Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 05 Mar 2022]

[No new digest content identified]

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…

Precision recruitment for high-risk participants in a COVID-19 research study
Aziz Mezlini, Eamon Caddigan, Allison Shapiro, Ernesto Ramirez, Helena Kondow-McConaghy, Justin Yang, Kerry DeMarco, Pejman Naraghi-Arani, Luca Foschini
medRxiv 2022.03.03.22271504; doi: https://doi.org/10.1101/2022.03.03.22271504

Impact of Population Mixing Between a Vaccinated Majority and Unvaccinated Minority on Disease Dynamics. Implications for SARS-CoV-2
Ashleigh Tuite, Afia Amoako, David Fisman
medRxiv 2021.12.14.21267742; doi: https://doi.org/10.1101/2021.12.14.21267742

Determinants of COVID-19 vaccine acceptability in Mozambique: the role of institutional trust
Bo Hu, Wei Yang, Paul Alexandre Bouanchaud, Yolanda Chongo, Jennifer Wheeler, Sergio Chicumbe, Marcos Chissano
medRxiv 2022.03.03.22271828; doi: https://doi.org/10.1101/2022.03.03.22271828
Abstract
Background Vaccination plays an imperative role in protecting public health and preventing avoidable mortality. Yet, the reasons for vaccine hesitancy are not well understood. This study investigates the factors associated with the acceptability of COVID-19 vaccine in Mozambique. Methods The data came from the three waves of the COVID-19 Knowledge, Attitudes and Practices (KAP) survey which followed a cohort of 1,371 adults in Mozambique over three months (N=3,809). Data collection was through a structured questionnaire using telephone interviewing (CAPI). Multilevel regression analysis was conducted to identify the trajectories of, and the factors associated with COVID-19 vaccine acceptability. Results There was great volatility in COVID-19 vaccine acceptability over time. Institutional trust was consistently and strongly correlated with different measures of vaccine acceptability. There was a greater decline in vaccine acceptability in people with lower institutional trust. The positive correlation between institutional trust and vaccine acceptability was stronger in younger than older adults. Vaccine acceptability also varied by gender and marital status. Conclusions Vaccine acceptability is sensitive to news and information circulated in the public domain. Institutional trust is a central driver of vaccine acceptability and contributes to the resilience of the health system. Our study highlights the importance of health communication and building a trustful relationship between the general public and public institutions in the context of a global pandemic.

Acute and long-term impacts of COVID-19 on economic vulnerability: a population-based longitudinal study (COVIDENCE UK)
Anne E Williamson, Florence Tydeman, Alec Miners, Kate Pyper, Adrian R Martineau
medRxiv 2022.03.03.22271835; doi: https://doi.org/10.1101/2022.03.03.22271835

An observational study of the association between COVID-19 vaccination rates and participation in a vaccine lottery
Dajung Jun, Anthony Scott
medRxiv 2022.03.02.22271734; doi: https://doi.org/10.1101/2022.03.02.22271734
Abstract
Objectives Are financial incentives from entry in a vaccine lottery associated with a higher probability of vaccination for COVID-19? Design A cross-sectional study with adjustment for covariates using logistic regression Setting October and November 2021, Australia. Participants 2,375 respondents of the Taking the Pulse of the Nation Survey Interventions Participation in the Million Dollar Vaccination Lottery Primary and secondary outcome measures The proportion of respondents who had any vaccination, a first dose only, or second dose compared to all other respondents Results Those who participated in the lottery were 2.27 times more likely to be vaccinated after the lottery opened on October 1st than those who did not. This was driven by those receiving second doses. Lottery participants were 1.38 times more likely to receive their first dose after October 1st and 2.31 times more likely to receive their second dose after October 1st. Conclusions Lottery participation is associated with a higher vaccination rate, with this effect dominated by a higher rate of second doses. There is a smaller insignificant difference for those receiving a first dose, suggesting lotteries may not be as effective at reducing vaccine hesitancy, compared to ‘nudging’ people to get their second dose more quickly.

