Category Archives: Uncategorized

Outcomes from the Use of Targeted Interventions to Increase Meningococcal Vaccination Rates in a Pediatric Clinic

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Journal of Community Health
Volume 47, issue 1, February 2022
https://link.springer.com/journal/10900/volumes-and-issues/47-1

 

Outcomes from the Use of Targeted Interventions to Increase Meningococcal Vaccination Rates in a Pediatric Clinic
Authors (first, second and last of 5)
Lindsay Podraza, Jayan Vasudevan, Meera Varman
Content type: Original Paper
Published: 13 August 2021
Pages: 87 – 93

Offline: Complacency threatens progress against COVID-19

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The Lancet
Feb 12, 2022 Volume 399 Number 10325 p605-694
https://www.thelancet.com/journals/lancet/issue/current

 

Comment
Offline: Complacency threatens progress against COVID-19
Richard Horton
Hans Kluge, WHO’s Regional Director for Europe, has been reported as saying that European nations could soon be entering a “long period of tranquillity” as the pandemic abates. Pointing out that mortality from COVID-19 seemed to be plateauing, he suggested the continent was approaching a “plausible endgame” and an “enduring peace”. As WHO’s chief spokesperson for the 53 countries that make up his regional responsibility, Kluge was no doubt seeking to strike an optimistic and encouraging note. But it is disappointing that he took such a narrow geographical perspective about a global pandemic. His words promote a false reassurance that could breed complacency, even conceit…

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

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The Lancet
Feb 12, 2022 Volume 399 Number 10325 p605-694
https://www.thelancet.com/journals/lancet/issue/current

 

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
RECOVERY Collaborative Group
Open Access

Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

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Nature
Volume 602 Issue 7896, 10 February 2022
https://www.nature.com/nature/volumes/602/issues/7896

 

Article | 22 December 2021 | Open Access
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta
The Alpha variant of SARS-CoV-2 outcompetes progenitor SARS-CoV-2 in upper respiratory tract replication competition in vivo.
Lorenz Ulrich, Nico Joel Halwe, Charaf Benarafa

Local and systemic responses to SARS-CoV-2 infection in children and adults

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Nature
Volume 602 Issue 7896, 10 February 2022
https://www.nature.com/nature/volumes/602/issues/7896

 

Article | 22 December 2021 | Open Access
Local and systemic responses to SARS-CoV-2 infection in children and adults
Mechanisms explaining the milder clinical syndrome that is observed in children with SARS-CoV-2 infection.
Masahiro Yoshida, Kaylee B. Worlock, Kerstin B. Meyer

Our genes, our microbes

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Nature Genetics
Volume 54 Issue 2, February 2022
https://www.nature.com/ng/volumes/54/issues/2

 

Editorial | 11 February 2022
Our genes, our microbes
In recent years, large-scale genomic studies have been performed in attempts to determine how genetic variation in the human host influences the gut microbiome. As microbiome traits are very heterogeneous, new analytical approaches are needed to move this field forward. By using genetic tools, there is a huge opportunity to enrich our understanding of the complex link between humans and our intimately associated microbial species.

Challenges and future directions for studying effects of host genetics on the gut microbiome

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Nature Genetics
Volume 54 Issue 2, February 2022
https://www.nature.com/ng/volumes/54/issues/2

 

Perspective | 03 February 2022
Challenges and future directions for studying effects of host genetics on the gut microbiome
This Perspective discusses the analytical issues concerning heterogeneity and power encountered in microbial genome-wide association studies and highlights potential future directions for genetic analysis of the microbiome.
Serena Sanna, Alexander Kurilshikov, Alexandra Zhernakova

Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico

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New England Journal of Medicine
February 10, 2022 Vol. 386 No. 6
https://www.nejm.org/toc/nejm/medical-journal

 

Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico L.M. Dunkle and Others
NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle vaccine that was shown to have clinical efficacy for the prevention of coronavirus disease 2019 (Covid-19) in phase 2b–3 trials in the United Kingdom and South Africa, but its efficacy had not yet been tested in North America.

