Health equity and health system strengthening – Time for a WHO re-think

Global Public Health
Volume 17, Issue 3 (2022)
http://www.tandfonline.com/toc/rgph20/current

 

Article
Health equity and health system strengthening – Time for a WHO re-think
N. Jensen, A. H. Kelly & M. Avendano
Pages: 377-390
Published online: 10 Jan 2021
ABSTRACT
The pursuit of health equity is foundational to the global health enterprise. But while moral concerns over health inequities can galvanise political commitment, how such concerns can or should translate into practice remains less clear. This paper reviews evolving ways that equity goals have featured in key World Health Organization (WHO)-related policy documents, before discussing the heuristic value and empirical traction that the concept of equity can bring to the health system strengthening (HSS) agenda. We argue that while health equity is often presented as the overarching goal of HSS, in practice this is typically circumscribed to the provision of healthcare services. Although healthcare equity is important, we suggest that this narrow focus risks losing sight of the structural political, social and economic drivers of health and health inequities, as well as the broader contexts of care and complex socio-political mechanisms through which health systems are strengthened. Drawing on new lines of empirical inquiry, we propose that broadening the equity lens for HSS offers exciting opportunities to put health systems at the heart of a more ambitious equity agenda in global health.

How are global health policies transferred to sub-Saharan Africa countries? A systematic critical review of literature

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 26 Feb 2022]

 

How are global health policies transferred to sub-Saharan Africa countries? A systematic critical review of literature
Most sub-Saharan Africa countries adopt global health policies. However, mechanisms with which policy transfers occur have largely been studied amongst developed countries and much less in low- and middle- inc…
Authors: Walter Denis Odoch, Flavia Senkubuge, Ann Bosibori Masese and Charles Hongoro
Citation: Globalization and Health 2022 18:25
Content type: Research
Published on: 23 February 2022

Redressing COVID-19 vaccine inequity amidst booster doses: charting a bold path for global health solidarity, together

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 26 Feb 2022]

 

Redressing COVID-19 vaccine inequity amidst booster doses: charting a bold path for global health solidarity, together
With large swathes of the world’s population—majority clustered in low- and middle-income countries—still yet to receive the minimum of two doses of the COVID-19 vaccine; The need to address the failures of in…
Authors: Sudhan Rackimuthu, Kapil Narain, Arush Lal, Faisal A. Nawaz, Parvathy Mohanan, Mohammad Yasir Essar and Henry Charles Ashworth
Citation: Globalization and Health 2022 18:23
Content type: Commentary
Published on: 22 February 2022

Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications

JAMA
February 22, 2022, Vol 327, No. 8, Pages 703-790
https://jamanetwork.com/journals/jama/currentissue

 

Original Investigation
Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications
Torri D. Metz, MD, MS; Rebecca G. Clifton, PhD; Brenna L. Hughes, MD, MS; et al.
free access has active quiz has multimedia has audio
JAMA. 2022;327(8):748-759. doi:10.1001/jama.2022.1190
This cohort study evaluates the association of SARS-CoV-2 infection with serious maternal morbidity or mortality related to hypertensive disorders of pregnancy, postpartum hemorrhage, or infection other than SARS-CoV-2.

The US Supreme Court’s Rulings on Large Business and Health Care Worker Vaccine Mandates – Ramifications for the COVID-19 Response and the Future of Federal Public Health Protection

JAMA
February 22, 2022, Vol 327, No. 8, Pages 703-790
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
The US Supreme Court’s Rulings on Large Business and Health Care Worker Vaccine Mandates – Ramifications for the COVID-19 Response and the Future of Federal Public Health Protection
Lawrence O. Gostin, JD; Wendy E. Parmet, JD; Sara Rosenbaum, JD
JAMA. 2022;327(8):713-714. doi:10.1001/jama.2022.0852
This Viewpoint examines the recent US Supreme Court rulings on government mandates for COVID-19 vaccination and how these decisions might affect the ongoing pandemic response as well as the future of public health.

COVID-19 and Pregnancy

JAMA
February 22, 2022, Vol 327, No. 8, Pages 703-790
https://jamanetwork.com/journals/jama/currentissue

 

JAMA Patient Page
COVID-19 and Pregnancy
Kristin Walter, MD, MS
free access has multimedia has audio
JAMA. 2022;327(8):790. doi:10.1001/jama.2021.22679
This JAMA Patient Page describes characteristics of COVID-19 among pregnant people and vaccination recommendations for people who are pregnant or breastfeeding.

