SARS-CoV-2 infections in children: Understanding diverse outcomes

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Immunity
Feb 08, 2022 Volume 55 Issue 2 p185-376
https://www.cell.com/immunity/current

 

Perspective
SARS-CoV-2 infections in children: Understanding diverse outcomes
Petter Brodin
Open Access
Brodin summarizes the current understanding of immune responses to SARS-CoV-2 infections in children and the possible explanations for the overall milder COVID-19 disease in young versus older individuals. To explain the combined observations to date, Brodin proposes an energy allocation perspective to explain mild disease, viral dynamics, and MIS-C in children and young people.