Information nudges for influenza vaccination: Evidence from a large-scale cluster-randomized controlled trial in Finland

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PLoS Medicine
http://www.plosmedicine.org/
(Accessed 12 Feb 2022)

 

Information nudges for influenza vaccination: Evidence from a large-scale cluster-randomized controlled trial in Finland
Lauri Sääksvuori, Cornelia Betsch, Hanna Nohynek, Heini Salo, Jonas Sivelä, Robert Böhm
Research Article | published 09 Feb 2022 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003919

Perceptions of risk of SARS-CoV-2 transmission in social and educational activities by infectious diseases and general pediatric healthcare providers, a pre-vaccine risk perception cross-sectional survey

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PLoS One
http://www.plosone.org/
[Accessed 12 Feb 2022]

 

Research Article
Perceptions of risk of SARS-CoV-2 transmission in social and educational activities by infectious diseases and general pediatric healthcare providers, a pre-vaccine risk perception cross-sectional survey
Andrew B. Janowski, Philip M. Polgreen, Susan E. Beekmann, Jason G. Newland
Research Article | published 11 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0263767

Factors affecting intention to take COVID-19 vaccine among Pakistani University Students

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PLoS One
http://www.plosone.org/
[Accessed 12 Feb 2022]

 

Factors affecting intention to take COVID-19 vaccine among Pakistani University Students
Mosharop Hossian, Md Abdullah Saeed Khan, Anum Nazir, Mohammad Hayatun Nabi, Mehedi Hasan, Ramisha Maliha, Mohammad Ali Hossain, Md Utba Rashid, Nizwa Itrat, Mohammad Delwer Hossain Hawlader
Research Article | published 11 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0262305

Attitudes towards influenza, and COVID-19 vaccines during the COVID-19 pandemic among a representative sample of the Jewish Israeli population

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PLoS One
http://www.plosone.org/
[Accessed 12 Feb 2022]

 

Attitudes towards influenza, and COVID-19 vaccines during the COVID-19 pandemic among a representative sample of the Jewish Israeli population
Yasmin Maor, Shaked Caspi
Research Article | published 11 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0255495

Misinformation, believability, and vaccine acceptance over 40 countries: Takeaways from the initial phase of the COVID-19 infodemic

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PLoS One
http://www.plosone.org/
[Accessed 12 Feb 2022]

 

Misinformation, believability, and vaccine acceptance over 40 countries: Takeaways from the initial phase of the COVID-19 infodemic
Karandeep Singh, Gabriel Lima, Meeyoung Cha, Chiyoung Cha, Juhi Kulshrestha, Yong-Yeol Ahn, Onur Varol
Research Article | published 09 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0263381

The impact of risk perceptions and belief in conspiracy theories on COVID-19 pandemic-related behaviours

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PLoS One
http://www.plosone.org/
[Accessed 12 Feb 2022]

 

The impact of risk perceptions and belief in conspiracy theories on COVID-19 pandemic-related behaviours
Jack P. Hughes, Alexandros Efstratiou, Sara R. Komer, Lilli A. Baxter, Milica Vasiljevic, Ana C. Leite
Research Article | published 08 Feb 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0263716

Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave

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PNAS – Proceedings of the National Academy of Sciences of the United States
January 11, 2022; vol. 119 no. 3
https://www.pnas.org/content/119/3

 

Biophysics and Computational Biology
Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave
Nathaniel Hupert, Daniela Marín-Hernández, Bo Gao, Ricardo Águas, and Douglas F. Nixon
PNAS January 18, 2022 119 (3) e2025448119; https://doi.org/10.1073/pnas.2025448119

Politicians polarize and experts depolarize public support for COVID-19 management policies across countries

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PNAS – Proceedings of the National Academy of Sciences of the United States
January 11, 2022; vol. 119 no. 3
https://www.pnas.org/content/119/3

 

Psychological and Cognitive Sciences
Open Access
Politicians polarize and experts depolarize public support for COVID-19 management policies across countries
Alexandra Flores, Jennifer C. Cole, Stephan Dickert, Kimin Eom, Gabriela M. Jiga-Boy, Tehila Kogut, Riley Loria, Marcus Mayorga, Eric J. Pedersen, Beatriz Pereira, Enrico Rubaltelli, David K. Sherman, Paul Slovic, Daniel Västfjäll, and Leaf Van Boven
PNAS January 18, 2022 119 (3) e2117543119; https://doi.org/10.1073/pnas.2117543119

