U.S.: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

U.S.: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

 

 

HHS
News
No new digest content identified.

 

BARDA-ASPR – U.S. Department of HHS [to 16 Apr 2022]
https://aspr.hhs.gov/newsroom/Pages/NewsRoomHome.aspx
News
Renewal of the Determination that a Public Health Emergency Exists Nationwide as the Result of the Continued Consequences of Coronavirus Disease 2019 (COVID-19) Pandemic
Tuesday, April 12, 2022

 

 

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FDA
Press Announcements

FDA Takes Important Steps to Increase Racial and Ethnic Diversity in Clinical Trials
Agency’s Focus on Inclusion in Trials for All Medical Products Aligns with Biden Administration’s Cancer Moonshot Goal of Addressing Inequities and Beyond
April 13, 2022
Today, the U.S. Food and Drug Administration issued a new draft guidance to industry for developing plans to enroll more participants from underrepresented racial and ethnic populations in the U.S. into clinical trials –  expanding on the agency’s previous guidances for industry to improve clinical trial diversity.

“The U.S. population has become increasingly diverse, and ensuring meaningful representation of racial and ethnic minorities in clinical trials for regulated medical products is fundamental to public health,” said FDA Commissioner Robert M. Califf, M.D. “Going forward, achieving greater diversity will be a key focus throughout the FDA to facilitate the development of better treatments and better ways to fight diseases that often disproportionately impact diverse communities. This guidance also further demonstrates how we support the Administration’s Cancer Moonshot goal of addressing inequities in cancer care, helping to ensure that every community in America has access to cutting-edge cancer diagnostics, therapeutics and clinical trials.”

Despite having a disproportionate burden for certain diseases, racial and ethnic minorities are frequently underrepresented in biomedical research. Clinical trials provide a crucial base of evidence for evaluating whether a medical product is safe and effective; therefore, enrollment in clinical trials should reflect the diversity of the population that is ultimately going to use the treatment. It is known that biological differences exist in how people respond to certain therapies. For example, variations in genetic coding can make a treatment more or less toxic for one racial or ethnic group than another. These variations can also make drugs like antidepressants and blood-pressure medications less effective for certain groups.

This draft guidance, “Diversity Plans to Improve Enrollment of Participants from Underrepresented Racial and Ethnic Subgroups in Clinical Trials,” recommends that sponsors of medical products develop and submit a Race and Ethnicity Diversity Plan to the agency early in clinical development, based on a framework outlined in the guidance…

Regulatory Actions
Vaccines and Related Biological Products Advisory Committee– FDA
https://www.fda.gov/advisory-committees/blood-vaccines-and-other-biologics/vaccines-and-related-biological-products-advisory-committee
Calendar
No new calendar dates identified.

 

 

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White House [U.S.] [to 16 Apr 2022]
Briefing Room – Selected Major COVID Announcements
Press Statement – COVID Context
No new digest content identified.

 

U.S. Department of State [to 16 Apr 2022]
https://www.state.gov/coronavirus/releases/
Press Statement – COVID Context
No new digest content identified.

 

USAID [to 16 Apr 2022]
https://www.usaid.gov/news-information/press-releases
Selected Press Releases, Statements, Announcements
USAID Announces New Programs to Protect Our Ocean
April 14, 2022
Press Release
The U.S. Agency for International Development (USAID) announced 24 initiatives to protect our ocean at the Our Ocean Conference 2022 in Palau.

USAID Announces $18 Million Contribution to Education Cannot Wait
April 13, 2022
Press Release
The U.S. Agency for International Development (USAID) will contribute an additional $18 million to Education Cannot Wait (ECW), the major global fund for education in emergencies. USAID announced the additional funding during ECW’s scoping visit to Moldova to support the response to the crisis in Ukraine.

USAID and LIXIL Announce $10 Million to Confront the Global Sanitation Crisis
April 12, 2022
Today, the U.S. Agency for International Development and LIXIL, a global housing and sanitation products multinational company, launched the Partnership for Better Living to expand access to affordable sanitation and hygiene solutions for the underserved in up to 11 countries across sub-Saharan Africa and Asia by 2026.

Europe: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

Europe: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

 

 

European Medicines Agency
News & Press Releases
Press Releases
[No new digest content identified]

 

 

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European Centre for Disease Prevention and Control
https://www.ecdc.europa.eu/en
Latest Updates [Selected]
[No new digest content identified]

 

 

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Accessed 16 Apr 2022
https://vaccinetracker.ecdc.europa.eu/public/extensions/COVID-19/vaccine-tracker.html#uptake-tab

 

 

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European Commission
https://ec.europa.eu/commission/presscorner/home/en
Latest [Selected]
Press release 14 April 2022
Green Deal: EU announces €1 billion worth of commitments to protect the ocean
Today, at the Our Ocean Conference (OOC) in Palau, the EU has renewed its pledges towards international Ocean governance.

Press release 12 April 2022
Ukraine: EU humanitarian operation in the Republic of Moldova enhances assistance for refugees
Since the start of Russia’s invasion on 24 February, the refugee influx of civilians fleeing Ukraine to reach neighbouring countries has resulted in skyrocketing humanitarian needs.

Press release 9 April 2022
Stand Up For Ukraine: €9.1 billion pledged in support of internally displaced and refugees
The “Stand Up for Ukraine” global pledging event and campaign has raised €9.1 billion for people fleeing the Russian invasion, inside Ukraine and abroad, including €1 billion from the European Commission.

India: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

India: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

 

 

Ministry of Health and Family Welfare
https://www.mohfw.gov.in/

 

 

Government of India – Press Information Bureau
Latest Press Releases
COVID – 19 Vaccination Update – Day 456
:: India’s cumulative vaccination coverage crosses 186.49 Crore
:: More than 11 lakh Vaccine doses administered today till 7 pm
:: More than 2.42 Crore Vaccine Doses administered to 12-14 age group so far
Posted On: 16 APR 2022 8:05PM by PIB Delhi

 

 

Indian Council for Medical Research (ICMR)
https://www.icmr.gov.in/media.html
Press Releases
No new digest content identified.

