Author Archives: davidrcurry

Studying SARS-CoV-2 vaccine hesitancy among health professionals in Tunisia

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BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content

 

(Accessed 23 Apr 2022)
Studying SARS-CoV-2 vaccine hesitancy among health professionals in Tunisia
People’s lives were seriously affected by the emergence and the spread of the COVID-19 disease. Several vaccines were developed in record time to overcome this pandemic. However, putting an end to this public …
Authors: Nawel Zammit, Amani El Gueder, Aïcha Brahem, Imen Ayouni, Rim Ghammam, Sihem Ben Fredj, Chaima Sridi, Asma Chouchene, Houda Kalboussi, Olfa El Maalel, Souhaeil Chatti, Jihene Maatoug, Hassen Ghannem and Néjib Mrizak
Citation: BMC Health Services Research 2022 22:489
Content type: Research Published on: 12 April 2022

Children with SARS-CoV-2 infection during the novel coronaviral disease (COVID-19) outbreak in Iran: an alarming concern for severity and mortality of the disease

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BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 23 Apr 2022)

 

Children with SARS-CoV-2 infection during the novel coronaviral disease (COVID-19) outbreak in Iran: an alarming concern for severity and mortality of the disease
The rapid worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections led to public health crises globally and the number of pediatric patients with Coronavirus Disease 2019 (CO…
Authors: Setareh Mamishi, Babak Pourakbari, Mehrzad Mehdizadeh, Amene Navaeian, Hamid Eshaghi, Bahareh Yaghmaei, Reihaneh Hosseinpour Sadeghi, Shiva Poormohammadi, Yasmine Mahmoudieh and Shima Mahmoudi
Citation: BMC Infectious Diseases 2022 22:382
Content type: Research article Published on: 15 April 2022

Determinants of measles vaccination dropout among 12 − 23  months aged children in pastoralist community of Afar, Ethiopia

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BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 23 Apr 2022)

 

Determinants of measles vaccination dropout among 12 − 23 months aged children in pastoralist community of Afar, Ethiopia
Measles is a viral disease and a leading vaccine-preventable childhood killer. More than 95% of measles deaths occur in countries with low incomes and weak health infrastructures. In response to this, Ethiopia…
Authors: Chekole Hailu, Girmatsion Fisseha and Aregawi Gebreyesus
Citation: BMC Infectious Diseases 2022 22:376
Content type: Research article Published on: 14 April 2022

Barriers to and strategies to address COVID-19 testing hesitancy: a rapid scoping review

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BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 23 Apr 2022)

 

Barriers to and strategies to address COVID-19 testing hesitancy: a rapid scoping review
Testing is a foundational component of any COVID-19 management strategy; however, emerging evidence suggests that barriers and hesitancy to COVID-19 testing may affect uptake or participation and often these a…
Authors: Mark Embrett, S. Meaghan Sim, Hilary A. T. Caldwell, Leah Boulos, Ziwa Yu, Gina Agarwal, Rhiannon Cooper, Allyson J. Gallant AJ, Iwona A. Bielska, Jawad Chishtie, Kathryn Stone, Janet Curran and Andrea Tricco
Citation: BMC Public Health 2022 22:750
Content type: Research Published on: 14 April 2022

Considering social inequalities in health in large-scale testing for COVID-19 in Montréal: a qualitative case study

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BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 23 Apr 2022)

 

Considering social inequalities in health in large-scale testing for COVID-19 in Montréal: a qualitative case study
Evidence continues to demonstrate that certain marginalised populations are disproportionately affected by COVID-19. While many studies document the impacts of COVID-19 on social inequalities in health, none h…
Authors: Marie-Catherine Gagnon-Dufresne, Lara Gautier, Camille Beaujoin, Ashley Savard Lamothe, Rachel Mikanagu, Patrick Cloos, Valéry Ridde and Kate Zinszer
Citation: BMC Public Health 2022 22:749
Content type: Research Published on: 14 April 2022

Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar

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BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 23 Apr 2022)

 

Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar
While mass COVID-19 vaccination programs are underway in high-income countries, limited availability of doses has resulted in few vaccines administered in low and middle income countries (LMICs). The COVID-19 …
Authors: Fidisoa Rasambainarivo, Tanjona Ramiadantsoa, Antso Raherinandrasana, Santatra Randrianarisoa, Benjamin L. Rice, Michelle V. Evans, Benjamin Roche, Fidiniaina Mamy Randriatsarafara, Amy Wesolowski and Jessica C. Metcalf
Citation: BMC Public Health 2022 22:724
Content type: Research Published on: 12 April 2022

A network of change: united action on research integrity

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BMC Research Notes
http://www.biomedcentral.com/bmcresnotes/content
(Accessed 23 Apr 2022)

 

A network of change: united action on research integrity
Authors: Thomas Rhys Evans, Madeleine Pownall, Elizabeth Collins, Emma L. Henderson, Jade S. Pickering, Aoife O’Mahony, Mirela Zaneva, Matt Jaquiery and Tsvetomira Dumbalska
Citation: BMC Research Notes 2022 15:141
Content type: Commentary Published on: 14 April 2022
Abstract
The last decade has seen renewed concern within the scientific community over the reproducibility and transparency of research findings. This paper outlines some of the various responsibilities of stakeholders in addressing the systemic issues that contribute to this concern. In particular, this paper asserts that a united, joined-up approach is needed, in which all stakeholders, including researchers, universities, funders, publishers, and governments, work together to set standards of research integrity and engender scientific progress and innovation. Using two developments as examples: the adoption of Registered Reports as a discrete initiative, and the use of open data as an ongoing norm change, we discuss the importance of collaboration across stakeholders.