Research Synthesis, HIV Prevention Response, and Public Health: CDC’s HIV/AIDS Prevention Research Synthesis Project

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Public Health Reports
Volume 137 Issue 1, January/February 2022
https://journals.sagepub.com/toc/phrg/137/1

 

Topical Review
Research Synthesis, HIV Prevention Response, and Public Health: CDC’s HIV/AIDS Prevention Research Synthesis Project
Linda J. Koenig, PhD, Cynthia M. Lyles, PhD, Darrel Higa, PhD, Mary M. Mullins, MSLS, Theresa A. Sipe, PhD, MPHfor the HIV/AIDS Prevention Research Synthesis Project
First Published February 26, 2021; pp. 32–47

Epidemiological Characteristics and Transmission Patterns of COVID-19 Cases Among Children and Adolescents Aged 0–18 Years in South Korea

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Risk Management and Healthcare Policy
https://www.dovepress.com/risk-management-and-healthcare-policy-archive56
[Accessed 12 Feb 2022]

 

Original Research
Epidemiological Characteristics and Transmission Patterns of COVID-19 Cases Among Children and Adolescents Aged 0–18 Years in South Korea
Jang J, Hwang MJ, Kim YY, Park SY, Yoo M, Kim SS, Lee S, Kwon D
Published Date: 9 February 2022

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

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Science
Volume 375| Issue 6581| 11 Feb 2022
https://www.science.org/toc/science/current

 

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera
BY Alexander Muik […] Uğur Şahin
18 Jan 2022: 678-680
Open Access
Sera from individuals vaccinated with three doses of the Pfizer/BioNtech mRNA vaccine BNT162b2 can neutralize the SARS-CoV-2 Omicron variant.

Robust immune responses are observed after one dose of BNT162b2 mRNA vaccine dose in SARS-CoV-2–experienced individuals

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Science Translational Medicine
Volume 14| Issue 631| 9 Feb 2022
https://www.science.org/toc/stm/current

 

Research Articles
Robust immune responses are observed after one dose of BNT162b2 mRNA vaccine dose in SARS-CoV-2–experienced individuals
BY Marie I. Samanovic, et al.
09 Feb 2022
Open Access
Prior history of COVID-19 enhances adaptive immune responses to mRNA vaccination.

Environmentally sustainable practices in global health research and higher education institutions: Lessons from consultation with the TropEd Global Health institutions

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Tropical Medicine & International Health
Volume 27, Issue 2 Pages: i-iv, 121-216 February 2022
https://onlinelibrary.wiley.com/toc/13653156/current

 

EDITORS’ CHOICE
Open Access
Environmentally sustainable practices in global health research and higher education institutions: Lessons from consultation with the TropEd Global Health institutions
Kate Whitfield, Alexandru Cretu, Teun Bousema, Justin Cohen
Pages: 122-128
First Published: 21 December 2021

Epidemiology of 4963 deaths associated with COVID-19 during three pandemic waves in a Latin American city with a high mortality rate, 2020–2021

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Tropical Medicine & International Health
Volume 27, Issue 2 Pages: i-iv, 121-216 February 2022
https://onlinelibrary.wiley.com/toc/13653156/current

 

RESEARCH ARTICLES
Epidemiology of 4963 deaths associated with COVID-19 during three pandemic waves in a Latin American city with a high mortality rate, 2020–2021
Erika Viana-Cárdenas, Abel Triana, Humberto Mendoza, Emiro Buendia, Diego Viasus
Pages: 158-164
First Published: 07 December 2021

Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemic in Africa reveals emergence of promising African biomedical research and persisting asymmetry of international collaborations

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Tropical Medicine & International Health
Volume 27, Issue 2 Pages: i-iv, 121-216 February 2022
https://onlinelibrary.wiley.com/toc/13653156/current

Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemic in Africa reveals emergence of promising African biomedical research and persisting asymmetry of international collaborations
Serge Tonen-Wolyec, Dieu-Merci Mbumba Lupaka, Salomon Batina-Agasa, François-Xavier Mbopi Keou, Laurent Bélec