China: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

China: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment

[We did not identify official announcements about Shanghai confirming the reports below; See China CDC below for additional announcements]

China tightens controls as Shanghai reports record Covid cases
Japan urges local government to address business concerns as ongoing restrictions hit commerce
Reuters in Shanghai
Sat 16 Apr 2022 10.42 EDT
Shanghai reported a record number of symptomatic Covid-19 cases on Saturday and other areas across China tightened controls as the country kept up its “dynamic clearance” approach that aims to stamp out the highly transmissible Omicron variant.

The Zhengzhou airport economic zone, a central Chinese manufacturing area that includes Apple supplier Foxconn, announced a 14-day lockdown on Friday “to be adjusted according to the epidemic situation”…

…Shanghai itself, which is at the centre of China’s recent Covid surge starting in early March, reported a record 3,590 symptomatic cases for 15 April, as well as 19,923 asymptomatic cases. The asymptomatic case number was up slightly from 19,872 cases a day earlier.

The city’s case tally makes up the vast majority of cases nationwide even as most of its 25 million residents remain under lockdown…

At the Zhengzhou economic zone, only personnel with valid passes, health codes and proof of negative Covid tests would be able to leave during the two-week period, although “special vehicles” would be able to travel normally for work reasons, local authorities said in a post on an official WeChat instant messaging account.

Overall, China reported 24,791 new coronavirus cases on 15 April, of which 3,896 were symptomatic and 20,895 were asymptomatic, the National Health Commission said on Saturday.

UN OCHA – Current Emergencies

UN OCHA – Current Emergencies
Current Corporate Emergencies
Afghanistan
No new updates identified.

 

Northern Ethiopia
Ethiopia – Northern Ethiopia Humanitarian Update Situation Report, 14 Apr 2022
HIGHLIGHTS
Humanitarian partners have not been able to move any additional aid supplies into Tigray by road since the convoy entered on 1 and 2 April.
About 36 metric tons of HIV medical supplies were airlifted to Mekelle, the first time since July 2021. It will be enough to provide treatment for 46,000 patients for six months.
Authorities in Amhara relocated more than 20,000 people out of the planned 70,000 people in North Wello and Wag Hamra zones to new designated sites since mid-March.
WFP assisted over 35,000 people with food in Gulina, Barahle and Dalole woredas in Afar during the reporting period, reaching over 235,000 people since last week of February.
More than 11,000 children under five and pregnant and lactating women received supplementary nutrients in Wag Harma and North Wello zones in Amhara between 1 and 10 April.

Ukraine
Ukraine: Humanitarian Impact Situation Report (As of 12:00 p.m. (EET) on 15 April 2022)

WHO & Regional Offices [to 16 Apr 2022]

WHO & Regional Offices [to 16 Apr 2022]
https://www.who.int/news
News [Selected]
14 April 2022
Departmental news
The Global Diabetes Compact: a promising first year

14 April 2022
Departmental news
World Chagas Disease Day: finding and reporting every case

13 April 2022
Statement
Statement on the eleventh meeting of the International Health Regulations (2005) Emergency Committee regarding the coronavirus disease (COVID-19) pandemic
[See Milestones above for detail]

13 April 2022
Departmental news
Ukraine next country to receive technology from the WHO mRNA technology transfer hub

12 April 2022
Departmental news
Meeting of WHO Director-General’s Expert Group on Cervical Cancer Elimination, 19 April 2022

11 April 2022
Departmental news
SAGE April 2022 meeting highlights
[See Milestones above for detail]

11 April 2022
Departmental news
WHO, WIPO, WTO launch trilateral COVID-19 technical assistance platform

11 April 2022
News release
One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer
[See Milestones above for detail]

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WHO Director General Speeches [selected]
https://www.who.int/director-general/speeches
Selected
14 April 2022
Speech
WHO Director-General’s opening remarks on Member State Information Session on COVID-19 – 14 April 2022

14 April 2022
Speech
WHO Director-General’s opening remarks at the Briefing to the African Union Ambassadors in Geneva on Strengthening Local Manufacturing Capacity – 14 April 2022

13 April 2022
Speech
WHO Director-General’s opening remarks at the WHO press conference – 13 April 2022

12 April 2022
Speech
WHO Director-General’s opening remarks at the International Strategic Dialogue on Noncommunicable Diseases and the Sustainable Development Goals – 12 April 2022

12 April 2022
Speech
WHO Director-General’s opening remarks at the Global Launch of the WHO QualityRights e-training to advance mental health, eliminate stigma and promote community inclusion  – 12 April 2022

12 April 2022
Speech
WHO Director-General’s opening remarks at the Public Hearing regarding a new international instrument on pandemic preparedness and response – 12 April 2022

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WHO Regional Offices
Selected Press Releases, Announcements
WHO African Region
:: Africa witnesses longest-running decline in COVID-19 cases 14 April 2022
Brazzaville – Africa is experiencing its longest-running decline in COVID-19 infections since the onset of the pandemic. Recorded weekly cases have fallen for the past 16 weeks, while deaths have dropped for the last eight.
Infections—largely due to the Omicron-driven fourth pandemic wave—have tanked from a peak of over 308 000 cases weekly at the start of the year to less than 20 000 in the week ending on 10 April 2022. Over the past week, around 18 000 cases and 239 deaths were recorded, a decline of 29% and 37% respectively compared with the week before. This low level of infection has not been seen since April 2020 in the early stages of the pandemic in Africa…
:: Botswana, South Africa deepen probe into new Omicron sub-variants 12 April 2022
Brazzaville – Researchers in Botswana and South Africa have detected new sub-lineages of the Omicron variant of the SARS-CoV-2 and are carrying out further investigations to fully understand crucial traits such as infectivity and virulence.
The identified sub-lineages variant are BA.4 and BA.5. World Health Organization (WHO) experts are working with scientists and researchers in the two countries to deepen analysis of the sub-lineages which have so far been identified in four people in Botswana and 23 in South Africa. Outside Africa, the BA.4 and the BA.5 have been confirmed in Belgium, Denmark, Germany and the United Kingdom…
:: Deaths from noncommunicable diseases on the rise in Africa 11 April 2022
Accra/Brazzaville – Noncommunicable diseases such as cancer, cardiovascular diseases and diabetes are increasingly becoming the main cause of mortality in sub-Saharan Africa, where the diseases were responsible for 37% of deaths in 2019, rising from 24% in 2000 largely due to weaknesses in the implementation of critical control measures including prevention, diagnosis and care. This comes on the eve of a high-level heads of state and health leaders meeting in Ghana to find ways of accelerating progress against noncommunicable diseases…