Waning effectiveness of COVID-19 vaccines

The Lancet
Feb 26, 2022 Volume 399 Number 10327 p769-884, e7-e10
https://www.thelancet.com/journals/lancet/issue/current

 

Comment
Waning effectiveness of COVID-19 vaccines
Hiam Chemaitelly, Laith J Abu-Raddad
In The Lancet, Peter Nordström and colleagues1 report the effectiveness of several COVID-19 vaccines and different vaccine schedules against any documented SARS-CoV-2 infection and against severe COVID-19, for up to 9 months of follow-up. Data for 842 974 matched pairs of vaccinated and unvaccinated individuals in this retrospective cohort study were retrieved from the Swedish national registers. These registers track health outcomes for all registered individuals nationwide. Both cohorts had a median age of 52·7 years (IQR 37·0–67·5) and included mostly women (500 297 [59·3%] in each cohort) and individuals born in Sweden (703 666 [83·5%] in the vaccinated cohort vs 578 647 [68·6%] in the unvaccinated cohort). Follow-up started 14 days after the second dose for each person vaccinated with BNT162b2 (Pfizer–BioNTech), mRNA-1273 (Moderna), ChAdOx1 nCoV-19 (Oxford–AstraZeneca), or mixed ChAdOx1 nCoV-19 and an mRNA vaccine and their unvaccinated matches. Effectiveness estimates were adjusted for date of second dose, age, sex, domestic support (proxy for disability), education, place of birth, and comorbidities. The study was completed on Oct 4, 2021, before the advent of the omicron (B.1.1.529) variant…

Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden

The Lancet
Feb 26, 2022 Volume 399 Number 10327 p769-884, e7-e10
https://www.thelancet.com/journals/lancet/issue/current

 

Articles
Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden
Peter Nordström, Marcel Ballin, Anna Nordström

COVID-19: talk of ‘vaccine hesitancy’ lets governments off the hook

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Comment | 22 February 2022
COVID-19: talk of ‘vaccine hesitancy’ lets governments off the hook
Go beyond the attitudes of individuals and focus more on what governments must do to build people’s trust and ensure easy access to vaccines for all.
Katie Attwell, Adam Hannah, Julie Leask

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 23 December 2021 | Open Access
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Plasma from individuals vaccinated with BNT162b2 exhibits 22-fold less neutralization capacity against Omicron (B.1.1.529) than against an ancestral SARS-CoV-2 strain but residual neutralization is maintained in those with high levels of neutralization of ancestral virus.
Sandile Cele, Laurelle Jackson, Alex Sigal

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 23 December 2021 | Open Access
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
A high-throughput yeast display platform is used to analyse the profiles of mutations in the SARS-CoV-2 receptor-binding domain (RBD) that enable escape from antibodies, and suggests that most anti-RBD antibodies can be escaped by the Omicron variant.
Yunlong Cao, Jing Wang, Xiaoliang Sunney Xie

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 23 December 2021
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Pseudovirus assays and surface plasmon resonance show that the Omicron receptor-binding domain binds to human ACE2 with increased affinity relative to the ancestral virus, and that most neutralizing antibodies are considerably less potent against Omicron.
Elisabetta Cameroni, John E. Bowen, Davide Corti

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 23 December 2021
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
An isolate of the Omicron variant of SARS-COV-2 was completely or partially resistant to neutralization by all nine clinically approved monoclonal antibodies tested.
Delphine Planas, Nell Saunders, Olivier Schwartz

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 23 December 2021
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
The B.1.1.529/Omicron variant of SARS-CoV-2 is resistant to neutralization by serum not only from patients who recovered from COVID-19, but also from individuals vaccinated with one of the four widely used COVID-19 vaccines.
Lihong Liu, Sho Iketani, David D. Ho

Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

Nature
Volume 602 Issue 7898, 24 February 2022
https://www.nature.com/nature/volumes/602/issues/7898

 

Article | 31 December 2021
Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron
Sera from unvaccinated, vaccinated, and previously infected and vaccinated individuals show reduced neutralizing and spike protein-binding activity towards the Omicron (B.1.1.529) variant of SARS-CoV-2 compared to other variants.
Juan Manuel Carreño, Hala Alshammary, Florian Krammer

Focus on vaccine inequity

Nature Human Behaviour
Volume 6 Issue 2, February 2022
https://www.nature.com/nathumbehav/volumes/6/issues/2

 

Focus on vaccine inequity
Equitable distribution of resources to fight COVID-19 is a global challenge. In a collection of research and opinion articles, researchers, public health officials, intellectual property experts, leaders of international organizations, and activists explain how global inequities in COVID-19 vaccine allocation continue fuelling the pandemic, and discuss ways to address these disparities.