 

Pages: 137-148
First Published: 05 January 2022

Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration? – A review of guidelines in non-endemic countries

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Tropical Medicine & International Health
Volume 27, Issue 2 Pages: i-iv, 121-216 February 2022
https://onlinelibrary.wiley.com/toc/13653156/current

 

REVIEWS
Open Access
Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration? – A review of guidelines in non-endemic countries
Marc T. Visser, Rens Zonneveld, Thomas J. Peto, Michele van Vugt, Arjen M. Dondorp, Rob W. van der Pluijm
Pages: 129-136
First Published: 03 January 2022

Mass vaccination campaign during the 2016 influenza outbreak in Panama: Challenges and implications for COVID-19 vaccination efforts

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Discussion Full text access
Mass vaccination campaign during the 2016 influenza outbreak in Panama: Challenges and implications for COVID-19 vaccination efforts
Franz Castro, Juan Miguel Pascale, Itzel Slocum Hewitt, Arlene Calvo
Pages 555-557

Did the European suspension of the AstraZeneca vaccine decrease vaccine acceptance during the COVID-19 pandemic?

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Short communication Open access
Did the European suspension of the AstraZeneca vaccine decrease vaccine acceptance during the COVID-19 pandemic?
Michael Bang Petersen, Frederik Jørgensen, Marie Fly Lindholt
Pages 558-561

Immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 with 12-dose vials: An interim analysis

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Open access
Immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 with 12-dose vials: An interim analysis
Anan Manomaipiboon, Uraporn Phumisantiphong, Jakravoot Maneerit, Yupin Chalearmchai, … Thananda Trakarnvanich
Pages 587-593

Does a major change to a COVID-19 vaccine program alter vaccine intention? A qualitative investigation

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Open access
Does a major change to a COVID-19 vaccine program alter vaccine intention? A qualitative investigation
Samantha J. Carlson, Lara McKenzie, Leah Roberts, Christopher C. Blyth, Katie Attwell
Pages 594-600

Levels and factors derived from the Health Action Process Approach of behavioral intentions to take up COVID-19 vaccination: A random population-based study

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Full text access
Levels and factors derived from the Health Action Process Approach of behavioral intentions to take up COVID-19 vaccination: A random population-based study
Yanqiu Yu, Wanru Jia, Mason M.C. Lau, Joseph T.F. Lau
Pages 612-620

Childhood vaccination timeliness following maternal migration to an informal urban settlement in Kenya

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Abstract only
Childhood vaccination timeliness following maternal migration to an informal urban settlement in Kenya
Julia M. Porth, Abram L. Wagner, Emily Treleaven, Nancy L. Fleischer, … Matthew L. Boulton
Pages 627-639

A non-inferiority trial comparing two killed, whole cell, oral cholera vaccines (Cholvax vs. Shanchol) in Dhaka, Bangladesh

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Open access
A non-inferiority trial comparing two killed, whole cell, oral cholera vaccines (Cholvax vs. Shanchol) in Dhaka, Bangladesh
Fahima Chowdhury, Afroza Akter, Taufiqur Rahman Bhuiyan, Imam Tauheed, … Firdausi Qadri
Pages 640-649

Vaccine initiation and 3-dose series completion of 4vHPV vaccine among US insured males 2012–2016

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Vaccine
Volume 40, Issue 4 Pages 555-690 (28 January 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/4

 

Research article Abstract only
Vaccine initiation and 3-dose series completion of 4vHPV vaccine among US insured males 2012–2016
Kandace L. Amend, Bruce Turnbull, Li Zhou, Morgan A. Marks, … John D. Seeger
Pages 682-688

Pre-Print Servers

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Pre-Print Servers

 

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 12 Feb 2022]

Research Article metrics AWAITING PEER REVIEW
Modeling anticipated changes in numbers of SARS-CoV-2 infections within communities due to immunization campaigns [version 1; peer review: awaiting peer review]
Kurt Frey, Brittany Hagedorn, Kevin A. McCarthy, Raymond Hutubessy, Susan Annemarie Wang
Peer Reviewers Invited
Funder
Global Good Fund
PUBLISHED 09 Feb 2022

