Vaccines: The Week in Review 15 June 2013

 

Editor’s Notes:

 

- Vaccines: The Week in Review is a weekly digest — summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated “8 June 2013″

 

- Email Summary: Vaccines: The Week in Review is published as a single email summary, scheduled for release each Saturday eveningbefore midnight (EDT in the U.S.). If you would like to receive the email version, please send your request to david.r.curry@centerforvaccineethicsandpolicy.org.

 

- pdf version: A pdf of the current issues is available here: Vaccines_The Week in Review_15 June 2013

 

- Twitter: Readers can also follow developments on twitter: @vaxethicspolicy.

 

- Links: We endeavor to test each link as we incorporate it into any post, but recognize that some links may become “stale” as publications and websites reorganize content over time. We apologize in advance for any links that may not be operative. We believe the contextual information in a given post should allow retrieval, but please contact us as above for assistance if necessary.

 

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GAVI Alliance Board to develop a long-term strategy to support IPV introduction

The GAVI Alliance Board said it has requested an “in-depth analysis to inform its decisions on the future of GAVI’s vaccines portfolio and requested the GAVI Secretariat to develop a long-term strategy on how GAVI will support the introduction of Inactivated Polio Vaccine in partner countries.”  The request “…was taken based on initial assessments of the potential effect of vaccine interventions on a range of life-threatening diseases. The cost and user-friendliness of vaccines, as well as their potential to benefit vulnerable groups and to aid outbreak prevention were also considered.” The requested analysis WILL “evaluate the potential impact vaccines could have in five disease areas under consideration for future Alliance support: cholera, influenza (for pregnant women), malaria, rabies and further support for yellow fever.” Final decisions on future vaccine support are expected to be taken at the November 2013 GAVI Board meeting. GAVI’s support for vaccines already in its portfolio remains unchanged.

Separately, the Board agreed that the GAVI Alliance “should play a lead role in the introduction of Inactivated Polio Vaccine (IPV) into routine immunisation services in countries where GAVI currently works” and “recognised the importance of strong partnership and complementarity between the GAVI Alliance and the Global Polio Eradication Initiative and requested the GAVI Secretariat to present a long-term strategy in support of the Alliance’s specific role and activities in relation to IPV to the Board by November 2013. “


http://www.gavialliance.org/library/news/statements/2013/gavi-board-asks-to-begin-preparations-for-introduction-of-inactivated-polio-vaccine-and-considers-investment-in-other-new-vaccines/

GPEI: Emergency meeting called in response to the polio outbreak in the Horn of Africa, 9–10 June 2013

GPEI: Emergency meeting called in response to the polio outbreak in the Horn of Africa, 9–10 June 2013

WHO Regional Office for the Eastern Mediterranean hosted a two-day emergency meeting in Cairo, Egypt, from 9 to 10 June 2013, on the response to the polio outbreak in the Horn of Africa. The meeting was to be attended by the Chairman of the Horn of Africa Technical Advisory Group, and representatives of WHO headquarters, WHO Regional Office for Africa, and WHO country offices in Kenya, Ethiopia, Somalia and Yemen. It will be chaired by Dr Ala Alwan, WHO Regional Director for the Eastern Mediterranean.

The objectives of the meeting were to:

:: review the current status and risks for poliovirus circulation in Somalia, Kenya, Ethiopia and Yemen

:: review and strengthen national response plans to rapidly stop the polio outbreak and prevent its spread to Ethiopia, Yemen and other countries

:: review and strengthen intercountry and inter-regional coordination of the outbreak response in the Horn of Africa

:: activate and implement the necessary emergency protocols and process to urgently deploy human, logistic and financial resources for a robust outbreak response and develop advocacy plans to optimize access to children in Somalia

:: enhance political commitment and support for the national outbreak response.

Optimal mechanisms and protocols for intercountry and inter-regional coordination will be discussed in the meeting, together with the advocacy and outreach needed to optimize access to children in Somalia and enhance political commitment and support for the national outbreak response.


http://www.emro.who.int/polio/polio-events/response-polio-outbreak-horn-of-africa.html

GPEI Update: Polio this week – As of 12 June 2013

Update: Polio this week – As of 12 June 2013
Global Polio Eradication Initiative

http://www.polioeradication.org/Dataandmonitoring/Poliothisweek.aspx

[Editor’s extract and bolded text]

:: An emergency Horn of Africa polio outbreak meeting was held this week (9-10 June) in Cairo, Egypt, hosted by the WHO Regional Office for the Eastern Mediterranean (EMRO). Chaired by EMRO Regional Director Dr Ala Alwan, the meeting was attended by the Chair of the Horn of Africa Technical Advisory Group, as well as representatives from WHO headquarters (including Dr Bruce Aylward, Assistant Director-General for Polio, Emergencies and Country Collaboration), EMRO, and country office teams from Somalia, Kenya, Ethiopia and Yemen.

:: The meeting reviewed the current status and risks associated with the outbreak, as well as outbreak response activities and their expected impact and discussed strategies to further increasing support to countries and strengthening the outbreak response. [see meeting coverage above]

Nigeria
::One new WPV case was reported in the past week (WPV1 from Kano), bringing the total number of WPV cases for 2013 to 25. It is the most recent WPV case in the country and had onset of paralysis on 4 May.

Pakistan
:: Four new WPV cases were reported in the past week (WPV1s from Federally Administered Tribal Areas – FATA, including three from Khyber Agency), bringing the total number of WPV cases for 2013 to 14. One of the newly-reported cases is the most recent WPV case in the country and had onset of paralysis on 19 May.