Learning lessons from lipids to make COVID-19 vaccines

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Cell
Apr 14, 2022 Volume 185 Issue 8 p1261-1444
https://www.cell.com/cell/current

 

Conversations
Learning lessons from lipids to make COVID-19 vaccines
A game-changing intervention in the COVID-19 pandemic has been the rapid implementation of highly effective vaccines against SARS-CoV-2. The 2022 Canada Gairdner International Award recognizes Pieter Cullis, Katalin Karikó, and Drew Weissman “for their pioneering work developing nucleoside-modified mRNA and lipid nanoparticle (LNP) drug delivery: the foundational technologies for the highly effective COVID-19 mRNA vaccines.” Cell editor Cheri Sirois caught up with Pieter to discuss how a long interest in basic and applied questions in lipid biology led to this fortuitous collaboration. Excerpts of the conversation are presented below.

The voices of Ukrainian and Russian scientists

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Cell
Apr 14, 2022 Volume 185 Issue 8 p1261-1444
https://www.cell.com/cell/current

 

Voices
The voices of Ukrainian and Russian scientists
Rostyslav Stoika, Nikita Gudimchuk, Halyna R. Shcherbata, Andrey Zaraisky, Oleksandr Shcheglovitov,
Yevgenia Kozorovitskiy, Viktor Korolchuk
The brutal attack on Ukraine by the Russian Federation has shocked the world. While the world works to end the violence and help refugees, as a scientific journal, our thoughts are also with those in the scientific community who are directly or indirectly impacted by the war. We have been inspired by and applaud the labs around the world that have opened their doors to displaced scientists and remain committed to supporting scientists, whoever and wherever they are. Because science requires collaboration and trust, we urge the scientific community to continue efforts like this and to remain united, especially in times as difficult as these. In this Voices piece, we feature short comments from scientists from Ukraine and scientists from Russia. This small sampling is far from exhaustive, but our sincere thanks go to those scientists who were willing to share their thoughts on this volatile and emotionally charged situation; the views expressed are those of the contributors alone. We join the world in hoping for a swift resolution to the conflict, for the good of humanity.

Therapeutic Innovations in Neuroscience

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Clinical Pharmacology & Therapeutics
Volume 111, Issue 4 Pages: 705-971 April 2022
https://ascpt.onlinelibrary.wiley.com/toc/15326535/current

 

Therapeutic Innovations in Neuroscience
The theme of this issue of Clinical Pharmacology & Therapeutics (CPT) encompasses neuroscience in the broad sense to include neurology and psychiatry, nonclinical and clinical aspects, novel clinical trial methodologies, and modeling and simulation approaches applicable to central nervous system (CNS) drug development and therapy. While naturally the last two years have been dominated by coronavirus disease 2019 (COVID-19), it is important not to forget that drug development for other indications has not been stopped, albeit many trials were affected in terms of delays in recruitment and collection of clinical data.

What is the impact of intellectual property rules on access to medicines? A systematic review

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Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 23 Apr 2022]

 

What is the impact of intellectual property rules on access to medicines? A systematic review
It is widely accepted that intellectual property legal requirements such as patents and data exclusivity can affect access to medicines, but to date there has not been a comprehensive review of the empirical e…
Authors: Brigitte Tenni, Hazel V. J. Moir, Belinda Townsend, Burcu Kilic, Anne-Maree Farrell, Tessa Keegel and Deborah Gleeson
Citation: Globalization and Health 2022 18:40
Content type: Review Published on: 15 April 2022

Waning Immunity After Receipt of Pertussis, Diphtheria, Tetanus, and Polio-Related Vaccines: A Systematic Review and Meta-analysis

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Journal of Infectious Diseases
Volume 225, Issue 4, 15 February 2022
https://academic.oup.com/jid/issue/225/4

 

REVIEW
Waning Immunity After Receipt of Pertussis, Diphtheria, Tetanus, and Polio-Related Vaccines: A Systematic Review and Meta-analysisGet access
Huizhi Gao, Eric H Y Lau, Benjamin J Cowling
The Journal of Infectious Diseases, Volume 225, Issue 4, 15 February 2022, Pages 557–566, https://doi.org/10.1093/infdis/jiab480
Our results supported the notion that secondary vaccine failure may be the reason for reemergence of pertussis and diphtheria. Tetanus and polio vaccines provided more sustained protection.

