Sabin wins two-year, US$12 million grant from Gates Foundation for human hookworm vaccine

Sabin Vaccine Institute announced receipt of a two-year, US$12 million grant from the Bill & Melinda Gates Foundation “to continue development of a vaccine to prevent human hookworm infection, a parasitic disease that affects 600 million people worldwide.” Hookworm infection, most commonly found in sub-Saharan Africa, Southeast Asia and Latin America, is a significant contributor to the global burden of iron-deficiency anemia that disproportionately affects children and women of reproductive age. The infection results in approximately 65,000 deaths and the loss of up to 22 million disability adjusted life years (DALYs) annually. Hookworm is one of the seven most common neglected tropical diseases (NTDs), which together carry a greater health burden than malaria and tuberculosis and rival that of HIV/AIDS.