Emergence and pandemic potential of swine-origin H1N1 influenza virus

Nature
Volume 459 Number 7249 pp889-1026
http://www.nature.com/nature/journal/v459/n7249/

Review
Emergence and pandemic potential of swine-origin H1N1 influenza virus

Gabriele Neumann1, Takeshi Noda2 & Yoshihiro Kawaoka1,2,3,4

Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of new strains will continue to pose challenges to public health and the scientific communities. A prime example is the recent emergence of swine-origin H1N1 viruses that have transmitted to and spread among humans, resulting in outbreaks internationally. Efforts to control these outbreaks and real-time monitoring of the evolution of this virus should provide us with invaluable information to direct infectious disease control programmes and to improve understanding of the factors that determine viral pathogenicity and/or transmissibility.

Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53711, USA
International Research Center for Infectious Diseases,
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan
ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama 332-0012, Japan

Correspondence to: Yoshihiro Kawaoka1,2,3,4 Correspondence should be addressed to Y.K. (Email: kawaokay@svm.vetmed.wisc.edu).

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.