COVID-19 Vaccination Rates in a Global HIV Cohort

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Journal of Infectious Diseases
Volume 225, Issue 4, 15 February 2022
https://academic.oup.com/jid/issue/225/4

 

MAJOR ARTICLES AND BRIEF REPORTS
COVID-19 Vaccination Rates in a Global HIV Cohort
Evelynne S Fulda, Kathleen V Fitch, Edgar T Overton, Markella V Zanni, Judith A Aberg …
The Journal of Infectious Diseases, Volume 225, Issue 4, 15 February 2022, Pages 603–607, https://doi.org/10.1093/infdis/jiab575

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021

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The Lancet
Apr 16, 2022 Volume 399 Number 10334 p1441-1572, e37
https://www.thelancet.com/journals/lancet/issue/current

 

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021
COVID-19 National Preparedness Collaborators
Open Access

A joint NCBI and EMBL-EBI transcript set for clinical genomics and research

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Nature
Volume 604 Issue 7905, 14 April 2022
https://www.nature.com/nature/volumes/604/issues/7905

 

Analysis | 06 April 2022 | Open Access
A joint NCBI and EMBL-EBI transcript set for clinical genomics and research
Matched Annotation from NCBI and EMBL-EBI (MANE) delivers joint transcript sets from Ensembl/GENCODE and RefSeq for standardizing variant reporting in clinical genomics and research.
Joannella Morales, Shashikant Pujar, Terence D. Murphy

Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects

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Nature Genetics
Volume 54 Issue 4, April 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Article | 11 April 2022
Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects
GWASs based on self-reported phenotypes in 736,723 individuals show distinct associations between risk loci and eight COVID-19 outcomes, suggesting differences in genetic susceptibility to infection upon exposure and severe and symptomatic disease.
Genevieve H. L. Roberts, Raghavendran Partha, Kristin A. Rand

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

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Nature Genetics
Volume 54 Issue 4, April 2022
https://www.nature.com/ng/volumes/54/issues/4

 

Analysis | 28 March 2022 | Open Access
Global landscape of SARS-CoV-2 genomic surveillance and data sharing
Analyses on the global diversity of SARS-CoV-2 genomic surveillance across 118 countries and the extent of public availability of genomic data provide evidence to better inform SARS-CoV-2 surveillance policy.
Zhiyuan Chen, Andrew S. Azman, Hongjie Yu

Biosecurity in an age of open science

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PLoS Biology
https://journals.plos.org/plosbiology/
(Accessed 23 Apr 2022)

 

Biosecurity in an age of open science
James Andrew Smith, Jonas B. Sandbrink
Essay | published 14 Apr 2022 PLOS Biology
https://doi.org/10.1371/journal.pbio.3001600
Abstract
The risk of accidental or deliberate misuse of biological research is increasing as biotechnology advances. As open science becomes widespread, we must consider its impact on those risks and develop solutions that ensure security while facilitating scientific progress. Here, we examine the interaction between open science practices and biosecurity and biosafety to identify risks and opportunities for risk mitigation. Increasing the availability of computational tools, datasets, and protocols could increase risks from research with misuse potential. For instance, in the context of viral engineering, open code, data, and materials may increase the risk of release of enhanced pathogens. For this dangerous subset of research, both open science and biosecurity goals may be achieved by using access-controlled repositories or application programming interfaces. While preprints accelerate dissemination of findings, their increased use could challenge strategies for risk mitigation at the publication stage. This highlights the importance of oversight earlier in the research lifecycle. Preregistration of research, a practice promoted by the open science community, provides an opportunity for achieving biosecurity risk assessment at the conception of research. Open science and biosecurity experts have an important role to play in enabling responsible research with maximal societal benefit.

A scholarly network of AI research with an information science focus: Global North and Global South perspectives

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PLoS One
http://www.plosone.org/
[Accessed 23 Apr 2022]

 

Research Article
A scholarly network of AI research with an information science focus: Global North and Global South perspectives
Kai-Yu Tang, Chun-Hua Hsiao, Gwo-Jen Hwang
Research Article | published 15 Apr 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0266565

Acceptance of COVID-19 Vaccine Among High-Risk Occupations in a Port City of China and Multifaceted Strategies for Increasing Vaccination Coverage: A Cross-Sectional Study

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Risk Management and Healthcare Policy
https://www.dovepress.com/risk-management-and-healthcare-policy-archive56
[Accessed 23 Apr 2022]

 

Original Research
Acceptance of COVID-19 Vaccine Among High-Risk Occupations in a Port City of China and Multifaceted Strategies for Increasing Vaccination Coverage: A Cross-Sectional Study
Sun Y, Li B, Li N, Li B, Chen P, Hao F, Sun C
Risk Management and Healthcare Policy 2022, 15:643-655
Published Date: 14 April 2022

Long-term effectiveness of human papillomavirus vaccines among adult women: A real-world scenario

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Open access
Long-term effectiveness of human papillomavirus vaccines among adult women: A real-world scenario
Ga Young Lee, Perapong Inthasorn, Piyawat Laowahutanont, Saranath Lawpoolsri, … Punnee Pitisuttithum
Pages 1968-1976

Promoting immunization equity in Latin America and the Caribbean: Case studies, lessons learned, and their implication for COVID-19 vaccine equity

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Full text access
Promoting immunization equity in Latin America and the Caribbean: Case studies, lessons learned, and their implication for COVID-19 vaccine equity
Isabella L. Chan, Robin Mowson, Juan Pedro Alonso, Javier Roberti, … Martha Velandia-González

Impact of the Sinopharm’s BBIBP-CorV vaccine in preventing hospital admissions and death in infected vaccinees: Results from a retrospective study in the emirate of Abu Dhabi, United Arab Emirates (UAE)

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Open access
Impact of the Sinopharm’s BBIBP-CorV vaccine in preventing hospital admissions and death in infected vaccinees: Results from a retrospective study in the emirate of Abu Dhabi, United Arab Emirates (UAE)
Farida Ismail AlHosani, Anderson Eduardo Stanciole, Bashir Aden, Andrey Timoshkin, … Farah Mustafa