In a pandemic, national and global interests converge

Nature Human Behaviour
Volume 6 Issue 2, February 2022
https://www.nature.com/nathumbehav/volumes/6/issues/2

 

Editorial | 31 January 2022
In a pandemic, national and global interests converge
In ten contributions, mathematical modellers, public health officials, intellectual property experts and activists explain how vaccine inequities continue to fuel the pandemic, and how multilateral cooperation can help.

Vaccine inequity is unethical

Nature Human Behaviour
Volume 6 Issue 2, February 2022
https://www.nature.com/nathumbehav/volumes/6/issues/2

 

World View | 31 January 2022
Vaccine inequity is unethical
Ethical principles dictate that limited, life-saving resources should be allocated fairly. Keymanthri Moodley affirms that achieving global distributive justice is one of the greatest challenges of the COVID-19 pandemic, and current distribution strategies are ethically indefensible.
Keymanthri Moodley

The emergence of COVID-19 vaccine resistance depends on human choices

Nature Human Behaviour
Volume 6 Issue 2, February 2022
https://www.nature.com/nathumbehav/volumes/6/issues/2

 

Research Briefing | 24 February 2022
The emergence of COVID-19 vaccine resistance depends on human choices
The probability of the emergence of SARS-CoV-2 vaccine-resistant variants depends on the number of daily infections permitted by society, and the rate and penetrance of vaccination. Rapidly vaccinating all eligible people while maintaining strict physical distancing measures can prevent the evolution of vaccine resistance.

Equitable access to COVID-19 vaccines makes a life-saving difference to all countries

Nature Human Behaviour
Volume 6 Issue 2, February 2022
https://www.nature.com/nathumbehav/volumes/6/issues/2

 

Article | 31 January 2022 | Open Access
Equitable access to COVID-19 vaccines makes a life-saving difference to all countries
Using data-driven mathematical modelling that combines viral evolution with epidemiological dynamics, Ye et al. show that COVID-19 vaccine inequity leads to the emergence of new variants and new waves of the pandemic, while equitable allocation of vaccine doses reduces case counts and fatalities in all countries.
Yang Ye, Qingpeng Zhang, Daniel Dajun Zeng

The French health pass holds lessons for mandatory COVID-19 vaccination

Nature Medicine
Volume 28 Issue 2, February 2022
https://www.nature.com/nm/volumes/28/issues/2

 

Comment | 12 January 2022
The French health pass holds lessons for mandatory COVID-19 vaccination
The passe sanitaire increased levels of vaccination, but to a lower extent among the most vulnerable, and did not reduce vaccine hesitancy itself, showing the importance of outreach to underserved communities and the potential limits of mandatory vaccination policies.
Jeremy K. Ward, Fatima Gauna, Patrick Peretti-Watel

A roadmap to increase diversity in genomic studies

Nature Medicine
Volume 28 Issue 2, February 2022
https://www.nature.com/nm/volumes/28/issues/2

 

Perspective | 10 February 2022
A roadmap to increase diversity in genomic studies
Based on their experience of setting up genomic studies in underrepresented populations, the authors propose a roadmap to enhancing inclusion and ensuring that the health benefits of genomics advances are accessible to all.
Segun Fatumo, Tinashe Chikowore, Karoline Kuchenbaecker

Influenza virus infection history shapes antibody responses to influenza vaccination

Nature Medicine
Volume 28 Issue 2, February 2022
https://www.nature.com/nm/volumes/28/issues/2

 

Article | 17 February 2022
Influenza virus infection history shapes antibody responses to influenza vaccination
Recent prior influenza A infection is associated with elevated hemagglutinin-inhibiting antibody responses and greater breadth of reactivity to influenza strains following vaccination, suggesting that infection history boosts vaccine responses.
Maria Auladell, Hoang Vu Mai Phuong, Annette Fox

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection

Nature Medicine
Volume 28 Issue 2, February 2022
https://www.nature.com/nm/volumes/28/issues/2