WHO Region of the Americas PAHO
:: 13 Apr 2022
Less than 10% of those infected with Chagas disease receive timely diagnosis and treatment
PAHO calls for detection of all cases and equitable access to care for this disease, which causes about 30,000 new infections each year. Washington, DC, April 13, 2022 (PAHO)- Due to its silent nature, less than 10% of those infected with Chagas disease each year receive timely diagnosis and, therefore, effective treatment in Mexico, Central…
:: 11 Apr 2022
One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer
Geneva, 11 April 2022 (WHO)- The 4-7 April convening of the WHO Strategic Advisory Group of Experts on Immunization (SAGE) evaluated the evidence that has been emerging over past years that single-dose schedules provide comparable efficacy to the two or three-dose regimens. SAGE’s review concluded that a single-dose Human Papillomavirus (HPV)…

WHO South-East Asia Region SEARO
No new digest content identified.

WHO European Region EURO
:: Regional Director pledges WHO support to help Ukraine’s health system build back better during visit to Lviv 13-04-2022
:: Adjusting health financing for people fleeing conflict: WHO releases new guidance for countries in Europe 13-04-2022
:: ‘Ensuring high-quality of HIV Care for displaced people from Ukraine’ 13-04-2022
:: Novo Nordisk Foundation supports WHO’s emergency response in Ukraine and neighbouring countries with 25 million Danish kroner/3.4 million euros 13-04-2022

WHO Eastern Mediterranean Region EMRO
:: Taking the battle against malaria to its source – the mosquito 14 April 2022
:: WHO and KSrelief join efforts in the fight against child malnutrition in Yemen 13 April 2022
:: WHO delivers rapid antigen tests for COVID-19 to Iraq 11 April 2022

WHO Western Pacific Region
No new digest content identified.

 

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Disease Outbreak News (DONs)
Latest WHO Disease Outbreak News (DONs), providing information on confirmed acute public health events or potential events of concern.
15 April 2022 | Circulating vaccine-derived poliovirus type 3 – Israel

 

15 April 2022 | Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland

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WHO Events
https://www.who.int/news-room/events/1
[Selected]
WHO Public Health Laboratories knowledge sharing webinars – Genomic surveillance and building up Next Generation Sequencing capacity
20 April 2022 11:00 – 12:30 CET

 

World Immunization Week
World Immunization Week 2022 – Long Life for All
24 – 30 April 2022

 

World Malaria Day 2022 – Harness innovation to reduce the malaria disease burden and save lives
25 April 2022

 

10th ACT-Accelerator Facilitation Council meeting
26 April 2022 12:30 – 15:00 CET

 

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New WHO Publications
https://www.who.int/publications/i
Selected Titles
14 April 2022
Environmental surveillance for SARS-COV-2 to complement public health surveillance – Interim Guidance
Overview
Routine diagnostic surveillance for COVID-19 has been augmented with environmental surveillance (ES) in wastewater in many locations. ES provides additional evidence on virus in circulation at population level including presence or absence, early warning of increasing or decreasing trends, and information on variants of concern or interest.
This guidance provides advice on:
What situations ES has been shown to add value to public health decision making
What is needed to plan and coordinate an effective ES programme
How to carry out data collection, analysis, interpretation and communication of results.
This guidance is targeted at public health officials who want to understand and integrate complementary ES into COVID-19 control strategies.

14 April 2022
Emergency in Ukraine: external situation report #7, published 14 April 2022: reporting period: 7–13 April…

13 April 2022
INSPIRE: seven strategies for ending violence against children: uptake between 2016 and 2021

13 April 2022
Health system performance assessment

12 April 2022
Optimized broth microdilution plate methodology for drug susceptibility testing of Mycobacterium tuberculosis…

12 April 2022
WHO Expert Committee on Biological Standardization: seventy-fourth report

12 April 2022
Emergency use of unproven clinical interventions outside clinical trials: ethical considerations
[See COVID above for detail]

12 April 2022
Ethics and medical radiological imaging: a policy brief for health-care providers

12 April 2022
Towards better engagement of the private sector in health service delivery

12 April 2022
Equitable access to COVID-19 tools
[See COVID above for detail]

11 April 2022
How to temperature map cold chain equipment and storage areas

11 April 2022
Noncommunicable Diseases Progress Monitor 2022

MMWR  Weekly: Current Volume (71) April 15, 2022 / No. 15

MMWR  Weekly: Current Volume (71) April 15, 2022 / No. 15
PDF of this issue
Surveillance to Track Progress Toward Polio Eradication — Worldwide, 2020–2021
COVID-19 Mortality and Vaccine Coverage — Hong Kong Special Administrative Region, China, January 6, 2022–March 21, 2022
Effectiveness of COVID-19 mRNA Vaccination in Preventing COVID-19–Associated Hospitalization Among Adults with Previous SARS-CoV-2 Infection — United States, June 2021–February 2022

Organization Announcements

Organization Announcements

Editor’s Note:

Careful readers will note that the number and range of organizations now monitored in our Announcements section below has grown as the impacts of the pandemic have spread across global economies, supply chains and programmatic activity of multilateral agencies and INGOs.