“On the last day of the last month, I will go”: A qualitative exploration of COVID-19 vaccine confidence among Ivoirian adults

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Open access
“On the last day of the last month, I will go”: A qualitative exploration of COVID-19 vaccine confidence among Ivoirian adults
Natalie J. Tibbels, Abdul Dosso, Corinne Fordham, William Benie, … Danielle A. Naugle
Pages 2028-2035

Public perceptions and the willingness to get vaccinated against COVID-19: Lessons from Israel

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Full text access
Public perceptions and the willingness to get vaccinated against COVID-19: Lessons from Israel
Oren Heller, Yung Chun, Yaniv Shlomo, Ateret Gewirtz-Meydan, … Michal Grinstein-Weiss

Conspiracy theories and misinformation about COVID-19 in Nigeria: Implications for vaccine demand generation communications

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Vaccine
Volume 40, Issue 13 Pages 1913-2122 (18 March 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/13

 

Research article Open access
Conspiracy theories and misinformation about COVID-19 in Nigeria: Implications for vaccine demand generation communications
Chizoba Wonodi, Chisom Obi-Jeff, Funmilayo Adewumi, Somto Chloe Keluo-Udeke, … Ruth Faden

Pre-Print Servers

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Pre-Print Servers

 

Gates Open Research
https://gatesopenresearch.org/browse/articles

Open Letter metrics AWAITING PEER REVIEW
Women’s groups and COVID-19: An evidence review on savings groups in Africa [version 1; peer review: awaiting peer review]
Olayinka Adegbite, Leigh Anderson, Sybil Chidiac, Osasuyi Dirisu, Jenna Grzeslo, Julia Hakspiel, Chinmaya Holla, Emily Janoch, Krishna Jafa, Shubha Jayaram, Grace Majara, Tabitha Mulyampiti, Eve Namisango, Eva Noble, Bukola Onyishi, David Panetta, Garima Siwach, Munshi Sulaiman, Rebecca Walcott, Sapna Desai, Thomas de Hoop
Peer Reviewers Invited
Funder
The Bill and Melinda Gates Foundation
PUBLISHED 12 Apr 2022

 

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…

COVID-19 vaccine coverage among immigrants and refugees in Alberta: a population-based cross-sectional study
Shannon E MacDonald, Yuba Raj Paudel, Crystal Du
medRxiv 2022.04.11.22273644; doi: https://doi.org/10.1101/2022.04.11.22273644

Can We Really Trust the Findings of the COVID-19 Research? Quality Assessment of Randomized Controlled Trials Published on COVID-19
Athira S Joshy, Christy Thomas, Saphal Surendran, Krishna Undela
medRxiv 2022.04.15.22273881; doi: https://doi.org/10.1101/2022.04.15.22273881

Mondo: Unifying diseases for the world, by the world
Nicole A Vasilevsky, Nicolas A Matentzoglu, Sabrina Toro, Joe E Flack, Harshad Hegde, Deepak R Unni, Gioconda Alyea, Joanna S Amberger, Larry Babb, James P Balhoff, Taylor I Bingaman, Gully A Burns, Tiffany J Callahan, Leigh C Carmody, Lauren E Chan, George S Chang, Michel Dumontier, Laura E Failla, May J Flowers, H A Garrett Jr., Dylan Gration, Tudor Groza, Marc Hanauer, Nomi L Harris, Ingo Helbig, Jason A Hilton, Daniel S Himmelstein, Charles T Hoyt, Megan S Kane, Sebastian Kohler, David Lagorce, Martin Larralde, Antonia Lock, Irene Lopez Santiago, Donna R Maglott, Adriana J Malheiro, Birgit HM Meldal, Julie A McMurry, Moni Munoz-Torres, Tristan H Nelson, David Ochoa, Tudor I Oprea, David Osumi-Sutherland, Helen Parkinson, Zoe M Pendlington, Ana Rath, Heidi L Rehm, Lyubov Remennik, Erin R Riggs, Paola Roncaglia, Justyne E Ross, Marion F Shadbolt, Kent A Shefchek, Morgan N Similuk, Nicholas Sioutos, Rachel Sparks, Ray Stefancsik, Ralf Stephan, Doron Stupp, Jagadish Chandrabose Sundaramurthi, Imke Tammen, Courtney L Thaxton, Eloise Valasek, Alex H Wagner, Danielle Welter, Patricia L Whetzel, Lori L Whiteman, Valerie Wood, Colleen H Xu, Andreas Zankl, Xingmin A Zhang, Christopher G Chute, Peter N Robinson, Christopher J Mungall, Ada Hamosh, Melissa A Haendel
medRxiv 2022.04.13.22273750; doi: https://doi.org/10.1101/2022.04.13.22273750
There are thousands of distinct disease entities and concepts, each of which are known by different and sometimes contradictory names. The lack of a unified system for managing these entities poses a major challenge for both machines and humans that need to harmonize information to better predict causes and treatments for disease. The Mondo Disease Ontology is an open, community-driven ontology that integrates key medical and biomedical terminologies, supporting disease data integration to improve diagnosis, treatment, and translational research. Mondo records the sources of all data and is continually updated, making it suitable for research and clinical applications that require up-to-date disease knowledge.