Prevalence of Chronic Diseases, Depression, and Stress among U.S. Child Care Professionals during the COVID-19 Pandemic
Jad A. Elharake, Mehr Shafiq, Ayse Cobanoglu, Amyn A. Malik, Madeline Klotz, John Eric Humphries, Thomas Murray, Kavin M. Patel, David Wilkinson, Inci Yildirim, Rachel Diaz, Rosalia Rojas, Anael Kuperwajs Cohen, Aiden Lee, Chin R. Reyes, Saad B. Omer, Walter S. Gilliam
medRxiv 2022.03.01.22271717; doi: https://doi.org/10.1101/2022.03.01.22271717

The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization
Amy B. Karger, James D. Brien, Jayne M. Christen, Santosh Dhakal, Troy J. Kemp, Sabra L. Klein, Ligia A. Pinto, Lakshmanane Premkumar, John D. Roback, Raquel A. Binder, Karl W. Boehme, Suresh Boppana, James M. Crawford, John L. Daiss, Alan P. Dupuis II, Ana M. Espino, Catherine Forconi, J. Craig Forrest, Roxie C. Girardin, Douglas A. Granger, Steve W. Granger, Natalie S. Haddad, Christopher D. Heaney, Danielle T. Hunt, Joshua L. Kennedy, Christopher L. King, Kate Kruczynski, Joshua LaBaer, F. Eun-Hyung Lee, William T. Lee, Shan-Lu Liu, Gerard Lozanski, Todd Lucas, Ann M. Moormann, Vel Murugan, Nkemakonam C. Okoye, Petraleigh Pantoja, Anne F. Payne, Jin Park, Swetha Pinninti, Amelia K. Pinto, Nora Pisanic, Ji Qiu, Carlos A. Sariol, Lusheng Song, Tara L. Steffen, E. Taylor Stone, Linda M. Styer, Mehul S. Suthar, Stefani N. Thomas, Bharat Thyagarajan, Jennifer L. Yates, Kimia Sobhani
medRxiv 2022.02.27.22271399; doi: https://doi.org/10.1101/2022.02.27.22271399

Racial/Ethnic Disparities in the Observed COVID-19 Case Fatality Rate Among the U.S. Population
L. Philip Schumm, Mihai C. Giurcanu, Kenneth J. Locey, Jean Czerlinski Ortega, Zhenyu Zhang, Robert L. Grossman
medRxiv 2022.03.01.22271708; doi: https://doi.org/10.1101/2022.03.01.22271708

Healthcare services access, use, and barriers among migrants in Europe: a systematic review
Petros Galanis, Koureas Spyros, Olga Siskou, Olympia Konstantakopoulou, Georgios Angelopoulos, Daphne Kaitelidou
medRxiv 2022.02.24.22271449; doi: https://doi.org/10.1101/2022.02.24.22271449

Assessing the Burden of COVID-19 in Developing Countries: Systematic Review, Meta-Analysis, and Public Policy Implications
Andrew Levin, Nana Owusu-Boaitey, Sierra Pugh, Bailey K. Fosdick, Anthony B. Zwi, Anup Malani, Satej Soman, Lonni Besançon, Ilya Kashnitsky, Sachin Ganesh, Aloysius McLaughlin, Gayeong Song, Rine Uhm, Daniel Herrera-Esposito, Gustavo de los Campos, Ana Carolina Pecanha Antiono, Enyew Birru Tadese, Gideon Meyerowitz-Katz
medRxiv 2021.09.29.21264325; doi: https://doi.org/10.1101/2021.09.29.21264325

Vaccine hesitancy strongly correlates with COVID-19 deaths underreporting
Adam Sobieszek, Miriam Lipniacka, Tomasz Lipniacki
medRxiv 2022.02.27.22271579; doi: https://doi.org/10.1101/2022.02.27.22271579

Genomic surveillance of SARS-CoV-2 in a university community: insights into tracking variants, transmission, and spread of Gamma (P.1) variant
Ilinca I. Ciubotariu, Jack Dorman, Nicole M. Perry, Lev Gorenstein, Jobin J. Kattoor, Abebe A. Fola, Amy Zine, G. Kenitra Hendrix, Rebecca P. Wilkes, Andrew Kitchen, Giovanna Carpi
medRxiv 2022.02.25.22271521; doi: https://doi.org/10.1101/2022.02.25.22271521

SARS-CoV-2 mRNA Vaccination-Associated Myocarditis in Children Ages 12-17: A Stratified National Database Analysis
Tracy Beth Høeg, Allison Krug, Josh Stevenson, John Mandrola
medRxiv 2021.08.30.21262866; doi: https://doi.org/10.1101/2021.08.30.21262866

