Direct and Indirect Effects of Rotavirus Vaccination

Clinical Infectious Diseases
Volume 53 Issue 3 August 1, 2011

Daniel C. Payne, Mary Allen Staat, Kathryn M. Edwards, Peter G. Szilagyi, Geoffrey A. Weinberg, Caroline B. Hall, James Chappell, Aaron T. Curns, Mary Wikswo, Jacqueline E. Tate, Benjamin A. Lopman, Umesh D. Parashar, and the New Vaccine Surveillance Network (NVSN)
Direct and Indirect Effects of Rotavirus Vaccination Upon Childhood Hospitalizations in 3 US Counties, 2006–2009
Clin Infect Dis. (2011) 53(3): 245-253 doi:10.1093/cid/cir307

Active, population-based surveillance from 2006-2009 observed dramatic decreases in rotavirus hospitalization rates among children in 3 US counties. In 2008, reductions were prominent among both vaccine eligible age groups and older, largely unvaccinated children; the latter likely resulting from indirect protection.