Triangulating evidence in health sciences with Annotated Semantic Queries
Yi Liu, Tom R Gaunt
medRxiv 2022.04.12.22273803; doi: https://doi.org/10.1101/2022.04.12.22273803

Profile of Brazilian inpatients with COVID-19 vaccine breakthrough infection and risk factors for unfavorable outcome
Matheus Alexandre Santos de Jesus, Natália Satchiko Hojo-Souza, Thiago Rocha de Moraes, Daniel Ludovico Guidoni, Fernanda Sumika Hojo Souza
medRxiv 2022.04.12.22273589; doi: https://doi.org/10.1101/2022.04.12.22273589

Effectiveness of COVID-19 vaccines against hospitalization and death in Canada: A multiprovincial test-negative design study
Sharifa Nasreen, Yossi Febriani, Héctor Alexander Velásquez García, Geng Zhang, Mina Tadrous, Sarah A. Buchan, Christiaan H. Righolt, Salaheddin M. Mahmud, Naveed Zafar Janjua, Mel Krajden, Gaston De Serres, Jeffrey C. Kwong
medRxiv 2022.04.13.22273825; doi: https://doi.org/10.1101/2022.04.13.22273825

Health Economic Burden of COVID-19 in Saudi Arabia
Khalidah A. Alenzi, Hamdan S. Al-malky, Ali F. Altebainawi, Hamidah Q. Abushomi, Fahad O. Alatawi, Moosa H. Atwadi, Moosa A. Khobrani, Dlal A. Almazrou, Nariman Alrubeh, Zainab A. Alsoliabi, Abdulaziz M. Kardam, Shakr A. Alghamdi, Abdulrahman Alasiri, Thamir M. Alshammari
medRxiv 2022.04.08.22273439; doi: https://doi.org/10.1101/2022.04.08.22273439

Effectiveness of the BNT162b vaccine fourth dose in reducing SARS-CoV-2 infection among healthcare workers in Israel, a multi-center cohort study
Matan J Cohen, Yonatan Oster, Allon E Moses, Avishay Spitzer, Shmuel Benenson, the Israeli-hospitals 4th vaccine Working Group
medRxiv 2022.04.11.22273327; doi: https://doi.org/10.1101/2022.04.11.22273327

The relation between COVID-19 vaccinations and public governance to improve preparedness of next pandemic impacts and crisis management: a global study
Mario Coccia, Igor Benati
medRxiv 2022.04.10.22273663; doi: https://doi.org/10.1101/2022.04.10.22273663
Abstract
The goal of this study is to analyze the relationship between COVID-19 vaccinations and public governance performing a global analysis of more than 110 countries worldwide. Methodology applies the Independent Samples T-Test that compares the means of two independent groups (countries with high/low level of vaccinations) to determine whether there is statistical evidence that the associated population means of indicators of public governance are significantly different. Findings suggest that high levels of governance can support a better function of health systems in the rollout of vaccinations to cope with COVID-19 pandemic crisis. This study may assist long-run policy of governments to improve good governance and health systems of countries in order to reinforce the preparedness to face next pandemic threats and in general future crisis management in society.

Economic vulnerability and poor service delivery made it more difficult for shack-dwellers to comply with COVID-19 restrictions: The impracticability and inequitable burden of universal/unstratified public health policies
GTH Ellison, RB Mattes, H Rhoma, T De Wet
medRxiv 2022.04.07.22273499; doi: https://doi.org/10.1101/2022.04.07.22273499

COVID-19 vaccine for people who live and work in prisons worldwide: A scoping review
Nasrul Ismail, Lara Tavoschi, Babak Moazen, Alicia Roselló, Emma Plugge
medRxiv 2022.04.07.22273414; doi: https://doi.org/10.1101/2022.04.07.22273414

Novel Privacy Considerations for Large Scale Proteomics
Andrew C. Hill, Elizabeth M. Litkowski, Ani Manichaikul, Leslie Lange, Katherine A. Pratte, Katerina J. Kechris, Matthew DeCamp, Marilyn Coors, Victor E. Ortega, Stephen S. Rich, Jerome I. Rotter, Robert E. Gerzsten, Clary B. Clish, Jeffery Curtis, Xiaowei Hu, Debby Ngo, Wanda K O’Neal, Deborah Meyers, Eugene Bleecker, Brian D. Hobbs, Michael H. Cho, Farnoush Banaeikashani, Russell P. Bowler
medRxiv 2022.04.06.22269907; doi: https://doi.org/10.1101/2022.04.06.22269907

COVID-19 Vaccination Mandates and Vaccine Uptake
Alexander Karaivanov, Dongwoo Kim, Shih En Lu, Hitoshi Shigeoka
medRxiv 2021.10.21.21265355; doi: https://doi.org/10.1101/2021.10.21.21265355 Revision

Acceptance of and preference for COVID-19 vaccination in healthcare workers: a comparative analysis and discrete choice experiment
Chuanxi Fu, Zheng wei, Fengchang Zhu, Sen Pei, Shunping Li, Liuren Zhang, Xiaohui Sun, Yue Wu, Ping Liu, Mark Jit
medRxiv 2020.04.09.20060103; doi: https://doi.org/10.1101/2020.04.09.20060103 Revision

