Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

Article | 23 December 2021
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Pseudovirus assays and surface plasmon resonance show that the Omicron receptor-binding domain binds to human ACE2 with increased affinity relative to the ancestral virus, and that most neutralizing antibodies are considerably less potent against Omicron.
Elisabetta Cameroni, John E. Bowen, Davide Corti