Pneumococcal Conjugate and Polysaccharide Vaccination in Adults

Clinical Infectious Diseases
Volume 52 Issue 6 March 15, 2011
http://www.journals.uchicago.edu/toc/cid/current
Rajeka Lazarus, Elizabeth Clutterbuck, Ly-Mee Yu, Jaclyn Bowman, Elizabeth A. Bateman, Linda Diggle, Brian Angus, Tim E. Peto, Peter C. Beverley, David Mant,
and Andrew J. Pollard

A Randomized Study Comparing Combined Pneumococcal Conjugate and Polysaccharide Vaccination Schedules in Adults
Clin Infect Dis. (2011) 52(6): 736-742 doi:10.1093/cid/cir003

Combined schedules of pneumococcal conjugate and polysaccharide vaccines do not provide enhanced immunogenicity for the seven serotypes tested in comparison to a single dose of pneumococcal conjugate vaccine in adults.