SARS-CoV-2 reinfections with BA.1 (Omicron) variant among fully vaccinated individuals in the northeast of Brazil
Francisco P. F. Neto, Diego G. Teixeira, Dayse C. S. da Cunha, Ingryd C. Morais, Celisa P. M. Tavares, Genilson P. Gurgel, Sanderson D. do Nascimento, David C. dos Santos, Alexandre de O. Sales, Selma M.B. Jerônimo
medRxiv 2022.04.08.22272726; doi: https://doi.org/10.1101/2022.04.08.22272726

Wellcome Open Research [to 23 Apr 2022]
https://wellcomeopenresearch.org/browse/articles
[Accessed 23 Apr 2022]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Data Note metrics AWAITING PEER REVIEW
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples [version 1; peer review: awaiting peer review]
MalariaGEN, Ishag Adam, Mohammad Shafiul Alam, Sisay Alemu, Chanaki Amaratunga, Roberto Amato, Voahangy Andrianaranjaka, Nicholas M Anstey, Abraham Aseffa, Elizabeth Ashley, Ashenafi Assefa, Sarah Auburn, Bridget E Barber, Alyssa Barry, Dhelio Batista Pereira, Jun Cao, Nguyen Hoang Chau, Kesinee Chotivanich, Cindy Chu, Arjen M. Dondorp, Eleanor Drury, Diego F. Echeverry, Berhanu Erko, Fe Espino, Rick Fairhurst, Abdul Faiz, María Fernanda Villegas, Qi Gao, Lemu Golassa, Sonia Goncalves, Matthew J Grigg, Yaghoob Hamedi, Tran Tinh Hien, Ye Htut, Kimberly J Johnson, Nadira Karunaweera, Wasif Khan, Srivicha Krudsood, Dominic P Kwiatkowski, Marcus Lacerda, Benedikt Ley, Pharath Lim, Yaobao Liu, Alejandro Llanos-Cuentas, Chanthap Lon, Tatiana Lopera-Mesa, Jutta Marfurt, Pascal Michon, Olivo Miotto, Rezika Mohammed, Ivo Mueller, Chayadol Namaik-larp, Paul N Newton, Thuy-Nhien Nguyen, Francois Nosten, Rintis Noviyanti, Zuleima Pava, Richard D Pearson, Beyene Petros, Aung P Phyo, Ric N Price, Sasithon Pukrittayakamee, Awab Ghulam Rahim, Milijaona Randrianarivelojosia, Julian C Rayner, Angela Rumaseb, Sasha V Siegel, Victoria J Simpson, Kamala Thriemer, Alberto Tobon-Castano, Hidayat Trimarsanto, Marcelo Urbano Ferreira, Ivan D Vélez, Sonam Wangchuk, Thomas E Wellems, Nicholas J White, Timothy William, Maria F Yasnot, Daniel Yilma
Peer Reviewers Invited
Funders
Wellcome Trust
Medical Research Council UK and the Department for International Development (DFID)
Bill and Melinda Gates Foundation
PUBLISHED 14 Apr 2022

Research Article metrics
Revised
Stage 2 Registered Report: How responsibility attributions to self and others relate to outcome ownership in group decisions [version 2; peer review: 2 approved]
Matt Jaquiery, Marwa El Zein
Peer Reviewers John A. Dewey; Nura Sidarus
Funders
Wellcome Trust
Medical Research Council
University of Oxford
LATEST VERSION PUBLISHED 11 Apr 2022

Research Article metrics
Revised
A survey to gather perspectives of DBT/Wellcome Trust India Alliance-funded researchers on public engagement with science [version 2; peer review: 2 approved]
Sarah Iqbal, Banya Kar
Peer Reviewers Marina Joubert; Mary Chambers and Han Dong Thai Tran
Funder
DBT/Wellcome Trust India Alliance
LATEST VERSION PUBLISHED 08 Apr 2022

Think Tanks

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Think Tanks
 
 
Brookings
http://www.brookings.edu/
Accessed 23 Apr 2022
[No new digest content identified]
 
 
Center for Global Development [to 23 Apr 2022]
https://www.cgdev.org/
Research [Selected]
POLICY PAPERS
Beyond India’s Lockdown: PMGKY Benefits During the COVID-19 Crisis and the State of Digital Payments
Alan Gelb et al.
April 11, 2022
India imposed a lock-down in response to the COVID-19 pandemic in March 2020 and began a gradual re-opening in June. A telephonic survey in April examined the early effectiveness of information and the massive PMGKY social protection program (Policy Paper 217). This paper analyzes a second-round sur…
 
 
Chatham House [to 23 Apr 2022]
https://www.chathamhouse.org/
Accessed 23 Apr 2022
[No new digest content identified]

 
 
CSIS
https://www.csis.org/
Accessed 23 Apr 2022
Upcoming Event
Equity in Immunization Services to Ensure “A Long Life for All”
April 28, 2022

Upcoming Event
Innovation and IP’s Role in Combatting the Covid-19 Pandemic
April 27, 2022

Upcoming Event
AMR as a Global Security Threat: Destabilizing Food Systems and Healthy Communities
April 25, 2022

Commentary
Removing Patent Rights to Lower Drug Costs Is a Dangerous Precedent
April 14, 2022 | By Walter G. Copan

 
 
Kaiser Family Foundation
https://www.kff.org/search/?post_type=press-release
Accessed 23 Apr 2022
Accessed 23 Apr 2022
[No new digest content identified]
 
 
ODI [Overseas Development Institute] [to 23 Apr 2022]
https://odi.org/en/publications/
Publications
Accessed 23 Apr 2022
[No new digest content identified]
 