 

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…

Impact of COVID-19 pandemic and anti-pandemic measures on tuberculosis, viral hepatitis, HIV/AIDS and malaria – a systematic review
Barbora Kessel, Torben Heinsohn, Jördis J Ott, Jutta Wolff, Max J Hassenstein, Berit Lange
medRxiv 2022.02.10.22270782; doi: https://doi.org/10.1101/2022.02.10.22270782

Fundamental limits on inferring epidemic resurgence in real time using effective reproduction numbers
Kris V Parag, Christl A. Donnelly
medRxiv 2021.09.08.21263270; doi: https://doi.org/10.1101/2021.09.08.21263270

SARS-CoV-2 neutralization after mRNA vaccination and variant breakthrough infection
Christian Gaebler, Justin DaSilva, Eva Bednarski, Frauke Muecksch, Fabian Schmidt, Yiska Weisblum, Katrina Millard, Martina Turroja, Alice Cho, Zijun Wang, Marina Caskey, Michel C. Nussenzweig, Paul Bieniasz, Theodora Hatziioannou
medRxiv 2022.02.09.22270692; doi: https://doi.org/10.1101/2022.02.09.22270692

Long term antibody response to SARS-CoV-2 in children
Gabor A. Dunay, Madalena Barroso, Mathias Woidy, Marta K. Danecka, Geraldine Engels, Katharina Hermann, Friederike S. Neumann, Kevin Paul, Jan Beime, Gabriele Escherich, Kristin Fehse, Lev Grinstein, Franziska Haniel, Luka J. Haupt, Laura Hecher, Torben Kehl, Christoph Kemen, Markus J. Kemper, Robin Kobbe, Aloisa Kohl, Thomas Klokow, Dominik Noerz, Jakob Olfe, Friderike Schlenker, Jessica Schmiesing, Johanna Schrum, Freya Sibbertsen, Philippe Stock, Stephan Tiede, Eik Vettorazzi, Dimitra E. Zazara, Antonia Zapf, Marc Luetgehetmann, Jun Oh, Thomas S. Mir, Ania C. Muntau, C19.CHILD Study Group, Soeren W. Gersting
medRxiv 2022.02.11.22270611; doi: https://doi.org/10.1101/2022.02.11.22270611

COVID-19 vaccine hesitancy in diverse groups in the UK – is the driver economic or cultural in student populations?
Francis Drobniewski, Dian Kusuma, Agnieszka Broda, Enrique Castro-Sanchez, Raheelah Ahmad
medRxiv 2021.12.14.21267773; doi: https://doi.org/10.1101/2021.12.14.21267773

Ethnic disparities in immunisation: analyses of zero-dose prevalence in 64 low- and middle-income countries
Bianca Oliveira Cata-Preta, Thiago Melo Santos, Andrea Wendt, Daniel R Hogan, Tewodaj Mengistu, Aluisio Jardim Dornellas Barros, Cesar Gomes Victora
medRxiv 2022.02.09.22270671; doi: https://doi.org/10.1101/2022.02.09.22270671
Abstract
Background The Sustainable Development Goals (SDGs) recommend stratification of health indicators by ethnic group, yet there are few studies that have assessed if there are ethnic disparities in childhood immunisation in low and middle income countries (LMICs).
Methods We identified 64 LMICs with standardized national surveys carried out since 2010, which provided information on ethnicity or a proxy variable and on vaccine coverage; 339 ethnic groups across the 64 countries were identified after excluding those with fewer than 50 children in the sample and countries with a single ethnic group. Lack of vaccination with diphtheria-pertussis-tetanus (DPT) vaccine, a proxy for no access to routine vaccination or zero-dose status, was the outcome of interest. Differences among ethnic groups were assessed using a chi-squared test for heterogeneity. Additional analyses controlled for household wealth, maternal education and urban-rural residence.
Findings The median gap between the highest and lowest zero-dose prevalence ethnic groups in all countries was equal to 10 percentage points (interquartile range 4-22; range 1 to 84) and the median ratio was 3.3 (interquartile range 1.8-6.7; range 1.1-30.4). In 35 of the 64 countries, there was significant heterogeneity in zero-dose prevalence among the ethnic groups. In most countries, adjustment for wealth, education and residence made little difference to the ethnic gaps, but in four countries (Angola, Benin, Nigeria, and Philippines) the high-low ethnic gap decreased by over 15 pp after adjustment. Children belonging to a majority group had 29% lower prevalence of zero-dose compared to the rest of the sample.
Interpretation Statistically significant ethnic disparities in child immunisation were present in over half of the countries studied. Such inequalities have been seldom described in the published literature. Regular analyses of ethnic disparities are essential for monitoring trends, targeting resources and assessing the impact of health interventions to ensure zero-dose children are not left behind in the Sustainable Development Goals era.