Airfinity    [to 16 Apr 2022]

https://www.airfinity.com/insights

INSIGHTS & COMPANY NEWS

Airfinity downgrades its global COVID-19 vaccine revenue forecast to $64.1B

Published by Airfinity

Apr 10, 2022

   Airfinity has downgraded its global sales forecast for COVID-19 vaccines this year from $80.8bn to $64.1bn.

Paul G. Allen Frontiers Group    [to 16 Apr 2022]

https://alleninstitute.org/news-press/

News

No new digest content identified.

BMGF – Gates Foundation  [to 16 Apr 2022]

https://www.gatesfoundation.org/ideas/media-center

Press Releases and Statements

No new digest content identified.

Bill & Melinda Gates Medical Research Institute    [to 16 Apr 2022]

https://www.gatesmri.org/news

The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people

No new digest content identified.

CARB-X   [to 16 Apr 2022]

News

No new digest content identified.

Center for Vaccine Ethics and Policy – GE2P2 Global Foundation   [to 16 Apr 2022]

https://centerforvaccineethicsandpolicy.net/

News/Analysis/Statements

:: Past weekly editions and posting of all segments of Vaccines and Global Health: The Week in Review are available here.

:: Informed Consent: A Monthly Review – April 2022is now posted here

:: Statement on ICF [Informed Consent Form] Posting for Clinical Trials Involving Gene Editing/Gene Therapies – Invitation to Endorse

:: Patients, Politics, Pressure :: Pharma Stays Steady [Mostly] In Russia Sanctions Context

Observations at 30 March 2022     David R Curry


CEPI – Coalition for Epidemic Preparedness Innovations  [to 16 Apr 2022]

http://cepi.net/

Latest News

No new digest content identified.

DARPA – Defense Advanced Research Projects Agency [U.S.] [to 16 Apr 2022

https://www.darpa.mil/news

News

No new digest content identified.

Duke Global Health Innovation Center  [to 16 Apr 2022]

Our Blog

No new digest content identified.

EDCTP    [to 16 Apr 2022]

http://www.edctp.org/

The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials

News

No new digest content identified.

Emory Vaccine Center    [to 16 Apr 2022]

http://www.vaccines.emory.edu/

Vaccine Center News

No new digest content identified.

European Vaccine Initiative  [to 16 Apr 2022]

http://www.euvaccine.eu/

Latest News, Events

No new digest content identified.

Evidence Aid   [to 16 Apr 2022]

Evidence Aid aims to save lives and livelihoods in disasters by providing decision-makers with the best available evidence and by championing its use.

http://www.evidenceaid.org/

New Resources

No new digest content identified.

Fondation Merieux  [to 16 Apr 2022]

http://www.fondation-merieux.org/

News, Events 

Mérieux Foundation & University of Geneva co-organized event

22nd Advanced Vaccinology Course (ADVAC)

May 9 – 20, 2022 – Les Pensières Center for Global Health, Veyrier-du-Lac (France)

Gavi [to 16 Apr 2022]

https://www.gavi.org/

News Releases

No new digest content identified.

GHIT Fund   [to 16 Apr 2022]

https://www.ghitfund.org/newsroom/press

Press Releases

No new digest content identified.

Global Fund  [to 16 Apr 2022]

https://www.theglobalfund.org/en/news/

News & Stories

No new digest content identified.

Global Research Collaboration for Infectious Disease Preparedness [GloPID-R] [to 16 Apr 2022]

News

No new digest content identified

Hilleman Laboratories   [to 16 Apr 2022]

http://www.hilleman-labs.org/

News & Insights

No new digest content identified

HHMI – Howard Hughes Medical Institute    [to 16 Apr 2022]

https://www.hhmi.org/news

Press Room                    

No new digest content identified.

Human Vaccines Project   [to 16 Apr 2022]

http://www.humanvaccinesproject.org/

News

No new digest content identified.

IAVI  [to 16 Apr 2022]

https://www.iavi.org/

Latest News

No new digest content identified.

ICRC  [to 16 Apr 2022]

https://www.icrc.org/en/whats-new

What’s New   [Selected]

Equitable access to COVID-19 vaccination is a humanitarian imperative

   Statement by the International Committee of the Red Cross (ICRC) at the United Nations Security Council, New York 11 April 2022. Delivered by Dr. Esperanza Martinez, Senior Advisor to the Office of the Director-General.

12-04-2022 | Statement

[See COVID above for detail]

International Coalition of Medicines Regulatory Authorities [ICMRA]

http://www.icmra.info/drupal/en/news

Selected Statements, Press Releases, Research

No new digest content identified.

IFFIm

http://www.iffim.org/

Press Releases/Announcements

No new digest content identified.

IFRC   [to 16 Apr 2022]

http://media.ifrc.org/ifrc/news/press-releases/

Press Releases [Selected]

14/04/2022

Tonga: Red Cross tackles triple disaster – COVID-19, volcanic fallout, tsunami

14/04/2022

IFRC to support more than 2 million people affected by the conflict in Ukraine with its largest ever

Institut Pasteur   [to 16 Apr 2022]

https://www.pasteur.fr/en/press-area

Press Documents

Press release   14.04.2022

Decoding a direct dialog between the gut microbiota and the brain

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity,…

Press release   13.04.2022

Colon cancer: how mutation of the APC gene disrupts lymphocyte migration

In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC…

Press release   12.04.2022

HIV: The Antibodies of “Post-treatment Controllers”

A very small percentage of people with HIV-1, known as “post-treatment controllers” (PTCs), are able to control their…

IOM / International Organization for Migration [to 16 Apr 2022]    

http://www.iom.int/press-room/press-releases

News – Selected

No new digest content identified.

ISC / International Science Council  [to 16 Apr 2022]

https://council.science/current/

ISC is a non-governmental organization with a unique global membership that brings together 40 international scientific Unions and Associations and over 140 national and regional scientific organizations including Academies and Research Councils.