 
Rand [to 23 Apr 2022]
https://www.rand.org/pubs.html
Reports, Selected Journal Articles
Report
How Extremism Operates Online: A Primer
In this Perspective, the second in a RAND Corporation series on online extremist material, the authors explore how the internet affects extremist activities and how exposure to or consumption of such content influences the behavior of internet users.
Apr 12, 2022
Alexandra T. Evans, Heather J. Williams
 
 
Urban Institute [to 23 Apr 2022]
https://www.urban.org/publications
Research Publications
Brief
Best Practices in Education to Inform an Equitable COVID-19 Recovery
April 12, 2022

Brief
Best Practices in Safety Net Programs to Inform an Equitable COVID-19 Recovery
April 12, 2022

Brief
Best Practices in Housing, Transportation, and Infrastructure to Inform an Equitable COVID-19 Recovery
April 12, 2022

Brief
Best Practices in Small Business Recovery to Inform an Equitable COVID-19 Recovery
April 12, 2022

Brief
Best Practices in Employment to Inform an Equitable COVID-19 Recovery
April 12, 2022

Brief
Best Practices in Local Revenue Recovery to Inform an Equitable COVID-19 Recovery
April 12, 2022

Vaccines and Global Health: The Week in Review :: 23 April 2022 :: Issue 6654

Posted on by

Vaccines and Global Health: The Week in Review is a weekly digest  summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated with the current issue date

.– Request an Email Summary: Vaccines and Global Health : The Week in Review is published as a single email summary, scheduled for release each Saturday evening before midnight (EDT in the U.S.). If you would like to receive the email version, please send your request to david.r.curry@centerforvaccineethicsandpolicy.org.

– pdf version:  A pdf of the current issue is available here:

vaccines-and-global-health_the-week-in-review_23-april-2022_finalDownload

– blog edition: comprised of the approx. 35+ entries posted below.

– Twitter:  Readers can also follow developments on twitter: @vaxethicspolicy.
.
– Links:  We endeavor to test each link as we incorporate it into any post, but recognize that some links may become “stale” as publications and websites reorganize content over time. We apologize in advance for any links that may not be operative. We believe the contextual information in a given post should allow retrieval, but please contact us as above for assistance if necessary.

Support this knowledge-sharing service: Your financial support helps us cover our costs and to address a current shortfall in our annual operating budget. Click here to donate and thank you in advance for your contribution.

.
David R. Curry, MS
Executive Director
Center for Vaccine Ethics and Policy

Vaccines and Global Health: The Week in Review :: 16 April 2022

Posted on by

Vaccines and Global Health: The Week in Review is a weekly digest  summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated with the current issue date

.– Request an Email Summary: Vaccines and Global Health : The Week in Review is published as a single email summary, scheduled for release each Saturday evening before midnight (EDT in the U.S.). If you would like to receive the email version, please send your request to david.r.curry@centerforvaccineethicsandpolicy.org.

– pdf version:  A pdf of the current issue is available here:

vaccines-and-global-health_the-week-in-review_16-april-2022Download

– blog edition: comprised of the approx. 35+ entries posted below.

– Twitter:  Readers can also follow developments on twitter: @vaxethicspolicy.
.
– Links:  We endeavor to test each link as we incorporate it into any post, but recognize that some links may become “stale” as publications and websites reorganize content over time. We apologize in advance for any links that may not be operative. We believe the contextual information in a given post should allow retrieval, but please contact us as above for assistance if necessary.

Support this knowledge-sharing service: Your financial support helps us cover our costs and to address a current shortfall in our annual operating budget. Click here to donate and thank you in advance for your contribution.

.
David R. Curry, MS
Executive Director
Center for Vaccine Ethics and Policy

SAGE April 2022 meeting highlights – WHO

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SAGE April 2022 meeting highlights – WHO
11 April 2022
SAGE Meeting of 4-7 April 2022
PDF: https://cdn.who.int/media/docs/default-source/immunization/sage/sage-pages/sage_april2022meetinghighlights_11apr2022_final.pdf?sfvrsn=c2bd9f68_1
(Full report will be published in the Weekly Epidemiological Record on 10.06.2022, and only
the wording of the full report should be considered as final)

 

Session 1 – Global & Regional Reports
Report from the WHO Department of Immunization, Vaccines & Biologicals
• The speed of the COVID-19 vaccine rollout has been unprecedented with nearly every country
introducing the vaccine in under 12 months.
• Available data of COVID-19 vaccine effectiveness against the Omicron variant generally show
waning immunity against infection but high and more sustained effectiveness against severe
disease and death, especially after booster doses. Data remain very limited for some of the WHO
EUL vaccines.
• To date, 21 countries remain below 10% population coverage, leaving at high risk the most
vulnerable populations. Among countries eligible for support through the COVAX Advance
Market Commitment (AMC) strategy at least 43 have set population targets at 70% or higher
and only a small number have targets below 40% of their population.
• However, available data indicate that coverage among the high priority groups is insufficient to
provide the needed protection against severe disease and death. Health worker coverage is 65%
overall, with coverage below 50% in some regions (Non-AMC member states), and coverage of
older adults is 69% going as low as 24% in some regions.
• Disruptions to routine immunization programmes persist, including the ongoing delay of at least
one campaign in 37 countries as of 10 January 2022, putting millions of children at risk of disease
outbreaks. Large and disruptive outbreaks of measles have occurred in at least 19 countries
during the past 12 months.
• COVID-19 vaccination response and investments offer important opportunities that are being
leveraged to restore and strengthen immunization programmes and enhance their resilience.