Wellcome Open Research [to 05 Mar 2022]
https://wellcomeopenresearch.org/browse/articles
[Accessed 05 Mar 2022]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Method Article metrics
Revised
An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams [version 2; peer review: 1 approved, 1 approved with reservations]
Khadija Said Mohammed, Zaydah R. de Laurent, Donwilliams O. Omuoyo, Clement Lewa, Elijah Gicheru, Robinson Cheruiyot, Brian Bartilol, Shadrack Mutua, Jennifer Musyoki, Horace Gumba, Jedidah Mwacharo, Debra Riako, Shaban J. Mwangi, Bonface M. Gichuki, Lydia Nyamako, Angela Karani, Henry Karanja, Daisy Mugo, John N. Gitonga, Susan Njuguna, Wilson Gumbi, Brian Tawa, Metrine Tendwa, Wesley Cheruiyot, Yiakon Sein, John K. Nyambu, Shem O. Patta, Thani Suleiman Thani, Eric K. Maitha, Benson Kitole, Mohamed S. Mwakinangu, Barke S. Muslih, John Ochieng Otieno, Joyce U. Nyiro, Patience Kiyuka, Leonard Ndwiga, Kevin Wamae, Domtila Kimani, Johnstone Makale, John Mwita Morobe, Victor Osoti, Arnold W. Lambisia, Calleb Odundo, Salim Mwarumba, Martin Mutunga, Philip Bejon, Benjamin Tsofa, Charles N. Agoti, Lynette Isabella Ochola-Oyier
Peer Reviewers Davis Nwakanma; Esther Omuseni and John Waitumbi
Funders
Wellcome Trust
DELTAS Africa Initiative
PATH
National Institute for Health Research
Department for International Development, UK Government
LATEST VERSION PUBLISHED 04 Mar 2022

Research Article metrics AWAITING PEER REVIEW
Pandemic preparedness and responsiveness of research review committees: lessons from review of COVID-19 protocols at KEMRI Wellcome Trust Research Programme in Kenya [version 1; peer review: awaiting peer review]
Alex Hinga, Lisha Jeena, Esther Awuor, Jane Kahindi, Marianne Munene, Samson Kinyanjui, Sassy Molyneux, Vicki Marsh, Dorcas Kamuya
Peer Reviewers Invited
Funders
Wellcome Trust
African Academy of Sciences
PUBLISHED 03 Mar 2022

Research Article metrics AWAITING PEER REVIEW
Health care users’ acceptance of broad consent for storage of biological materials and associated data for research purposes in Uganda [version 1; peer review: awaiting peer review]
Hellen Nansumba, Mugalula Flaviano, Semanda Patrick, Ssewanyana Isaac, Douglas Wassenaar
Peer Reviewers Invited
Funder
Wellcome Trust
PUBLISHED 01 Mar 2022

Pre-Print Servers

 

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 05 Mar 2022]

[No new digest content identified]

 

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…

Precision recruitment for high-risk participants in a COVID-19 research study
Aziz Mezlini, Eamon Caddigan, Allison Shapiro, Ernesto Ramirez, Helena Kondow-McConaghy, Justin Yang, Kerry DeMarco, Pejman Naraghi-Arani, Luca Foschini
medRxiv 2022.03.03.22271504; doi: https://doi.org/10.1101/2022.03.03.22271504

Impact of Population Mixing Between a Vaccinated Majority and Unvaccinated Minority on Disease Dynamics. Implications for SARS-CoV-2
Ashleigh Tuite, Afia Amoako, David Fisman
medRxiv 2021.12.14.21267742; doi: https://doi.org/10.1101/2021.12.14.21267742

Determinants of COVID-19 vaccine acceptability in Mozambique: the role of institutional trust
Bo Hu, Wei Yang, Paul Alexandre Bouanchaud, Yolanda Chongo, Jennifer Wheeler, Sergio Chicumbe, Marcos Chissano
medRxiv 2022.03.03.22271828; doi: https://doi.org/10.1101/2022.03.03.22271828
Abstract
Background Vaccination plays an imperative role in protecting public health and preventing avoidable mortality. Yet, the reasons for vaccine hesitancy are not well understood. This study investigates the factors associated with the acceptability of COVID-19 vaccine in Mozambique. Methods The data came from the three waves of the COVID-19 Knowledge, Attitudes and Practices (KAP) survey which followed a cohort of 1,371 adults in Mozambique over three months (N=3,809). Data collection was through a structured questionnaire using telephone interviewing (CAPI). Multilevel regression analysis was conducted to identify the trajectories of, and the factors associated with COVID-19 vaccine acceptability. Results There was great volatility in COVID-19 vaccine acceptability over time. Institutional trust was consistently and strongly correlated with different measures of vaccine acceptability. There was a greater decline in vaccine acceptability in people with lower institutional trust. The positive correlation between institutional trust and vaccine acceptability was stronger in younger than older adults. Vaccine acceptability also varied by gender and marital status. Conclusions Vaccine acceptability is sensitive to news and information circulated in the public domain. Institutional trust is a central driver of vaccine acceptability and contributes to the resilience of the health system. Our study highlights the importance of health communication and building a trustful relationship between the general public and public institutions in the context of a global pandemic.

