Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

Posted on by

Science Translational Medicine
Volume 14| Issue 630| 2 Feb 2022
https://www.science.org/toc/stm/current

 

Research Articles
Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains
BY Baoling Ying, et al
02 Feb 2022
Open Access
mRNA-1273–based vaccines protect against historical and variant SARS-CoV-2 strains in 129S2 and K18-hACE2 mice.
Abstract
Although mRNA vaccines encoding the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prevent COVID-19, the emergence of new viral variants jeopardizes their efficacy. Here, we assessed the immunogenicity and protective …