:: One new cVDPV2 case was reported in the past week (from Gadap town, greater Karachi, Sindh), bringing the total number of cVDPV2 cases for 2013 to five. It is the most recent cVDPV2 case in the country and had onset of paralysis on 8 May

Horn of Africa
:: Five new WPV cases were reported in the past week (two WPV1s from Somalia and three WPV1s from Kenya), bringing the total number of WPV1 cases in the region to 14 (nine WPV1s from Somalia and five WPV1s from Kenya). Two of these new cases are the most recent and had onset of paralysis on 18 May (both from Kenya).

:: Outbreak response activities are continuing across the Horn of Africa.

:: In Somalia, two large-scale immunization campaigns have already been implemented, including in Banadir (which includes Mogadishu), including targeting children aged less than ten years. Lessons from these campaigns are now being addressed in preparation of the next rounds starting on 12 June. In Banadir, all age groups are being targeted. Focus is on fine-tuning microplans to include schools, more clearly define vaccinator team daily workloads, improving supervision and expanding the scope and content of monitoring activities.

:: In Kenya, immunization activities began on 26 May to reach nearly 440,000 children aged less than 15 years across the Dadaab area. Preparations are ongoing for the next SNIDs, on 15 June, covering broader areas including all age groups in the Dadaab area. Further campaigns planned for late June and mid-August.

:: Immunization campaigns are also planned and being conducted in other areas of the Horn of Africa, notably Ethiopia and Yemen, to urgently boost population immunity levels and minimize the risk of spread of the outbreak.

:: In Ethiopia, in border areas with Kenya and Somalia, an immunization activity was held on 31 May (targeting children aged less than 15 years). Focus was particularly on reaching children in refugee camps. Broader activities are planned to start 16 June and in early July.

:: In Yemen, activities were held last week (2-5 June) to reach 2.1 million children, with a second round planned for late June to reach 3.5 million children and National Immunization Days in August.

WHO: Global Alert and Response (GAR) – Disease Outbreak News MERS-CoV; Yellow Fever

WHO: Global Alert and Response (GAR) – Disease Outbreak News

http://www.who.int/csr/don/2013_03_12/en/index.html

Middle East respiratory syndrome coronavirus (MERS-CoV) – update 14 June 2013
Excerpt
14 June 2013 – The Ministry of Health in Saudi Arabia has announced an additional three laboratory-confirmed cases, including one death with Middle East respiratory syndrome coronavirus (MERS-CoV)…
…Globally, from September 2012 to date, WHO has been informed of a total of 58 laboratory-confirmed cases of infection with MERS-CoV, including 33 deaths.

WHO has received reports of laboratory-confirmed cases originating in the following countries in the Middle East to date: Jordan, Qatar, Saudi Arabia, and the United Arab Emirates (UAE). France, Germany, Italy, Tunisia and the United Kingdom also reported laboratory-confirmed cases; they were either transferred there for care of the disease or returned from the Middle East and subsequently became ill. In France, Italy, Tunisia and the United Kingdom, there has been limited local transmission among patients who had not been to the Middle East but had been in close contact with the laboratory-confirmed or probable cases…

Yellow fever in the Democratic Republic of Congo 14 June 2013
Excerpt
14 June 2013 – The Ministry of Health of the Democratic Republic of Congo (DRC) is launching an emergency mass vaccination campaign against yellow fever from 20 June 2013, following laboratory confirmation of six cases in the country on 6 June 2013…

…The mass vaccination campaign aims to cover at least 503,426 people in the three affected health zones.

The International Coordinating Group on Yellow Fever Vaccine Provision (YF-ICG11) will provide 559,000 doses of yellow fever vaccine for the mass vaccination campaign run by the Ministry of Health in DRC, with support from the GAVI Alliance, Medicins Sans Frontiers and other partners. WHO is closely supporting the management of the outbreak in monitoring, preventive and control activities in the field, and resource mobilization…

Organization of American States’ Resolution “Elimination of Neglected Diseases and Other Poverty-Related Infections”

Statement: On the Occasion of the Organization of American States’ Resolution “Elimination of Neglected Diseases and Other Poverty-Related Infections”
Sabin Vaccine Institute
June 13, 2013

Excerpt
Last week, the Organization of American States (OAS), the main political and social governmental forum for nations in Latin America and the Caribbean, approved a resolution supporting the control and elimination of neglected tropical diseases (NTDs) during the 43rd General Assembly in Antigua, Guatemala.

Ambassador Hubert J. Charles, Permanent Representative of Dominica to OAS, presented a resolution to endorse the Pan American Health Organization’s 2009 resolution, “Elimination of Neglected Diseases and Other Poverty-Related Infections.” While not every Member State has NTDs, there was broad agreement that the OAS resolution would add value to existing efforts and renew a collective commitment to significantly reduce the prevalence of these diseases in the region by 2015. Fifteen countries co-sponsored the resolution and it received approval from the majority of the 35 independent states represented in the OAS.

Dr. Peter Hotez, president of the Sabin Vaccine Institute, issued the following statement applauding the OAS for their leadership in the fight against NTDs:

We applaud the Organization of American States for its recognition of the important goal of reducing the burden of infectious and neglected tropical diseases in Latin America and the Caribbean.

   These diseases continue to perpetuate the cycle of poverty, often holding back marginalized communities. Though the region has made significant progress towards NTD control and elimination, more work still needs to be done to alleviate the suffering of the 100 million people currently infected in this region.  This resolution aligns with the OAS’ core mission to reduce poverty among its Member States. Success in eliminating these diseases will bolster the region’s ongoing efforts to improve health systems, equity and economic development.

   We expect this new political endorsement to stimulate interest, action and the necessary resources to meet the targets outlined by the Pan American Health Organization as we approach the 2015 deadline for a number of NTD elimination goals.


http://www.sabin.org/updates/pressreleases/statement-sabin-vaccine-institute-occasion-organization-american-states%E2%80%99