Acute and long-term impacts of COVID-19 on economic vulnerability: a population-based longitudinal study (COVIDENCE UK)
Anne E Williamson, Florence Tydeman, Alec Miners, Kate Pyper, Adrian R Martineau
medRxiv 2022.03.03.22271835; doi: https://doi.org/10.1101/2022.03.03.22271835

An observational study of the association between COVID-19 vaccination rates and participation in a vaccine lottery
Dajung Jun, Anthony Scott
medRxiv 2022.03.02.22271734; doi: https://doi.org/10.1101/2022.03.02.22271734
Abstract
Objectives Are financial incentives from entry in a vaccine lottery associated with a higher probability of vaccination for COVID-19? Design A cross-sectional study with adjustment for covariates using logistic regression Setting October and November 2021, Australia. Participants 2,375 respondents of the Taking the Pulse of the Nation Survey Interventions Participation in the Million Dollar Vaccination Lottery Primary and secondary outcome measures The proportion of respondents who had any vaccination, a first dose only, or second dose compared to all other respondents Results Those who participated in the lottery were 2.27 times more likely to be vaccinated after the lottery opened on October 1st than those who did not. This was driven by those receiving second doses. Lottery participants were 1.38 times more likely to receive their first dose after October 1st and 2.31 times more likely to receive their second dose after October 1st. Conclusions Lottery participation is associated with a higher vaccination rate, with this effect dominated by a higher rate of second doses. There is a smaller insignificant difference for those receiving a first dose, suggesting lotteries may not be as effective at reducing vaccine hesitancy, compared to ‘nudging’ people to get their second dose more quickly.

Prevalence of Chronic Diseases, Depression, and Stress among U.S. Child Care Professionals during the COVID-19 Pandemic
Jad A. Elharake, Mehr Shafiq, Ayse Cobanoglu, Amyn A. Malik, Madeline Klotz, John Eric Humphries, Thomas Murray, Kavin M. Patel, David Wilkinson, Inci Yildirim, Rachel Diaz, Rosalia Rojas, Anael Kuperwajs Cohen, Aiden Lee, Chin R. Reyes, Saad B. Omer, Walter S. Gilliam
medRxiv 2022.03.01.22271717; doi: https://doi.org/10.1101/2022.03.01.22271717

The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization
Amy B. Karger, James D. Brien, Jayne M. Christen, Santosh Dhakal, Troy J. Kemp, Sabra L. Klein, Ligia A. Pinto, Lakshmanane Premkumar, John D. Roback, Raquel A. Binder, Karl W. Boehme, Suresh Boppana, James M. Crawford, John L. Daiss, Alan P. Dupuis II, Ana M. Espino, Catherine Forconi, J. Craig Forrest, Roxie C. Girardin, Douglas A. Granger, Steve W. Granger, Natalie S. Haddad, Christopher D. Heaney, Danielle T. Hunt, Joshua L. Kennedy, Christopher L. King, Kate Kruczynski, Joshua LaBaer, F. Eun-Hyung Lee, William T. Lee, Shan-Lu Liu, Gerard Lozanski, Todd Lucas, Ann M. Moormann, Vel Murugan, Nkemakonam C. Okoye, Petraleigh Pantoja, Anne F. Payne, Jin Park, Swetha Pinninti, Amelia K. Pinto, Nora Pisanic, Ji Qiu, Carlos A. Sariol, Lusheng Song, Tara L. Steffen, E. Taylor Stone, Linda M. Styer, Mehul S. Suthar, Stefani N. Thomas, Bharat Thyagarajan, Jennifer L. Yates, Kimia Sobhani
medRxiv 2022.02.27.22271399; doi: https://doi.org/10.1101/2022.02.27.22271399

Racial/Ethnic Disparities in the Observed COVID-19 Case Fatality Rate Among the U.S. Population
L. Philip Schumm, Mihai C. Giurcanu, Kenneth J. Locey, Jean Czerlinski Ortega, Zhenyu Zhang, Robert L. Grossman
medRxiv 2022.03.01.22271708; doi: https://doi.org/10.1101/2022.03.01.22271708

Healthcare services access, use, and barriers among migrants in Europe: a systematic review
Petros Galanis, Koureas Spyros, Olga Siskou, Olympia Konstantakopoulou, Georgios Angelopoulos, Daphne Kaitelidou
medRxiv 2022.02.24.22271449; doi: https://doi.org/10.1101/2022.02.24.22271449