News  Blogs  Podcasts Events

Blogs

A call to ISC Members: how to assist displaced Ukrainian scholars

11.04.2022

IVAC  [to 16 Apr 2022]

Updates; Events

World Immunization Week 2022: Webinars

April 2022

   During World Immunization Week 2022 the International Vaccine Access Center, along with global immunization and indigenous health partners, will host a three webinars. Registration is free, and we encourage all to sign up and save these dates on their calendars. Enabling Equitable Access to COVID-19 Vaccines for Indigenous Populations When: April 26, 2022 from 6:00 […]

IVI   [to 16 Apr 2022]

http://www.ivi.int/

IVI News & Announcements

No new digest content identified.

Johns Hopkins Center for Health Security   [to 16 Apr 2022]

https://www.centerforhealthsecurity.org/news/center-news/

Center News

No new digest content identified.

MSF/Médecins Sans Frontières  [to 16 Apr 2022]

http://www.msf.org/

Latest [Selected Announcements]

War in Ukraine

Finding our most useful role in our response in and around Ukraine

Project Update 11 Apr 2022

National Academy of Medicine – USA  [to 16 Apr 2022]

News

No new digest content identified.

National Academy of Sciences – USA  [to 16 Apr 2022]

http://www.nasonline.org/news-and-multimedia/

News

No new digest content identified.

National Vaccine Program Office – U.S. HHS  [to 16 Apr 2022]

https://www.hhs.gov/vaccines/about/index.html

Upcoming Meetings/Latest Updates                          

No new digest content identified.

NIH  [to 16 Apr 2022]

http://www.nih.gov/

News Releases 

[Website not responding at inquiry]

OECD  [to 16 Apr 2022]

http://www.oecd.org/newsroom/publicationsdocuments/bydate/

Newsroom/Library

COVID-19 assistance to developing countries lifts foreign aid in 2021 – OECD

   Foreign aid from official donors rose to an all-time high of USD 179 billion in 2021, up 4.4% in real terms from 2020 as developed countries stepped up their help for developing countries grappling with the COVID-19 crisis, according to preliminary data collected by the OECD.

PATH  [to 16 Apr 2022]                                      

https://www.path.org/media-center/

Press Releases

No new digest content identified.

Sabin Vaccine Institute  [to 16 Apr 2022]

http://www.sabin.org/updates/pressreleases

Statements and Press Releases

No new digest content identified.

UNAIDS [to 16 Apr 2022]

http://www.unaids.org/en

Selected Press Releases/Reports/Statements

14 April 2022

Life-saving logistics in Ukraine

UNHCR Office of the United Nations High Commissioner for Refugees [to 16 Apr 2022]

http://www.unhcr.org/en-us/media-centre.htmlS

Selected News Releases, Announcements

UN Refugee Agency opposes UK plan to export asylum

14 Apr 2022

Spiraling costs, surging conflict, and soaring climate disasters create a desperate future for millions of refugees across Eastern Africa

WFP and UNHCR Joint News Release

13 Apr 2022

Statement on risks of trafficking and exploitation facing refugees from Ukraine attributed to UNHCR’s Assistant High Commissioner for Protection

The following statement is attributed to Gillian Triggs, UNHCR’s Assistant High Commissioner for Protection

12 Apr 2022

UNICEF  [to 16 Apr 2022]

https://www.unicef.org/media/press-releases

Press Releases, News Notes, Statements  [Selected]

Remarks

04/12/2022

“We must take the rapid action needed to accelerate vaccination.”

https://www.unicef.org/press-releases/we-must-take-rapid-action-needed-accelerate-vaccination

[See COVID above for detail]

Unitaid  [to 16 Apr 2022]

Featured News

13 April 2022

World Chagas Day: Unitaid remains committed to improving access to testing and treatment to reduce mother-to-child transmission of Chagas  

   … Unitaid’s efforts, underway in Brazil, Bolivia, Colombia and Paraguay, seek to demonstrate new approaches to testing, treatment and care for Chagas disease that will generate valuable evidence to facilitate the adoption of feasible and cost-effective health strategies for combatting Chagas disease across the region and globally…

Vaccine Equity Cooperative [nee Initiative]   [to 16 Apr 2022]

News

No new digest content identified.

Vaccination Acceptance & Demand Initiative [Sabin)  [to 16 Apr 2022]

https://www.vaccineacceptance.org/

Announcements, Blog

No new digest content identified.

Vaccine Confidence Project  [to 16 Apr 2022]

http://www.vaccineconfidence.org/

News, Research and Reports

No new digest content identified.

Vaccine Education Center – Children’s Hospital of Philadelphia  [to 16 Apr 2022]

http://www.chop.edu/centers-programs/vaccine-education-center

News

No new digest content identified.

Wellcome Trust  [to 16 Apr 2022]

https://wellcome.ac.uk/news

News. Opinion, Reports

No new digest content identified.

The Wistar Institute   [to 16 Apr 2022]

https://www.wistar.org/news/press-releases

Press Releases

No new digest content identified.

WFPHA: World Federation of Public Health Associations  [to 16 Apr 2022]

Latest News – Blog

No new digest content identified.

World Bank [to 16 Apr 2022]

http://www.worldbank.org/en/news/all

Selected News, Announcements

Green Fiscal Reforms can Protect Vulnerable Households and Boost COVID-19 Recovery Efforts in Europe

BRUSSELS, April 14, 2022 – Green fiscal reforms can help protect vulnerable households and support pandemic recovery efforts in European countries on the road to climate neutrality by 2050, says a new…

Date: April 14, 2022 Type: Press Release

Joint Statement: The Heads of the World Bank Group, IMF, WFP, and WTO Call for Urgent Coordinated Action on Food Security

 Proposed actions to help vulnerable countries include providing emergency food supplies and deploying financial support to households and countries; facilitating unhindered trade; investing in sustainable…

Date: April 13, 2022 Type: Press Release

Joint Statement: The Heads of the World Bank Group, IMF, WFP, and WTO Call for Urgent Coordinated Action on Food Security

Proposed actions to help vulnerable countries include providing emergency food supplies and deploying financial support to households and countries; facilitating unhindered trade; investing in sustainable…

Date: April 13, 2022 Type: Statement

World Customs Organization – WCO  [to 16 Apr 2022]

http://www.wcoomd.org/

Latest News

No new digest content identified.