How many relevant SARS-CoV-2 variants might we expect in the future?
Roberto Littera, Maurizio Melis
medRxiv 2021.11.17.21266463; doi: https://doi.org/10.1101/2021.11.17.21266463

Safety and Efficacy of Preventative COVID Vaccines: The StopCoV Study
Sharon Walmsley, Leah Szadkowski, Bradly Wouters, Rosemarie Clarke, Karen Colwill, Paula Rochon, Michael Brudno, Rizani Ravindran, Janet Raboud, Allison McGeer, Amit Oza, Christopher Graham, Amanda Silva, Dorin Manase, Laura Parente, Jacqueline Simpson, Roaya Monica Dayam, Adrian Pasculescu, Anne-Claude Gingras
medRxiv 2022.02.09.22270734; doi: https://doi.org/10.1101/2022.02.09.22270734

Model-based estimates of deaths averted and cost per life saved by scaling-up mRNA COVID-19 vaccination in low and lower-middle income countries in the COVID-19 Omicron variant era
Alexandra Savinkina, Alyssa Bilinski, Meagan C. Fitzpatrick, A. David Paltiel, Zain Rizvi, Joshua A. Salomon, Tommy Thornhill, Gregg Gonsalves
medRxiv 2022.02.08.22270465; doi: https://doi.org/10.1101/2022.02.08.22270465
[See Featured Journal Articles above for detail]

A recombinant BCG-based vaccine against the human respiratory syncytial virus induces a balanced cellular immune response against viral and mycobacterial antigens
Gaspar A. Pacheco, Nicolás M. S. Gálvez, Catalina A. Andrade, Yaneisi Vázquez, Linmar Rodríguez-Guilarte, Pablo A. González, Susan M. Bueno, Alexis M. Kalergis
medRxiv 2022.02.07.22270648; doi: https://doi.org/10.1101/2022.02.07.22270648

Clinical and Economic Impact of COVID-19 on Plantation Workers: Preliminary Results from the Guatemala Agricultural Workers and Respiratory Illness Impact (AGRI) Study
Daniel Olson, Diva M. Calvimontes, Molly M. Lamb, Gerber Guzman, Edgar Barrios, Andrea Chacon, Neudy Rojop, Kareen Arias, Melissa Gomez, Guillermo Antonio Bolanos, Jose Monzon, Anna N. Chard, Chelsea Iwamoto, Lindsey M. Duca, Nga Vuong, Melissa Fineman, Kelsey Lesteberg, David Beckham, Mario L. Santiago, Kendra Quicke, Gregory Ebel, Emily Zielinski Gutierrez, Eduardo Azziz-Baumgartner, Frederick G. Hayden, Hani Mansour, Kathryn Edwards, Lee S. Newman, Edwin J. Asturias
medRxiv 2022.02.07.22270274; doi: https://doi.org/10.1101/2022.02.07.22270274

A “step too far” or “perfect sense”? A qualitative study of British adults’ views on mandating COVID-19 vaccination and vaccine passports
Martine Stead, Allison Ford, Douglas Eadie, Hannah Biggs, Claire Elliott, Michael Ussher, Helen Bedford, Kathryn Angus, Kate Hunt, Anne Marie MacKintosh, Curtis Jessop, Andy MacGregor
medRxiv 2022.02.07.22270458; doi: https://doi.org/10.1101/2022.02.07.22270458