Assessing the Burden of COVID-19 in Developing Countries: Systematic Review, Meta-Analysis, and Public Policy Implications
Andrew Levin, Nana Owusu-Boaitey, Sierra Pugh, Bailey K. Fosdick, Anthony B. Zwi, Anup Malani, Satej Soman, Lonni Besançon, Ilya Kashnitsky, Sachin Ganesh, Aloysius McLaughlin, Gayeong Song, Rine Uhm, Daniel Herrera-Esposito, Gustavo de los Campos, Ana Carolina Pecanha Antiono, Enyew Birru Tadese, Gideon Meyerowitz-Katz
medRxiv 2021.09.29.21264325; doi: https://doi.org/10.1101/2021.09.29.21264325

Vaccine hesitancy strongly correlates with COVID-19 deaths underreporting
Adam Sobieszek, Miriam Lipniacka, Tomasz Lipniacki
medRxiv 2022.02.27.22271579; doi: https://doi.org/10.1101/2022.02.27.22271579

Genomic surveillance of SARS-CoV-2 in a university community: insights into tracking variants, transmission, and spread of Gamma (P.1) variant
Ilinca I. Ciubotariu, Jack Dorman, Nicole M. Perry, Lev Gorenstein, Jobin J. Kattoor, Abebe A. Fola, Amy Zine, G. Kenitra Hendrix, Rebecca P. Wilkes, Andrew Kitchen, Giovanna Carpi
medRxiv 2022.02.25.22271521; doi: https://doi.org/10.1101/2022.02.25.22271521

SARS-CoV-2 mRNA Vaccination-Associated Myocarditis in Children Ages 12-17: A Stratified National Database Analysis
Tracy Beth Høeg, Allison Krug, Josh Stevenson, John Mandrola
medRxiv 2021.08.30.21262866; doi: https://doi.org/10.1101/2021.08.30.21262866

Wellcome Open Research [to 05 Mar 2022]
https://wellcomeopenresearch.org/browse/articles
[Accessed 05 Mar 2022]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Method Article metrics
Revised
An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams [version 2; peer review: 1 approved, 1 approved with reservations]
Khadija Said Mohammed, Zaydah R. de Laurent, Donwilliams O. Omuoyo, Clement Lewa, Elijah Gicheru, Robinson Cheruiyot, Brian Bartilol, Shadrack Mutua, Jennifer Musyoki, Horace Gumba, Jedidah Mwacharo, Debra Riako, Shaban J. Mwangi, Bonface M. Gichuki, Lydia Nyamako, Angela Karani, Henry Karanja, Daisy Mugo, John N. Gitonga, Susan Njuguna, Wilson Gumbi, Brian Tawa, Metrine Tendwa, Wesley Cheruiyot, Yiakon Sein, John K. Nyambu, Shem O. Patta, Thani Suleiman Thani, Eric K. Maitha, Benson Kitole, Mohamed S. Mwakinangu, Barke S. Muslih, John Ochieng Otieno, Joyce U. Nyiro, Patience Kiyuka, Leonard Ndwiga, Kevin Wamae, Domtila Kimani, Johnstone Makale, John Mwita Morobe, Victor Osoti, Arnold W. Lambisia, Calleb Odundo, Salim Mwarumba, Martin Mutunga, Philip Bejon, Benjamin Tsofa, Charles N. Agoti, Lynette Isabella Ochola-Oyier
Peer Reviewers Davis Nwakanma; Esther Omuseni and John Waitumbi
Funders
Wellcome Trust
DELTAS Africa Initiative
PATH
National Institute for Health Research
Department for International Development, UK Government
LATEST VERSION PUBLISHED 04 Mar 2022

Research Article metrics AWAITING PEER REVIEW
Pandemic preparedness and responsiveness of research review committees: lessons from review of COVID-19 protocols at KEMRI Wellcome Trust Research Programme in Kenya [version 1; peer review: awaiting peer review]
Alex Hinga, Lisha Jeena, Esther Awuor, Jane Kahindi, Marianne Munene, Samson Kinyanjui, Sassy Molyneux, Vicki Marsh, Dorcas Kamuya
Peer Reviewers Invited
Funders
Wellcome Trust
African Academy of Sciences
PUBLISHED 03 Mar 2022

Research Article metrics AWAITING PEER REVIEW
Health care users’ acceptance of broad consent for storage of biological materials and associated data for research purposes in Uganda [version 1; peer review: awaiting peer review]
Hellen Nansumba, Mugalula Flaviano, Semanda Patrick, Ssewanyana Isaac, Douglas Wassenaar
Peer Reviewers Invited
Funder
Wellcome Trust
PUBLISHED 01 Mar 2022