World Organisation for Animal Health (OIE)   [to 16 Apr 2022]

https://www.oie.int/en/media/news/

Press Releases, Statements

No new digest content identified.

WTO – World Trade Organisation [to 16 Apr 2022]

http://www.wto.org/english/news_e/news_e.htm

WTO News and Events [Selected]

World Bank, IMF, WFP and WTO call for urgent coordinated action on food security

13 April 2022

The heads of the World Bank, the International Monetary Fund (IMF), the United Nations World Food Program (WFP) and the WTO issued a joint statement on 13 April urging coordinated action to help vulnerable countries address growing threats to food security. The proposed actions include providing emergency food supplies and deploying financial support to households and countries, facilitating unhindered trade, and investing in sustainable food production and nutrition security.

WHO, WIPO, WTO launch trilateral COVID-19 technical assistance platform

11 April 2022

The World Health Organization (WHO), the World Intellectual Property Organization (WIPO) and the WTO launched on 11 April 2022 their new Trilateral COVID-19 Technical Assistance Platform. This new tool aims to help members and WTO accession candidates address their capacity building needs to respond to the COVID-19 pandemic.

[See COVID above for detail]

::::::

ARM [Alliance for Regenerative Medicine]  [to 16 Apr 2022]

Selected Press Releases

No new digest content identified.

BIO    [to 16 Apr 2022]

https://www.bio.org/press-releases

Press Releases, Letters, Testimony, Comments [Selected]

No new digest content identified.

DCVMN – Developing Country Vaccine Manufacturers Network  [to 16 Apr 2022]

http://www.dcvmn.org/

News; Upcoming events

No new digest content identified.

ICBA – International Council of Biotechnology Associations   [to 16 Apr 2022]

https://internationalbiotech.org/news/

News

No new digest content identified.

IFPMA   [to 16 Apr 2022]

http://www.ifpma.org/resources/news-releases/

Selected Press Releases, Statements, Publications

COVID-19 vaccines and treatments output continues apace; as health systems and last mile hurdles remain

13 April 2022

[See COVID above for detail]

IFPMA statement at public hearings regarding a new international instrument on pandemic preparedness and response

13 April 2022

   The biopharmaceutical industry is committed to working with stakeholders to improve pandemic preparedness for the future and to ensure equitable access to medical countermeasures.

   Any system should be built on what worked well during the COVID-19 pandemic with robust IP frameworks enabling collaborations, as well as immediate sharing of pathogens.

   As the INB enters deeper discussions on a new instrument we believe these should be informed by a few core principles:

International Generic and Biosimilar Medicines Association [IGBA]

https://www.igbamedicines.org/

News

No new digest content identified.

International Alliance of Patients’ Organizations – IAPO  [to 16 Apr 2022]

https://www.iapo.org.uk/news/topic/6

Press and media [Selected]

No new digest content identified.

PhRMA    [to 16 Apr 2022]

http://www.phrma.org/

Latest News [Selected]

No new digest content identified.

Journal Watch

Journal Watch
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org

Health Equity in US Latinx Communities

AMA Journal of Ethics
Volume 24, Number 4: E249-341 Apr 2022
https://journalofethics.ama-assn.org/issue/health-equity-us-latinx-communities

 

Health Equity in US Latinx Communities
Latinx communities in the US include over 60 million people with a plurality of political beliefs, cultural practices, and wealth. This diversity is also expressed in population health data: some health indicators suggest advantages of Latinx community membership while other data demonstrate inequitable disease burden and maldistribution of environmental and occupational risk. Legacies of colonial conquest of the Americas persist in discrimination and marginalization today and are embodied by members of our Latinx communities.

Studying SARS-CoV-2 vaccine hesitancy among health professionals in Tunisia

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content

 

(Accessed 16 Apr 2022)
Studying SARS-CoV-2 vaccine hesitancy among health professionals in Tunisia
People’s lives were seriously affected by the emergence and the spread of the COVID-19 disease. Several vaccines were developed in record time to overcome this pandemic. However, putting an end to this public …
Authors: Nawel Zammit, Amani El Gueder, Aïcha Brahem, Imen Ayouni, Rim Ghammam, Sihem Ben Fredj, Chaima Sridi, Asma Chouchene, Houda Kalboussi, Olfa El Maalel, Souhaeil Chatti, Jihene Maatoug, Hassen Ghannem and Néjib Mrizak
Citation: BMC Health Services Research 2022 22:489
Content type: Research Published on: 12 April 2022

Children with SARS-CoV-2 infection during the novel coronaviral disease (COVID-19) outbreak in Iran: an alarming concern for severity and mortality of the disease

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 16 Apr 2022)

 

Children with SARS-CoV-2 infection during the novel coronaviral disease (COVID-19) outbreak in Iran: an alarming concern for severity and mortality of the disease
The rapid worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections led to public health crises globally and the number of pediatric patients with Coronavirus Disease 2019 (CO…
Authors: Setareh Mamishi, Babak Pourakbari, Mehrzad Mehdizadeh, Amene Navaeian, Hamid Eshaghi, Bahareh Yaghmaei, Reihaneh Hosseinpour Sadeghi, Shiva Poormohammadi, Yasmine Mahmoudieh and Shima Mahmoudi
Citation: BMC Infectious Diseases 2022 22:382
Content type: Research article Published on: 15 April 2022

Determinants of measles vaccination dropout among 12 − 23 months aged children in pastoralist community of Afar, Ethiopia

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 16 Apr 2022)

 