Time to reinfection and vaccine breakthrough SARS-CoV-2 infections: a retrospective cohort study
Sevda Molani, Andrew M. Baumgartner, Yeon Mi Hwang, Venkata R. Duvvuri, Jason D. Goldman, Jennifer J. Hadlock
medRxiv 2022.02.07.22270613; doi: https://doi.org/10.1101/2022.02.07.22270613

Effectiveness of Covid-19 Vaccines against the SARS-COV-2-Delta (B.1.617.2) in China-A Real World Study
Xinge Ma, Jianfeng Han, Hongxia Li, Chang Liu
medRxiv 2022.02.07.22270490; doi: https://doi.org/10.1101/2022.02.07.22270490

Wellcome Open Research [to 12 Feb 2022]
https://wellcomeopenresearch.org/browse/articles
[Accessed 12 Feb 2022]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Research Article metrics AWAITING PEER REVIEW
Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK [version 1; peer review: awaiting peer review]
Cori Campbell, Tingyan Wang, David A. Smith, Oliver Freeman, Theresa Noble, Kinga A Várnai, Steve Harris, Hizni Salih, Gail Roadknight, Stephanie Little, Ben Glampson, Luca Mercuri, Dimitri Papadimitriou, Christopher R Jones, Vince Taylor, Afzal Chaudhry, Hang Phan, Florina Borca, Josune Olza, Frazer Warricker, Luis Romão, David Ramlakhan, Louise English, Paul Klenerman, Monique I. Andersson, Jane Collier, Eleni Nastouli, Salim I. Khakoo, William Gelson, Graham S. Cooke, Kerrie Woods, Jim Davies, Eleanor Barnes, Philippa C. Matthews
Peer Reviewers Invited
Funders
Wellcome Trust
GlaxoSmithKline
NIHR Oxford Biomedical Research Centre
PUBLISHED 11 Feb 2022

Research Article metrics AWAITING PEER REVIEW
Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study [version 1; peer review: awaiting peer review]
Caroline Barker, Katharine Collet, Diane Gbesemete, Maria Piggin, Daniella Watson, Philippa Pristerà, Wendy Lawerence, Emma Smith, Michael Bahrami-Hessari, Halle Johnson, Katherine Baker, Ambar Qavi, Carmel McGrath, Christopher Chiu, Robert C. Read, Helen Ward
Peer Reviewers Invited
Funders
Wellcome
GCRF Networks in Vaccines Research and Development
National Institute of Health Research
PUBLISHED 10 Feb 2022

Open Letter metrics
Revised
Towards a feminist philosophy of engagements in health-related research [version 2; peer review: 2 approved]
Sonja Erikainen, Ellen Stewart, Angela Marques Filipe, Sarah Chan, Sarah Cunningham-Burley, Sophie Ilson, Gabrielle King, Carol Porteous, Stephanie Sinclair, Jamie Webb
Peer Reviewers Mary Madden; Kieran C. O’Doherty
Funder
Wellcome Trust
LATEST VERSION PUBLISHED 10 Feb 2022

Open Letter metrics AWAITING PEER REVIEW
A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses [version 1; peer review: awaiting peer review]
Nothando Ngwenya, Jennifer Ilo Van Nuil, Deborah Nyirenda, Mary Chambers, Phaik Yeong Cheah, Janet Seeley, Primus Chi, Lindiwe Mafuleka, Busisiwe Nkosi, Dorcas Kamuya, Alun Davies, Mira Leonie Schneiders, Noni Mumba, Siphephelo Dlamini, Nicola Desmond, Vicki Marsh, Dinnah Rippon, Michael Parker, Sassy Molyneux
Peer Reviewers Invited
Funder
Wellcome Trust
PUBLISHED 10 Feb 2022
Abstract
Covid-19 continues to teach the global community important lessons about preparedness for research and effective action to respond to emerging health threats.  We share the COVID-19 experiences of a pre-existing cross-site ethics network-the Global Health Bioethics Network-which brings together researchers and practitioners from Africa, Europe, and South east Asia. We describe the network and its members and activities, and the work-related opportunities and challenges we faced over a one-year period during the pandemic. We highlight the value of having strong and long-term empirical ethics networks embedded across diverse research institutions to be able to: 1) identify and share relevant ethics challenges and research questions and ways of ’doing research’; 2) work with key stakeholders to identify appropriate ways to contribute to the emerging health issue response – e.g. through ethics oversight, community engagement, and advisory roles at different levels; and 3) learn from each other and from diverse contexts to advocate for positive change at multiple levels. It is our view that being both embedded and long term offers particular opportunities in terms of deep institutional and contextual knowledge and relationships with and access to a wide range of stakeholders in place. Being networked offers opportunities to draw upon a wide range of expertise and perspectives operating at multiple levels, and to bring together internal and external perspectives (i.e. different positionalities). Long term funding means that the people and resources are in place and ready to respond in a timely way. However, many tensions and challenges remain, including difficulties in negotiating power and politics regarding roles that researchers and research institutions play in an emergency, and the position of empirical ethics activities in programmes of research more specifically. We discuss some of these tensions and challenges, and consider the implications for our own and similar networks in future.

