyce Mwongeli Ngoi, Joshua Wambua, Edward Otieno, Jennifer Musyoki, Khadija Said, Matthew Berriman, Kevin Marsh, Philip Bejon, Mario Recker, Jean Langhorne
Peer Reviewers Rodrigo M Corder; Rhea J Longley
Funders
Wellcome Trust
Francis Crick Institute
Medical Research Council
LATEST VERSION PUBLISHED 04 Feb 2022

Research Article metrics AWAITING PEER REVIEW
“An increase in COVID-19 patients would be overwhelming”: A qualitative description of healthcare workers’ experiences during the first wave of COVID-19 (March 2020 to October 2020) at Malawi’s largest referral hospital. [version 1; peer review: awaiting peer review]
Felix Limbani, Blessings M Kapumba, Henry Mzinganjira, Tamara Phiri, Henry C Mwandumba, Jamie Rylance, Ben Morton, Nicola Desmond
Peer Reviewers Invited
Funder
Wellcome Trust
PUBLISHED 04 Feb 2022

Research Article metrics
Revised
Sensitivity of RT-PCR testing of upper respiratory tract samples for SARS-CoV-2 in hospitalised patients: a retrospective cohort study [version 2; peer review: 2 approved]
Thomas C. Williams, Elizabeth Wastnedge, Gina McAllister, Ramya Bhatia, Kate Cuschieri, Kallirroi Kefala, Fiona Hamilton, Ingólfur Johannessen, Ian F. Laurenson, Jill Shepherd, Alistair Stewart, Donald Waters, Helen Wise, Kate E. Templeton
Peer Reviewers James Otieno; Mariska M.G. Leeflang
Funder
Wellcome Trust
LATEST VERSION PUBLISHED 01 Feb 2022