Determinants of measles vaccination dropout among 12 − 23 months aged children in pastoralist community of Afar, Ethiopia
Measles is a viral disease and a leading vaccine-preventable childhood killer. More than 95% of measles deaths occur in countries with low incomes and weak health infrastructures. In response to this, Ethiopia…
Authors: Chekole Hailu, Girmatsion Fisseha and Aregawi Gebreyesus
Citation: BMC Infectious Diseases 2022 22:376
Content type: Research article Published on: 14 April 2022

Barriers to and strategies to address COVID-19 testing hesitancy: a rapid scoping review

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 16 Apr 2022)

 

Barriers to and strategies to address COVID-19 testing hesitancy: a rapid scoping review
Testing is a foundational component of any COVID-19 management strategy; however, emerging evidence suggests that barriers and hesitancy to COVID-19 testing may affect uptake or participation and often these a…
Authors: Mark Embrett, S. Meaghan Sim, Hilary A. T. Caldwell, Leah Boulos, Ziwa Yu, Gina Agarwal, Rhiannon Cooper, Allyson J. Gallant AJ, Iwona A. Bielska, Jawad Chishtie, Kathryn Stone, Janet Curran and Andrea Tricco
Citation: BMC Public Health 2022 22:750
Content type: Research Published on: 14 April 2022

Considering social inequalities in health in large-scale testing for COVID-19 in Montréal: a qualitative case study

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 16 Apr 2022)

 

Considering social inequalities in health in large-scale testing for COVID-19 in Montréal: a qualitative case study
Evidence continues to demonstrate that certain marginalised populations are disproportionately affected by COVID-19. While many studies document the impacts of COVID-19 on social inequalities in health, none h…
Authors: Marie-Catherine Gagnon-Dufresne, Lara Gautier, Camille Beaujoin, Ashley Savard Lamothe, Rachel Mikanagu, Patrick Cloos, Valéry Ridde and Kate Zinszer
Citation: BMC Public Health 2022 22:749
Content type: Research Published on: 14 April 2022

Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 16 Apr 2022)

 

Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar
While mass COVID-19 vaccination programs are underway in high-income countries, limited availability of doses has resulted in few vaccines administered in low and middle income countries (LMICs). The COVID-19 …
Authors: Fidisoa Rasambainarivo, Tanjona Ramiadantsoa, Antso Raherinandrasana, Santatra Randrianarisoa, Benjamin L. Rice, Michelle V. Evans, Benjamin Roche, Fidiniaina Mamy Randriatsarafara, Amy Wesolowski and Jessica C. Metcalf
Citation: BMC Public Health 2022 22:724
Content type: Research Published on: 12 April 2022

A network of change: united action on research integrity

BMC Research Notes
http://www.biomedcentral.com/bmcresnotes/content
(Accessed 16 Apr 2022)

 

A network of change: united action on research integrity
Authors: Thomas Rhys Evans, Madeleine Pownall, Elizabeth Collins, Emma L. Henderson, Jade S. Pickering, Aoife O’Mahony, Mirela Zaneva, Matt Jaquiery and Tsvetomira Dumbalska
Citation: BMC Research Notes 2022 15:141
Content type: Commentary Published on: 14 April 2022
Abstract
The last decade has seen renewed concern within the scientific community over the reproducibility and transparency of research findings. This paper outlines some of the various responsibilities of stakeholders in addressing the systemic issues that contribute to this concern. In particular, this paper asserts that a united, joined-up approach is needed, in which all stakeholders, including researchers, universities, funders, publishers, and governments, work together to set standards of research integrity and engender scientific progress and innovation. Using two developments as examples: the adoption of Registered Reports as a discrete initiative, and the use of open data as an ongoing norm change, we discuss the importance of collaboration across stakeholders.

Learning lessons from lipids to make COVID-19 vaccines

Cell
Apr 14, 2022 Volume 185 Issue 8 p1261-1444
https://www.cell.com/cell/current

 

Conversations
Learning lessons from lipids to make COVID-19 vaccines
A game-changing intervention in the COVID-19 pandemic has been the rapid implementation of highly effective vaccines against SARS-CoV-2. The 2022 Canada Gairdner International Award recognizes Pieter Cullis, Katalin Karikó, and Drew Weissman “for their pioneering work developing nucleoside-modified mRNA and lipid nanoparticle (LNP) drug delivery: the foundational technologies for the highly effective COVID-19 mRNA vaccines.” Cell editor Cheri Sirois caught up with Pieter to discuss how a long interest in basic and applied questions in lipid biology led to this fortuitous collaboration. Excerpts of the conversation are presented below.

The voices of Ukrainian and Russian scientists

Cell
Apr 14, 2022 Volume 185 Issue 8 p1261-1444
https://www.cell.com/cell/current

 

Voices
The voices of Ukrainian and Russian scientists
Rostyslav Stoika, Nikita Gudimchuk, Halyna R. Shcherbata, Andrey Zaraisky, Oleksandr Shcheglovitov,
Yevgenia Kozorovitskiy, Viktor Korolchuk
The brutal attack on Ukraine by the Russian Federation has shocked the world. While the world works to end the violence and help refugees, as a scientific journal, our thoughts are also with those in the scientific community who are directly or indirectly impacted by the war. We have been inspired by and applaud the labs around the world that have opened their doors to displaced scientists and remain committed to supporting scientists, whoever and wherever they are. Because science requires collaboration and trust, we urge the scientific community to continue efforts like this and to remain united, especially in times as difficult as these. In this Voices piece, we feature short comments from scientists from Ukraine and scientists from Russia. This small sampling is far from exhaustive, but our sincere thanks go to those scientists who were willing to share their thoughts on this volatile and emotionally charged situation; the views expressed are those of the contributors alone. We join the world in hoping for a swift resolution to the conflict, for the good of humanity.