Think Tanks

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Think Tanks
 
 
Brookings
http://www.brookings.edu/
Accessed 12 Feb 2022
Future Development
Why global vaccine equity is the prescription for a full recovery
Indermit Gill and Michele Ruta
Friday, February 11, 2022

Testimony
Improving access to quality public education in Africa
Rebecca Winthrop
Friday, February 11, 2022
 
 
Center for Global Development [to 12 Feb 2022]
https://www.cgdev.org/
Accessed 12 Feb 2022
COVID-19 Vaccine Development and Rollout in Historical Perspective
Publication
February 9, 2022
This paper explores the historical record in the development and deployment of vaccines globally and puts the COVID-19 vaccine rollout in that context. Although far more can be done and should be done to speed equitable access to vaccines in the COVID-19 response, it is worth noting the revolutionary speed of both the vaccine development and the diffusion process, and the potential good news that this signals for the future of pandemic preparedness and response.

New Study: COVID-19 Vaccine Rollout Fastest in Global History
February 9, 2022
WASHINGTON—The COVID-19 vaccine rollout so far has been the fastest in global history and unprecedented in scale, according to a new study released today from the Center for Global Development, which also emphasized the considerable global inequality in access to vaccines to date.
Researchers at the global think tank assessed how vaccines have been developed and deployed against 15 older infectious diseases and compared those efforts to the response to COVID-19.

The COVID-19 Vaccine Rollout Was the Fastest in Global History, but Low-Income Countries Were Left Behind
February 9, 2022
The reaction to COVID-19 has been record-breaking. Today we release a paper that reports on the development and rollout of COVID-19 vaccines in historical perspective, and it suggests a pattern of unparalleled, but still deeply inequitable, progress.
Amanda Glassman, Charles Kenny and George Yang

The Vaccine Mark-Up: Counting More in ODA than We Paid for Vaccines is Illogical, Immoral, and Unpopular
February 7, 2022
Someone in a high-income country is 11x more likely to have been fully inoculated than someone in a low-income country. We set out here how the OECD plans to count COVID vaccines, why this reduces the UK’s overall spending on ODA, and how MPs think we should count them.
Euan Ritchie, Anthony McDonnell and Ranil Dissanayake
 
 
Chatham House [to 12 Feb 2022]
https://www.chathamhouse.org/
Accessed 12 Feb 2022
[No new digest content identified]

 
 
CSIS
https://www.csis.org/
Accessed 12 Feb 2022
Commentary
China May Move beyond Zero-Covid. That Could Benefit Us All.
February 9, 2022 | By J. Stephen Morrison, Scott Kennedy

 
 

Kaiser Family Foundation
https://www.kff.org/search/?post_type=press-release
Accessed 12 Feb 2022
February 10, 2022 News Release
Telehealth Accounted for 8% of Outpatient Visits More Than a Year into COVID-19 Pandemic, Suggesting a More Permanent Shift in How Patients Receive Care
Telehealth use skyrocketed during the early months of the pandemic. While it has since decreased somewhat from that high, it still represents a much more substantial share of health care than before COVID, a new KFF-Epic Research analysis finds. From March through August 2021, 8% of all outpatient visits were…