 

Article | 14 December 2021 | Open Access
Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection
A self-controlled case series using individual-patient-level data from over 38 million people aged 16 years and over, reveals an increased risk of myocarditis within a week of receiving a first dose of ChAdOx1, BNT162b2 and mRNA-1273 vaccines, which was further increased after a second dose of either mRNA vaccine. SARS-CoV-2 infection was associated with even greater risk of myocarditis, as well as pericarditis and cardiac arrhythmia.
Martina Patone, Xue W. Mei, Julia Hippisley-Cox

First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 26 Feb 2022)

 

First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales
Steven Kerr, Mark Joy, Fatemeh Torabi, Stuart Bedston, Ashley Akbari, Utkarsh Agrawal, Jillian Beggs, Declan Bradley, Antony Chuter, Annemarie B. Docherty, David Ford, Richard Hobbs, Srinivasa Vittal Katikireddi, Emily Lowthian, Simon de Lusignan, Ronan Lyons, James Marple, Colin McCowan, Dylan McGagh, Jim McMenamin, Emily Moore, Josephine-L. K. Murray, Rhiannon K. Owen, Jiafeng Pan, Lewis Ritchie, Syed Ahmar Shah, Ting Shi, Sarah Stock, Ruby S. M. Tsang, Eleftheria Vasileiou, Mark Woolhouse, Colin R. Simpson, Chris Robertson, Aziz Sheikh
Research Article | published 22 Feb 2022 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003927

Uptake of infant and preschool immunisations in Scotland and England during the COVID-19 pandemic: An observational study of routinely collected data

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 26 Feb 2022)

 

Uptake of infant and preschool immunisations in Scotland and England during the COVID-19 pandemic: An observational study of routinely collected data
Fiona McQuaid, Rachel Mulholland, Yuma Sangpang Rai, Utkarsh Agrawal, Helen Bedford, J. Claire Cameron, Cheryl Gibbons, Partho Roy, Aziz Sheikh, Ting Shi, Colin R. Simpson, Judith Tait, Elise Tessier, Steve Turner, Jaime Villacampa Ortega, Joanne White, Rachael Wood
Research Article | published 22 Feb 2022 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003916

Measles containing vaccine coverage and factors associated with its uptake among children aged 24–59 months in Cherangany Sub County, Trans Nzoia County, Kenya

PLoS One
http://www.plosone.org/
[Accessed 26 Feb 2022]

 

Measles containing vaccine coverage and factors associated with its uptake among children aged 24–59 months in Cherangany Sub County, Trans Nzoia County, Kenya
Stella Mamuti, Collins Tabu, Irene Marete, Davies Opili, Rose Jalang’o, Ahmed Abade
Research Article | published 23 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0263780

Determinants of acceptance of Coronavirus disease-2019 (COVID-19) vaccine among Lebanese health care workers using health belief model

PLoS One
http://www.plosone.org/
[Accessed 26 Feb 2022]

 

Determinants of acceptance of Coronavirus disease-2019 (COVID-19) vaccine among Lebanese health care workers using health belief model
Dalal Youssef, Linda Abou-Abbas, Atika Berry, Janet Youssef, Hamad Hassan
Research Article | published 22 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0264128

Media attention and Vaccine Hesitancy: Examining the mediating effects of Fear of COVID-19 and the moderating role of Trust in leadership

PLoS One
http://www.plosone.org/
[Accessed 26 Feb 2022]

 

Media attention and Vaccine Hesitancy: Examining the mediating effects of Fear of COVID-19 and the moderating role of Trust in leadership
Lulin Zhou, Sabina Ampon-Wireko, Xinglong Xu, Prince Edwudzie Quansah, Ebenezer Larnyo
Research Article | published 18 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0263610

Understanding the Facilitators and Barriers to COVID-19 Vaccine Uptake Among Teachers in the Sagnarigu Municipality of Northern Ghana: A Cross-Sectional Study

Risk Management and Healthcare Policy
https://www.dovepress.com/risk-management-and-healthcare-policy-archive56
[Accessed 26 Feb 2022]

 

Original Research
Understanding the Facilitators and Barriers to COVID-19 Vaccine Uptake Among Teachers in the Sagnarigu Municipality of Northern Ghana: A Cross-Sectional Study
Dubik SD
Published Date: 24 February 2022