Therapeutic Innovations in Neuroscience

Clinical Pharmacology & Therapeutics
Volume 111, Issue 4 Pages: 705-971 April 2022
https://ascpt.onlinelibrary.wiley.com/toc/15326535/current

 

Therapeutic Innovations in Neuroscience
The theme of this issue of Clinical Pharmacology & Therapeutics (CPT) encompasses neuroscience in the broad sense to include neurology and psychiatry, nonclinical and clinical aspects, novel clinical trial methodologies, and modeling and simulation approaches applicable to central nervous system (CNS) drug development and therapy. While naturally the last two years have been dominated by coronavirus disease 2019 (COVID-19), it is important not to forget that drug development for other indications has not been stopped, albeit many trials were affected in terms of delays in recruitment and collection of clinical data.

What is the impact of intellectual property rules on access to medicines? A systematic review

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 16 Apr 2022]

 

What is the impact of intellectual property rules on access to medicines? A systematic review
It is widely accepted that intellectual property legal requirements such as patents and data exclusivity can affect access to medicines, but to date there has not been a comprehensive review of the empirical e…
Authors: Brigitte Tenni, Hazel V. J. Moir, Belinda Townsend, Burcu Kilic, Anne-Maree Farrell, Tessa Keegel and Deborah Gleeson
Citation: Globalization and Health 2022 18:40
Content type: Review Published on: 15 April 2022

Waning Immunity After Receipt of Pertussis, Diphtheria, Tetanus, and Polio-Related Vaccines: A Systematic Review and Meta-analysisGet access

Journal of Infectious Diseases
Volume 225, Issue 4, 15 February 2022
https://academic.oup.com/jid/issue/225/4

 

REVIEW
Waning Immunity After Receipt of Pertussis, Diphtheria, Tetanus, and Polio-Related Vaccines: A Systematic Review and Meta-analysisGet access
Huizhi Gao, Eric H Y Lau, Benjamin J Cowling
The Journal of Infectious Diseases, Volume 225, Issue 4, 15 February 2022, Pages 557–566, https://doi.org/10.1093/infdis/jiab480
Our results supported the notion that secondary vaccine failure may be the reason for reemergence of pertussis and diphtheria. Tetanus and polio vaccines provided more sustained protection.

COVID-19 Vaccination Rates in a Global HIV Cohort

Journal of Infectious Diseases
Volume 225, Issue 4, 15 February 2022
https://academic.oup.com/jid/issue/225/4

 

MAJOR ARTICLES AND BRIEF REPORTS
COVID-19 Vaccination Rates in a Global HIV Cohort
Evelynne S Fulda, Kathleen V Fitch, Edgar T Overton, Markella V Zanni, Judith A Aberg
The Journal of Infectious Diseases, Volume 225, Issue 4, 15 February 2022, Pages 603–607, https://doi.org/10.1093/infdis/jiab575

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021

The Lancet
Apr 16, 2022 Volume 399 Number 10334 p1441-1572, e37
https://www.thelancet.com/journals/lancet/issue/current

 

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021
COVID-19 National Preparedness Collaborators
Open Access

A joint NCBI and EMBL-EBI transcript set for clinical genomics and research

Nature
Volume 604 Issue 7905, 14 April 2022
https://www.nature.com/nature/volumes/604/issues/7905

 

Analysis | 06 April 2022 | Open Access
A joint NCBI and EMBL-EBI transcript set for clinical genomics and research
Matched Annotation from NCBI and EMBL-EBI (MANE) delivers joint transcript sets from Ensembl/GENCODE and RefSeq for standardizing variant reporting in clinical genomics and research.
Joannella Morales, Shashikant Pujar, Terence D. Murphy

Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects

Nature Genetics
Volume 54 Issue 4, April 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Article | 11 April 2022
Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects
GWASs based on self-reported phenotypes in 736,723 individuals show distinct associations between risk loci and eight COVID-19 outcomes, suggesting differences in genetic susceptibility to infection upon exposure and severe and symptomatic disease.
Genevieve H. L. Roberts, Raghavendran Partha, Kristin A. Rand

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

Nature Genetics
Volume 54 Issue 4, April 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Analysis | 28 March 2022 | Open Access
Global landscape of SARS-CoV-2 genomic surveillance and data sharing
Analyses on the global diversity of SARS-CoV-2 genomic surveillance across 118 countries and the extent of public availability of genomic data provide evidence to better inform SARS-CoV-2 surveillance policy.
Zhiyuan Chen, Andrew S. Azman, Hongjie Yu

Biosecurity in an age of open science

PLoS Biology
https://journals.plos.org/plosbiology/
(Accessed 16 Apr 2022)

 

Biosecurity in an age of open science
James Andrew Smith, Jonas B. Sandbrink
Essay | published 14 Apr 2022 PLOS Biology
https://doi.org/10.1371/journal.pbio.3001600
Abstract
The risk of accidental or deliberate misuse of biological research is increasing as biotechnology advances. As open science becomes widespread, we must consider its impact on those risks and develop solutions that ensure security while facilitating scientific progress. Here, we examine the interaction between open science practices and biosecurity and biosafety to identify risks and opportunities for risk mitigation. Increasing the availability of computational tools, datasets, and protocols could increase risks from research with misuse potential. For instance, in the context of viral engineering, open code, data, and materials may increase the risk of release of enhanced pathogens. For this dangerous subset of research, both open science and biosecurity goals may be achieved by using access-controlled repositories or application programming interfaces. While preprints accelerate dissemination of findings, their increased use could challenge strategies for risk mitigation at the publication stage. This highlights the importance of oversight earlier in the research lifecycle. Preregistration of research, a practice promoted by the open science community, provides an opportunity for achieving biosecurity risk assessment at the conception of research. Open science and biosecurity experts have an important role to play in enabling responsible research with maximal societal benefit.

A scholarly network of AI research with an information science focus: Global North and Global South perspectives

PLoS One
http://www.plosone.org/
[Accessed 16 Apr 2022]

 

Research Article
A scholarly network of AI research with an information science focus: Global North and Global South perspectives
Kai-Yu Tang, Chun-Hua Hsiao, Gwo-Jen Hwang
Research Article | published 15 Apr 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0266565