 

WHO Regional Updates
• National immunization programmes in all six WHO regions were adversely impacted by the
COVID-19 pandemic through declining immunization coverage and surveillance quality, though
the magnitude of the impact varied between and within regions.
• The European region is also facing a challenge due to the ongoing war in Ukraine and the
resulting large population displacement. The WHO Regional Office and partner agencies are
taking measures to mitigate the risks of vaccine-preventable disease outbreaks such as measles,
polio, and COVID-19, while also ensuring continued delivery of critical medical supplies and
services.
• All countries are implementing measures to restore vaccination coverage, with several having
identified innovative strategies for catch up vaccination.
• The rollout of COVID-19 vaccination is progressing in all regions, though vaccine uptake varies
between and within regions and disproportionately lower vaccination coverage has been
observed in low- and low-middle income countries. Vaccine hesitancy and low risk perception
are further affecting the uptake of COVID-19 vaccination in several countries.

 

Gavi report
• Reaching the zero-dose children through the building of resilient health systems remains a top
priority of the Alliance in the Gavi strategy 2021-2025 (Gavi 5.0) and is estimated to account for
over half the incremental impact of Gavi investments during the strategy period.
• A funding window for the rollout of malaria vaccines will be opened in the second half of 2022 to
enable initial vaccine introductions in 2023.
• Gavi expressed concern over the 13% decline of global HPV vaccine coverage in 2020 due to
COVID-19 disruptions, attributing this issue primarily to school closures and limited supply. It
was acknowledged that a recommendation for a single dose regimen has the potential to
accelerate introductions and reduce operational costs and complexity.
• The COVAX facility has sufficient supply available for all AMC countries to achieve the WHO 70%
coverage target by June 2022. The COVAX Vaccine Delivery Partnership is supporting countries
to overcome barriers and to achieve national coverage targets.

 

Session 2 – Immunization Agenda 2030 and catch-up vaccination
• SAGE was presented with evidence of the impact of the COVID-19 pandemic on national
immunization programmes mainly due to service delivery disruptions.
• The urgent need to close resulting immunity gaps was recognized, as was the importance of
supporting the recovery and resilience of immunization programmes and mitigating the risk of
vaccine-preventable disease outbreaks.
• SAGE recommended that countries use the COVID-19 pandemic and COVID-19 vaccination
rollout as a transformative opportunity to establish resilient immunization programmes and
strengthen primary health care. Among the specific areas identified were health worker
vaccination, immunization logistics and registries, surveillance, data and communications.
• The document “Guiding Principles for recovering, building resiliency, and strengthening of
immunization in 2022 and beyond” was endorsed and recommended for dissemination to
regional and national immunization technical advisory groups so that it may be adapted and
used for their local context.

[The full summaries for the sessions below are available at the PDF link above]
Session 3 – Hepatitis A vaccination

 

Session 4 – COVID-19 vaccines

Session 5 – Typhoid conjugate vaccination

 

Session 6 – Human Papillomavirus vaccination

Session 7 – Poliovirus vaccines

 

::::::

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer
11 April 2022
News release
The 4-7 April convening of the WHO Strategic Advisory Group of Experts on Immunization (SAGE) evaluated the evidence that has been emerging over past years that single-dose schedules provide comparable efficacy to the two or three-dose regimens.

SAGE’s review concluded that a single-dose Human Papillomavirus (HPV) vaccine delivers solid protection against HPV, the virus that causes cervical cancer, that is comparable to 2-dose schedules.  This could be a game-changer for the prevention of the disease; seeing more doses of the life-saving jab reach more girls…

“The HPV vaccine is highly effective for the prevention of HPV serotypes 16 & 18, which cause 70% of cervical cancer,” said Dr Alejandro Cravioto, SAGE Chair. “SAGE urges all countries to introduce HPV vaccines and prioritize multi-age cohort catch up of missed and older cohorts of girls. These recommendations will enable more girls and women to be vaccinated and thus preventing them from having cervical cancer and all its consequences over the course of their lifetimes.”

 

SAGE recommends updating dose schedules for HPV as follows:
one or two-dose schedule for the primary target of girls aged 9-14
one or two-dose schedule for young women aged 15-20
Two doses with a 6-month interval for women older than 21.

Immunocompromised individuals, including those with HIV, should receive three doses if feasible, and if not at least two doses. There is limited evidence regarding the efficacy of a single dose in this group.

WHO’s recommendations will be updated following further consultation across stakeholders…

Globally, the uptake of the life-saving vaccine has been slow, and coverage in countries much lower than the 90% target. Consequently, in 2020 global coverage with 2 doses was only 13%.  Several factors have influenced the slow uptake and low coverage of HPV vaccines including supply challenges, as well as the programmatic challenges and costs related to delivering a two regimen to older girls who are not typically part of childhood vaccination programs. Added to this has been the relatively high cost of HPV vaccines, particularly for middle-income countries…

The option for a single dose of the vaccine is less costly, less resource intensive and easier to administer. It facilitates implementing catch-up campaigns for multiple age groups, reduces the challenges link ed to tracing girls for their second dose and allows for financial and human resources to be redirected to other health priorities.”